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sdhA

Gene
sdha
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Xenopus tropicalis
Length
665 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
72.706 kDa
Sequence
MAFLNVASSRLLSKTLQLGGRVQNCTATCTAATRNFHFSVYGRKDTSAKLSDSISTQYPVVDHDFDAVVVGAGGAGLRAAFGLSEAGFNTACITKLFPTRSHTVAAQGGINAALGNMEDDDWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVIELENYGMPFSRTEQGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCMEDGSIHRFRAKNTVIATGGYGRTFFSCTSAHTCTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSEGERFMERYAPVAKDLASRDVVSRSMTIEIREGRGCGKDKDHVYLQLHHLPPSQLASRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVITHVNGEDRVVPGLYACGEAASASVHGANRLGANSLLDLVVFGRACALSIAESCKPGEPVPSIKENAGEESVANLDKLRFTNGSTRTSELRINMQKTMQNHAAVFRTGSVLKEGCEKLSAINSTMDDIKTFDRGIVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIQGQQKKSFSEHWRKHTLSYVDGKGKVSLEYRPVIDTTLNEDCVSVPPAIRSY
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: sdha

Gene
SDHA
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Bos taurus
Length
665 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (Probable). Can act as a tumor suppressor (By similarity).
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
72.944 kDa
Sequence
MSGVAAVSRLWRARRLALTCTKWSAAWQTGTRSFHFTVDGNKRSSAKVSDAISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMESGECRGVIALCIEDGSIHRIRARNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPAQLAMRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQGVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPSIKPNAGEESVMNLDKLRFANGSIRTSELRLNMQKSMQSHAAVFRVGSVLQEGCEKISSLYGDLRHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGGPRREDFKERVDEYDYSKPIQGQQKKPFEQHWRKHTLSYVDIKTGKVTLEYRPVIDRTLNETDCATVPPAIGSY
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: SDHA

Gene
SDHA
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Gallus gallus
Length
665 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
72.931 kDa
Sequence
MAAVVAASRSLAKCWLRPAVRAWPAACQTHARNFHFTVDGKKNASTKVSDSISTQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEDDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVIELENYGMPFSRTEEGKIYQRAFGGQSLQFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGTIHRFRAKNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTIEIREGRGCGPEKDHVYLQLHHLPPQQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVITHVNGEDKVVPGLYACGEAASASVHGANRLGANSLLDLVVFGRACALTIAETCKPGEPVPSIKPNAGEESVANLDKLRFADGTIRTSEARLNMQKTMQSHAAVFRTGSILQEGCEKLSQIYCDLAHLKTFDRGIVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKFRIDDFDYSKPLQGQQKRPFEEHWRKHTLSYVDVKSGKVTLKYRPVIDRTLNEEDCSSVPPAIRSY
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: SDHA

Gene
SDHA
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Homo sapiens
Length
664 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:24781757). Can act as a tumor suppressor (PubMed:20484225).
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
72.692 kDa
Sequence
MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVGTGKVTLEYRPVIDKTLNEADCATVPPAIRSY
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: SDHA

Gene
SDHA
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Macaca fascicularis
Length
664 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor.
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
72.965 kDa
Sequence
MSGVRRLSRLLSTRRLALAKAWPAVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENRECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLWDLVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKARIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVSTGKVTLEYRPVIDKTLNEADCATVPPAIRSY
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: SDHA

Gene
Sdha
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Mus musculus
Length
664 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor.
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
72.585 kDa
Sequence
MAGVGAVSRLLRGRRLALTGAWPGTLQKQTCGFHFSVGENKKASAKVSDAISTQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACLTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLKHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPSIKANAGEESVMNLDKLRFADGSIRTSELRLNMQKSMQNHAAVFRVGSVLQEGCEKISQLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRVDEYDYSKPIQGQQKKPFGEHWRKHTLSYVDIKTGKVTLEYRPVIDKTLNEADCATVPPAIRSY
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: Sdha

