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sdc4-b

Gene
sdc4-b
Protein
Syndecan 4-B
Organism
Xenopus laevis
Length
205 amino acids
Function
Cell surface proteoglycan that bears heparan sulfate. Regulates non-canonical Wnt signaling, being necessary and sufficient for fibronectrin-mediated translocation of dvl2/dsh to the plasma membrane. Required for proper convergent extension movements during gastrulation, which shape the neural plate, and for subsequent neural tube closure.
Similarity
Belongs to the syndecan proteoglycan family.
Mass
22.929 kDa
Sequence
MNRLLLLLALVLSGVAAESIRETETMDPTSMLEYESSGSFTDEVFVDEDDDDDYEDGVDYEIDSESDNDEDYSGSGDDDFDDEDNVEDEDEEETTTLGNQIPEHDFDETKTGRKFDTFNENNEIDNDIRHPAKPKTLEPSNEIPMASIGSSGFFQRTEVIVAIIAGTLVGLVVAVSFIVFLVIRRNQNGDLVKKPIYKKTSTMEV