scn4aa

Sodium channel protein type 4 subunit alpha A

1892 amino acids

Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.

Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily.

213.099 kDa

MATILPPPGTALFRHFTRQSLATIERLKEETLIAPKAGAHEEEEPPTPNPDLEAGKSLPMIFGDPPSELLGTPLEDIDPFYKAQKTFVVVTKGNTIYRFNAEPACYILSPFSLVRRGAIKILIHSLFSTLIMITILSNCVFMTMSNPPAWSKTVEYVFTGIYTFEATVKVLSRGFCVGPFTFLRDPWNWLDFMVISMAYITEFVDLGNVSALRTFRVLRALKTITVIPGLKTIVAALIQSVKKMVDVMILTVFALAVFALVGLQLFMGNLRHKCIRWPIANETASELFNGTVFNDTLSYNDTTWLNDTLDSNSTFDFTEYIENAENQYFLEGSKDALLCGNSTDAGKCPEGYLCMKAGRNPNYGYTSFDSFGWAFLALFRLMTQDNWESLFQLTLRAAGQTYMLFFVVVIFLGSFYLINLILAVVAMAYDEQNQASQQEAKEKEEEFQRLLEQLKNQEQAQVLGSRASLTSKKSVSLTGSDVADDEQSLENNEALKDCNGRPIPRLIIRAPTMKESAADYELREKEESSVHSVLHLDEPGLRERSASVATAAASVATAAASVATAAAMEELEEAQRPCPPIWYRFADIFLKWNCCEKWVVFKKWVHFVVMDPFVDLAITICIVLNTLFMAMEHYPMTEEFDYMLSVGNLVFTGIFAAEMFFKLIAMDPYYYFQVGWNIFDSIIVTLSLVELGLANVQGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKISSDCELPRWHMNDFFHSFLIVFRILCGEWIETMWDCMEVAGAGMCLVVFMMVMVIGNLVVLNLFLALLLSSFSGDNLSVGDDDGELNNLQIAIGRITRGGNWLKAFLIGTVQRVLGREPQKPAEEDPADEGEGKTEGMEMNHLDGFKLADGIANCLVGGQPSGVTLDGESSITVPIALGESDSENPSEDDDDQEDDVDSEVTCEENEHHSDGVEDEFGVLQHVKLMGALTDGDSSVCSTVDYQPPEPEVQEEEEEEPDLVEPEACFTDNCVKRWPCLNVDISQGKGKKWWNLRKTCFTIVEHDWFETFIIFMILLSSGALAFEDIYIERRRTVKIVLEFADKVFTFIFVIEMLLKWVAYGFKTYFTNAWCWLDFFIVDISLISLSANLMGFSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIFNVLLVCLIFWLIFSIMGVNLFAGKFYRCINTTTAELFPISVVNNKSDCVALQEATQEARWVNVKVNYDNVAKGYLSLLQIATFKGWMDIMYPAVDSREVEEQPSYEINLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGDKDIFMTEEQKKYYEAMKKLGSKKPQKPIPRPANLIQGLVFDFISQQFFDIFIMVLICLNMVTMMVETDDQSPAKEDFLFKVNVAFIVVFTGECTLKLFALRHYFFTNGWNIFDFIVVILSIAGTMLSDIIEKYFVSPTLFRVIRLARIGRILRLIKGARGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGMSNFAYVKKEAGINDMFNFETFGSSIICLFQITTSAGWDTLLLPMLNKEPPDCDPAFENPGTDVKGNCGNPMMGMVFFCSYIIISFLVVVNMYIAIILENFNVAQEESGDVLCEEDFEMFNETWEKFDTGGTQFIEYSQLSDFCDALQEPLRVAKPNRQRLIEMDLPLVIGDRIHCVDVLLAVTQEVLGDTIEMVAMRESIEAKFNLNNPTSASYAPITTTVRQKEEDMAAVVIQRAYRNHLHKRGIHHAAYIQRSKTGRKAASEDAPEKEGLLAKKMGALYGSDADLADEVEGLRRRPDPQTRCSGARCSPEPPEPNIILVPVEITNELLLHSAPSQQSSPTQTILRETNV

scn4aa

Sodium channel protein type 4 subunit alpha A

1863 amino acids

Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.

Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily.