Gene
SDHA
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Sus scrofa
Length
664 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (Probable). Can act as a tumor suppressor (By similarity).
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
72.832 kDa
Sequence
MSGVRAVSRLLRARRLALTWAQPAASPIGARSFHFTVDGNKRSSAKVSDAISTQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRARNTVVATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLAVRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQVVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPSIKPNAGEESVMNLDKLRFANGTIRTSELRLSMQKSMQSHAAVFRVGSVLQEGCEKILRLYGDLQHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDFKERVDEYDYSKPIQGQQKKPFQEHWRKHTLSYVDVKTGKVSLEYRPVIDKTLNEADCATVPPAIRSY
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: SDHA

Gene
SDHA
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Pongo abelii
Length
664 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor.
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
72.692 kDa
Sequence
MSGVRGLSRLLSARRLALAKAWPTVLQTGARGFHFTVDGNKRASAKVSDSISAQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDKVPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKISKLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVSTGKVTLEYRPVIDKTLNEADCATVPPAIRSY
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: SDHA

Gene
sdha
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Danio rerio
Length
661 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
72.078 kDa
Sequence
MAAVCAASRVLGTKILSCKSLPAVCQANRQLHFSIYGKRGDAKISDGVSNQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEQDDWRWHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENFGMPFSRTDDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMEDGECKGVIALCMEDGSIHRFRAKNTVIATGGYGRTFFSCTSAHTSTGDGNAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSEGERFMERYAPNAKDLASRDVVSRSMTIEIREGRGVGPDKDHVHLQLHHLPPQQLAARLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVITYKDGQDHVVPGLYACGEAGCASVHGANRLGANSLLDLVVFGRACALTIAEIDTPGEKLSPLKPNAGEASVANLDKMRYANGSTRTSEIRLNMQKTMQSHAAVFRTGDVLKEGCVKMESVYKSMDDIKTFDRGIVWNTDLVETLELQNLMLNAVQTIVSAEARKESRGAHAREDFKDRVDEYDYSKPLQGQVKKPFEQHWRKHTLSYVDPETGKVTLEYRPVIDSSLDAEDCAAIPPAIRSY
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: sdha

Gene
SdhA
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Drosophila melanogaster
Length
661 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Maintaining electron transport chain function is required to prevent neurodegenerative changes seen in both early- and late-onset disorders.
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
72.343 kDa
Sequence
MSGIMRVPSILAKNAVASMQRAAAVGVQRSYHITHGRQQASAANPDKISKQYPVVDHAYDAIVVGAGGAGLRAAFGLVAEGFRTAVITKLFPTRSHTIAAQGGINAALGNMEEDDWKWHMYDTVKGSDWLGDQDAIHYMTREAPKAVIELENYGMPFSRTQDGKIYQRAFGGQSLKFGKGGQAHRCCAVADRTGHSLLHTLYGQSLSYDCNYFVEYFALDLIFEDGECRGVLALNLEDGTLHRFRAKNTVIATGGYGRAFFSCTSAHTCTGDGTAMVARQGLPSQDLEFVQFHPTGIYGAGCLITEGCRGEGGYLINGNGERFMERYAPVAKDLASRDVVSRSMTIEIMEGRGAGPEKDHVYLQLHHLPPKQLAERLPGISETAMIFAGVDVTREPIPVLPTVHYNMGGVPTNYRGQVITIDKDGKDVIVPGLYAAGEAASSSVHGANRLGANSLLDLVVFGRACAKTIAELNKPGAPAPTLKENAGEASVANLDKLRHANGQITTADLRLKMQKTMQHHAAVFRDGPILQDGVNKMKEIYKQFKDIKVVDRSLIWNSDLVETLELQNLLANAQMTIVSAEARKESRGAHAREDFKVREDEYDFSKPLDGQQKKPMDQHWRKHTLSWVCNDNGDITLDYRNVIDTTLDNEVSTVPPAIRSY
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: SdhA

