Protein
Probable E3 ubiquitin ligase complex SCF subunit scon-2
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
Component of the SCF(scon-2) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.
Similarity
Belongs to the WD repeat MET30/SCONB/SCON-2 family.
Sequence
MSSVLMSKTVTPFLREHIPSIYAPIGKPGNQETARAENPNSKYCYRHHPDSKCRRAADKAKMVMIQSELDKLTSADQQAVTHVWSLFSAAPARHRDLMLQGILSQLCFPQLSFVSREVNEALKIDFISALPVELAQKVLCYLDTVSLTKAAQVSQRWRTLADSDAVWVRMCEQHVNRKCTKCGWGLPLLERKKLRNYTRQRQLAKGGPQGRVTELADSHDSQDRSVNQHGKRPAAEAEEEDPIKKRQCMAAAEASKAVTQPKTRSWKAVYRDRWQVSYNWKNSRYKLSVLKGHENGVTCLQLDDNILATGSYDTTIKIWNIETEECIRTLVGHTAGIRALQFDDSKLISGSLDHTIKVWNWHTGECLSTFAAHTDSVISVHFDGHLLASGSSDKTVKIFDFNSKETYCLKGHSDWVNSTHVDIKSRTVFSASDDTTIKLWDLDTRQVIRTYEGHVGHVQQVLILPPEYEPDEEVLNGASQDNQDAMSVSSGGSGSPSMSHAQIERAGSPGSHSSSHNLLPSSLPSGDEDVRHLYGSAFVADESRPLPPRYFMTGGLDSTMRLWDSATGRCLRTLFGHLEGVWSLAGDTIRVISGANDGMVKTWEPRSGKCDATYTGHCGPVTCVGLSDSLMASGSEDGTIRLHSFKPCRQ