Gene
Sdha
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Rattus norvegicus
Length
656 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor.
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
71.615 kDa
Sequence
MAGVGAVSRLLRGRRLALAGATRGFHFSVGESKKASAKVSDAISTQYPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACLTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIRAKNTIIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLKHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPPIKANAGEESVMNLDKLRFADGSVRTSELRLSMQKSMQSHAAVFRVGSVLQEGCEKVSQLYGDLQHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSKPIEGQQKKPFAEHWRKHTLSYVDTKTGKVTLDYRPVIDKTLNEADCATVPPAIRSY
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: Sdha

Gene
sdhA
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Dictyostelium discoideum
Length
626 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
68.516 kDa
Sequence
MLSSALKLTKKVCSTKSNGLIRSFSTQTQSRDYAVVDHTYDAIVVGAGGAGLRAALGLTEKGYKTACITKLFPTRSHTVAAQGGINAALGNADQDDWRWHAYDTVKGSDFLGDQDAIHYMCKEAVPTVLELEQYGVPFSRMDDGRIYQRAFGGQSKNFGKGGQATRCCAAADRTGHALLHTLYGQAVKHNTKFFIEYFVTDLIMENGDCRGVVAINLEDGTIHRFRSHATVIATGGYGRAYFSATSAHTCTGDGNAMVIRAGLPCQDLEFVQFHPTGIYGSGCLITEGARGEGGYLLNSSGERFMPRYAPSVADLASRDVVSRSETMEIREGRGVGPEKDHCLLNLTHLSPEIIDERLPGIRETAMIFAGVDVTKEPIPVIPTVHYNMGGIPTNYKGQVITQVDGKDKLVKGLYAAGESACVSVHGANRLGANSLLDIVVFGRAVANEIENTLAKDTPHKPLPPNAGEESIANIDAIRFSNGTRSTAEIRLEMQKIMQRNAAVFRDGQVLKEGVELIDKCARSLINDLKTTDRTMIWNTDLIESLELQNLMTQAVLTMHSAEARKESRGAHAREDYKERDDANWMKHTLSYLDVNTGKVTLNYRPVVSETLDQSEMETIKPFKRVY
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: sdhA

Gene
sdhA
Protein
8-methylmenaquinol:fumarate reductase flavoprotein subunit
Organism
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)
Length
613 amino acids
Function
Flavoprotein subunit of 8-methylmenaquinol:fumarate reductase (MFR), that catalyzes the reduction of fumarate using 8-methylmenaquinol-6 as electron donor. The complex shows no succinate oxidation activity. Is involved in anaerobic metabolism. SdhA contains the dicarboxylate reduction site.
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
66.517 kDa
Sequence
MSEQFTRREFLQSACITMGALAVSTSGVDRAFASSSLPINTSGIPSCDVLIIGSGAAGLRAAVAARKKDPSLNVIVVSKVMPTRSATTMAEGGINGVIDFSEGDSFALHAYDTVKGGDFLVDQDTAMKFAEHAGEAIHELDYIGMPFSRDKNGKVDKRYAGGASKIRCNFSADKTGHILTHTCLDDALKNGVKFLMDHQLLDIGVDNGRCEGVVLRDIRTGTIAPVRAKSVVLATGGYTRVFWNRTSTPYIATGDGAASAMRAGVAFKDPEMLQFHPTGVCHGGVLITEAARGEGGILLNNQGERFMKNYAKKMELAPRDIVSRSIETEIREGRAFGKGMEAYVLLDVTHLGKEKIMRNLPQIRHIGLLFENMDLVEKPIAIRPTAHYSMGGIDVMGLESMSTAIPGLFAAGEAACVSIHGANRLGGNSLCDTVVTGKIAGTNAASFASSAGFGSGTHLHDLTLKWMSRFKEVANGKGEVNEMYAIREELGAVNWDNMGVFRTESRLVALEDKHNELQARYDALRIPNTNPVFNTAFTEYVELGNILLASRAARMGAEARKESRGSHYREDYIKRDDANFLKHSMVTMDSNGKLHLGWKDVVVTQFKIEERKY
Protein
8-methylmenaquinol:fumarate reductase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Paracoccus denitrificans
Length
600 amino acids
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
65.616 kDa
Sequence
MAAYKYETHEYDVVVVGAGGAGLRATLGMAEQGLRTACVTKVFPTRSHTVAAQGGIAASLSNMGPDNWQWHMYDTVKGSDWLGDTDAMEYLAREAPKAVYELEHYGVPFSRTEEGKIYQRPFGGHTTEFGEGPPVQRTCAAADRTGHAILHTLYGQSLKEKAEFFIEYFALDLIITDGACTGVVCWKLDDGTIHVFNAKMVVLATGGYGRAYFSATSAHTCTGDGGGMVARAGLPLQDMEFVQFHPTGIYGSGCLITEGARGEGGYLTNSEGERFMERYAPTYKDLASRDVVSRCITIEIREGRGVGPHKDHMHLNLMHLPPESLAERLPGISESAKIFAGVDVTREPIPILPTVHYNMGGIPTNYWGEVLNPTQDNPDQVFPGLMAVGEAGCASVHGANRLGSNSLIDLVVFGRAAAIRAGQVIDREAQIPTTNKEQVDKALDRFDRIRNADGSVSTADLRLEMQRTMQADAAVFRTDKTLAEGVDKMRVIAGKLSDLKVTDRSLIWNSDLMETLELTNLMPNALATIVAAEARKESRGAHAHEDYPERDDANWRKHSLAWIEGNDVKLAYRPVHLEPLTRQDEGGIDLKKIAPKARVY
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Rickettsia prowazekii (strain Madrid E)
Length
596 amino acids
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
65.445 kDa
Sequence
MTKAYNIIHHKFDVVVVGAGGAGLRSAFGMAKEGLNTACITKIFPTRSHTVAAQGGISAALGNMGEDDWRWHMYDTVKGSDWLGDQDAIEYMCKNAPDAILELEHYGVPFSRTVDGKIYQRPFGGMTTEYGKGKAAQRTCAAADRTGHAILHTLYQQSLKHKVQFFIEYFAIDLLMEDGECRGVVAWNLDDGSLHCFRAHNVVLATGGYGRAYFSATSAHTCTGDGGGMVIRAGLPLQDMEFVQFHPTGIYSAGCLITEGARGEGGYLVNANGERFMERYAPAAKDLASRDVVSRAMTIEIREGRGVGEHKDHVFLHLNHLSPEILHRRLPGISETAKIFAGVDVTKDPIPVLPTVHYNMGGIPTNYQGQVIIKDGKNHNSIVNGIMAIGEAACVSVHGANRLGSNSLLDLVVFGRSSALKAAELIKPASPHKPLQKETLEKIINRFDKVRYANGNILVADLRLKMQRTMQSHVSVFRTQKLLDEGVGMISEIRNRYKDIKINDKSLIWNSDLVEALELDNLLDQALVTVCSAAARKESRGAHAREDYPDRNDRDWIKHTLSSIDDSGKVVLDYKPVTLTTLTDAISAIPPVKRVY
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Length
596 amino acids
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
65.743 kDa
Sequence
MTKAYNIIHHKFDVVVVGAGGAGLRSAFGMAKEGLNTACITKIFPTRSHTVAAQGGISAALGNMGEDDWRWHMYDTVKGSDWLGDQDAIEYMCKNAPDAILELEHYGVPFSRTEDGKIYQRPFGGMTTEYGKGKAAQRTCAAADRTGHAILHTLYQQSLKHKVQFFIEYFAIDLLMEDGECRGVVAWNLDDGSLHCFRAHNVVLATGGYGRAYFSATSAHTCTGDGGGMVIRAGLPLQDMEFVQFHPTGIYSAGCLITEGARGEGGYLVNANGERFMERYAPAAKDLASRDVVSRAMTIEIREGRGVGEYKDHVFLHLNHLSPEILHRRLPGISETAKIFAGVDVTKDPIPVLPTVHYNMGGIPTNYHGQVIIKDGKNHNSIVNGIMAIGEAACVSVHGANRLGSNSLLDLVVFGRSSALKAAELIKPVSPHKPLKKEILEKIINRFDKIRHANGNVLVADLRLQMQRTMQSHVSVFRTQELLDEGARMISEIRNRYKDIKINDKSLIWNSDLVEALELDNLLDQALVTVYSAAARKESRGAHAREDYPDRNDIDWIKHTLSSIDDSGQIILDYKPVTLTTLTDEISTIPPVKRIY
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Rickettsia bellii (strain RML369-C)
Length
596 amino acids
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
65.106 kDa
Sequence
MTKSYNIIHHKFDVIVVGAGGAGLRAAFGMAEEGLNTACISKLFPTRSHTVAAQGGISAALGNMGADDWRWHMYDTVKGSDWLGDQDAIEYMCKNAPDAILELEHYGVPFSRTEEGKIYQRPFGGMTTEYGKGKAAQRTCAAADRTGHAILHTLYQQSLKHKVQFFIEYFAIDLLMENGECRGVVAWNLDDGSLHCFRAHNVVLATGGYGRAYFSATSAHTCTGDGGGMAIRAGLPLQDMEFVQFHPTGIYSAGCLITEGARGEGGYLVNANGERFMERYAPAAKDLASRDVVSRAMTIEIREGRGVGEHKDHVFLHLNHLSPEIVHSRLPGISETAKIFAGVDVTKEPIPVLPTVHYNMGGIPTNYHGQVIIKDGKNHNSVVKGLMSIGEAACVSVHGANRLGSNSLLDLVVFGRSAALKAAELIKPASPHKPVSEEALEKIISRFDKIRHSSGNISVADLRLKMQRTMQSHASVFRTQEVLDEGAEMISEIRSGYKDIKVNDKSLIWNSDLVEALELDNLLDQALVTVYSAAARKESRGAHAREDYPDRNDKEWMQHTLSGVDEAGKVVLDYKPVTLTTLSDEVKAIPPAKRVY
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Length
596 amino acids
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
65.291 kDa
Sequence
MTKAYNIIHHKFDVVVVGAGGAGLRSAFGMAKEGLNTACITKLFPTRSHTVAAQGGISAALGNMGEDDWRWHMYDTVKGSDWLGDQDAIEYMCKNAPDAILELEHYGVPFSRTEEGKIYQRPFGGMTTEYGKGKAAQRTCAAADRTGHAILHTLYQQSLKHKVQFFVEYFAIDLLMEDGECRGVVAWNLDDGSLHCFRAHNVVLATGGYGRAYFSATSAHTCTGDGGGMAIRAGLPLQDMEFVQFHPTGIYSAGCLITEGARGEGGYLVNANGERFMERYAPAAKDLASRDVVSRAMTIEIREGRGVGEHKDHVFLHLNHLSPEILHSRLPGISETAKIFAGVDVTKEPIPVLPTVHYNMGGIPTNYHGQVIIKDGKNHNSVVKGLMAIGEAACVSVHGANRLGSNSLLDLVVFGRSSALKAAELIKPASPHRSIKEESLEKIINRFDKVRHANGNILVAELRLKMQRTMQSHASVFRTQEVLDEGAGMISEIRSGYKDIKINDKSLIWNSDLVEALELDNLLDQALVTVYSAAARKESRGAHAREDYPDRNDEDWMKHTLSSIDEAGKVVLDYKPVTLTTLTDEVTAVPPVKRVY
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)
Length
596 amino acids
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
65.13 kDa
Sequence
MTKAYNIIHHKFDVVVVGAGGAGLRSAFGMAKEGLNTACITKLFPTRSHTVAAQGGISAALGNMGEDDWRWHMYDTVKGSDWLGDQDAIEYMCKNAPDAILELEHYGVPFSRTEEGKIYQRPFGGMTTEYGKGKAAQRTCAAADRTGHAILHTLYQQSLKHKVQFFVEYFAIDLLMEDGECRGVVVWNLDDGTLHCFRAHNVVLATGGYGRAYFSATSAHTCTGDGGGMAIRAGLPLQDMEFVQFHPTGIYSAGCLITEGARGEGGYLVNANGERFMERYAPAAKDLASRDVVSRAMTIEIREGRGVGEHKDHVFLHLNHLSPEILHSRLPGISETAKIFAGVDVTKEPIPVLPTVHYNMGGIPTNYHGQVIIKDGTNHNSVVKGLMAIGEAACVSVHGANRLGSNSLLDLVVFGRSSALKAAELISPASPHKPIKEASLEKIINRFDKVRHANGNILVADLRLKMQRTMQSHASVFRTQEVLDEGAGMISEIRNGYKDIKINDKSLIWNSDLVEALELDNLLDQALVTVYSAAARKESRGAHAREDYPDRNDGDWMKHTLSSIDEAGKIVIDYKPVTLTTLTDEISAIPPAKRVY
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
588 amino acids
Function
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
64.462 kDa
Sequence
MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMALRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEQGEDVVIPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGVLRDASESDVEGSLERLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPERDDANWLCHTLYQPQTESMTRRSVNMEPKLRPAFPPKIRTY
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Serratia sp. (strain ATCC 39006)
Length
588 amino acids
Function
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
64.536 kDa
Sequence
MNLPVREFDAVVIGAGGAGMRAALQISQMGLSCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAVLELEHMGLPFSRLDDGSIYQRPFGGQSRNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVMGCTAICIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMALRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKDVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQVLAVNEQGEDVVIPGLFAVGEIACVSVHGANRLGGNSLLDLIVFGRSAGMHLQESLEEQGATRDASNSDIEASLDRLNRWNSTRSGEDPVEIRKALQACMQHNFSVFREGDAMAKGLEELKVIRERLKNARLDDTSNDFNTQRIECLELDNLMETAYATAVSANFRTESRGAHSRFDYPDRDDDKWLCHTLYQPQTESMTRRKVNMQPKLRPAFPPKVRTY
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Escherichia coli O157:H7
Length
588 amino acids
Function
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
64.422 kDa
Sequence
MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESMTRRSVNMEPKLRPAFPPKIRTY
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Length
588 amino acids
Function
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
64.422 kDa
Sequence
MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESMTRRSVNMEPKLRPAFPPKIRTY
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Escherichia coli (strain K12)
Length
588 amino acids
Function
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
64.422 kDa
Sequence
MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESMTRRSVNMEPKLRPAFPPKIRTY
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Length
587 amino acids
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
65.438 kDa
Sequence
MSSIRVKQYDALIVGAGGAGLRAALEMAQSRQYKVAVVSKVFPTRSHTVSAQGGIAAALGNVVPDKPIWHMFDTVKGSDYLGDQDAIQYMCEQAPPSVYELEHYGLPFSRLDDGRIYQRAFGGHTRDFGKEMARRTCACADRTGHAMLHTLYQKNVEAGTHFYYEWYGIDLVRGAQGGIAGMIAMNMETSELVFFKSRATIFATGGAGRIYETTSNAYTNTGDGIGMVLRAGLPVQDMEFWQFHPTGIYGVGCLITEGARGEGGYLINKDGERFMERYSPHLKDLDCRDVVARSILQEVMAGGGVGPKKDHVLLKLDHLGEKVLRERLPGIIELSEKFANVDITKEPIPILPTCHYMMGGIPTNIHGQALTVDENGKDQIIEGLFAAGECACVSVHGANRLGTNSLLDLVVFGRAIGLHLEEALKTELKHRSENPDDIDAAIARLKRWEKPNNVENPALLRQEMRKAMSEDFGVFREEQKMKQGLERLQKLNERLQRAKLTDTSRTFNNARIEALELDNLMEVSYATAVSAQQRTESRGAHSRYDYKERDDANWLKHTVYFRDGHIAYRPVNMKPKGMDPFPPKSRD
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
sdhA
Protein
Succinate dehydrogenase flavoprotein subunit
Organism
Bacillus subtilis (strain 168)
Length
586 amino acids
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
65.152 kDa
Sequence
MSQSSIIVVGGGLAGLMATIKAAESGMAVKLFSIVPVKRSHSVCAQGGINGAVNTKGEGDSPWEHFDDTVYGGDFLANQPPVKAMCEAAPSIIHLLDRMGVMFNRTPEGLLDFRRFGGTQHHRTAYAGATTGQQLLYALDEQVRRYEVAGLVTKYEGWEFLGAVLDDDRTCRGIVAQNLTNMQIESFRSDAVIMATGGPGIIFGKSTNSMINTGSAASIVYQQGAYYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRVWTYKDGKPWYFLEEKYPAYGNLVPRDIATREIFDVCVNQKLGINGENMVYLDLSHKDPKELDIKLGGIIEIYEKFMGDDPRKLPMKIFPAVHYSMGGLWVDYDQMTNIPGLFAAGECDYSMHGGNRLGANSLLSAIYGGMVAGPNAVKYVNGLESSAEDMSSSLFDAHVKKEEEKWADIMSMDGTENAYVLHKELGEWMTANVTVVRHNDKLLKTDDKIQELMERFKKININDTTKWSNQGAMFTRQFSNMLQLARVITLGAYNRNESRGAHYKPDYPERNDDEWLKTTMAKHVSPYEAPEFEYQDVDVSLITPRKRDYSKKKVAK
Protein
Succinate dehydrogenase flavoprotein subunit: sdhA

Gene
SDHA
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Organism
Mesocricetus auratus
Length
551 amino acids
Function
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor.
Similarity
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Mass
60.045 kDa
Fragment
single
Sequence
DHEFDAVVVGAGGAGLRAAFGLSEAGFNTACGTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSTTEDGKIYQRAFGGQSLKFGKGGQAHRSCCVADRTGHSLLHTLYGRSLRYDTSYFVENFALDLLMENGECRGVIALCIEDGSIHRIRAKNTVIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFIQFHPTGIYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRSWGPEKDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLKHVNGQDQVVPGLYACGEAACASVHGAIRLGANSLLDLVVFGRACALSIAESCSPGDKVPPIKANAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQSHAAVFRVGSVLQEGCEKISQLYGELKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRVDEYDYYXA
Protein
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial: SDHA

Gene
sdhA
Protein
L-serine dehydratase, alpha chain
Organism
Peptoniphilus asaccharolyticus
Length
292 amino acids
Similarity
Belongs to the iron-sulfur dependent L-serine dehydratase family.
Mass
30.77 kDa
Sequence
MLNTAREIIDVCNERGIKIYDLVLEEEIKNSHTTEEEIRKKLDAVIDVMHASATKNLTQSDVTEYKMIDGFAKRTYEYANSGKSIVGDFLAKAMAMAFSTSEVNASMGKIVAAPTAGSSGIMPAMLVAATEKYNFDRTTIQNGFLTSIGIGQVITKYATFAGAEGGCQAECGSASAMAAAALVEMLGGTVEQALHAASITIINVLGLVCDPIAGLVQYPCTFRNASGVINAFISADLALAGVESLVPFDEVVIAMGEVGNSMIEALRETGLGGLAGSKTGQKIRRDFLKEGD
Protein
L-serine dehydratase, alpha chain: sdhA

Gene
sdhA
Protein
Probable L-serine dehydratase, alpha chain
Organism
Lactobacillus sakei
Length
209 amino acids
Similarity
Belongs to the iron-sulfur dependent L-serine dehydratase family.
Mass
20.887 kDa
Fragment
single
Sequence
DIMLEAVQNAIATNEVNASMGIICATPTAGSAGTLPGILSVITKQLSLDRDAQIRFLFCASAFGMVVANDAMIAGATGGCQAEVGSASAMGAAAAVEAAGGTHQQSSEAFAMAMSNLLGLVCDPVAGLVEVPCVKRNVIGSVNALTSADMALAGLVSKIPADEVISAMKSIGENLPSTLRETGLGGLAATPTGIALKMQIFGQDMSIDK
Protein
Probable L-serine dehydratase, alpha chain: sdhA