210.434 kDa

MATILPPPGTAMFRHFTPQSLAKIERLKEETKKAAEVGPREEEEPPTPNPDLEAGKGLPRIYGEPPAELLSTPLEDLDPFYKAQKTFVVITKGNTIYRFNAEPACYILSPFSRVRRGAIKILIHSLIMITILSNCVFMTMSNPPAWSKTVEYVFTGIYTFEATVKVLSRGFCVGPFTFLRDPWNWLDFMVISMAYITEFVDLGNVSALRTFRVLRALKTITVIPGLKTIVAALIQSVKKMVDVMILTVFALSVFALVGLQLFMGNLRHKCIRWPVAANQSAFEPFNSTVGNDTTGLNDTLFSNITFDFTEYIENAENQYFLPGSADALLCGNSSDAGRCPEGYECMKAGRNPNYGYTSFDSFGWAFLALFRLMTQDCWENLFQQTLRAAGKTYMLFFVVVIFLGSFYLINLILAVVAMAYEEQNQASQQEAREKEEEFQWLLEQLKNQEQAQVLGSRASPTSEKSVSLTTSDAPDEDQSLENDEALKDCNGRFIPRLIVRAPTMKESAADYESGEKVEGSTHSRLHVEDAGLKQRSASAVTVLTAAAVEELEEAQRPCPPIWYKFANMFLKWNCCQPWAVFKEWVHFVVMDPFVDLAITICIVLNTLFMAMEHYPMTQEFDYMLSVGNLVFTGIFAAEMFFKLIAMDPYYYFQVGWNIFDSIIVTLSLVELGLANVQGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGSSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKISTECELPRWHMNDFFHSFLIVFRILCGEWIENMWACMEVAGAGMCLVVFMMVMVIGNLVVLNLFLALLLSSFSGDNLSIGEDDGEMNNLQIAIGRITRGGNWLKTLVIRTVLQLLGREQGKPAEEDPAEEGEQKPERIEMNHLDQLKTADGIANCLVGRQPSGTAADGESVINVPIALGESDSEHQSEGDDYQEDDVDSESTCEENEHGSNSMEDGFGVLQHVKLMGALTDGESSVCSTADYRPPEPETLEEEEEEPEPLEPEACFTDNCVKHWPCLNVDVTQGQGKKWWNLRKTCFTIVEHDWFETFIIFMILLSSGALAFEDIYIERRRTVKIILEFADKVFTFIFVLEMVLKWVAYGFKTYFTNAWCWLDFFIVDISLISLSANLMGLSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIFNVLLVCLIFWLIFSIMGVNLFAGKFYHCINTTTQELFPISVVNNKSDCMAVQEATQEARWVNVKVNYDNVGKGYLSLLQIATFKGWTAIMYAAVDSREVEEQPSYEINLYMYIYFVIFIIFGAFFTLNLFIGVIIDNFNQQKRKLGDKDIFMTEEQKKYYEAMKKLGSKKPQKPIPRPTNLIQGMVFDFISQQFFDIFIMVLICLNMVTMMVETDDQSPEKEDFLFKVNVAFIVVFTGECMLKLIALRQYFFTNGWNIFDFVVVILSIAGTMLSDLIEKYFVSPTLFRVIRLARIGRILRLIKGARGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGMSNFAYVKKEAGIDDMFNFETFGSSIICLFQITTSGGWDQILLPILNKEPPDCDPTLENPGTDVKGNCGNPMVGMMFFCSYIIISFLVVVNMYIAIILENFNVAQEESGDALCEEDFEMFNETWEKFDTGGTQFIEYSQLSDFCDTLQEPLRVAKPNRLRLIEMDLPLVIGDRIHCVDVLLAVTQEVLGDTIEMVAMRESIEAKFNLNNPTSVSYAPITTTVRQKEEEMAAVVIQRAYRNHLHKRGIHHAAYIQRSKTGRKADSEDAPEKEGLLAEKMGALYGREAEGRERAPDPETPPRCSGARCGPEPPEPNVIVVPVEITNEFLLHSAPPTHTSYPRRQT

scn4aa

Sodium channel protein type 4 subunit alpha A

1829 amino acids

Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.

Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.4/SCN4A subfamily.

207.737 kDa

MARLLPPTGTSVFRRFTPESLVEIERLIQEKSTREELEGAEEEPQAPSSDLEAGKCLPMIYGDPPGDLLNTPLEDIDPFYKTQKTFIVISKGNTIFRFSSEPAMFCISPFSIVRRGAIKILIHSLFSMFIMITILSNCVFMTMSNPPAWSKTVEYVFTGIYTFEATVKVLSRGFCIGPFTFLRDPWNWLDFMVISMAYVTEFVDLGNVSALRTFRVLRALKTITVIPGLKTIVGALIQSVKKMIDVMILTIFALAVFALIGLQLFMGNLRQKCIRWPILNSTIFDVYNSNMVNDTTLNVTDTFDFKAYINNEENQYFLEGSLDALLCGNSSDAGRCPEGYTCMKAGRNPNYGYTSYDNFGWAFLALFRLMTQDFWENLFQLTLRAAGKTYMIFFVVVIFLGSFYLINLILAVVAMAYDEQNEATLAEARDKEEEFQRLLEQLKNQETGSKASLASQKTQSRGSNRTGSLHDLADEDVIKDCNGRIVPRLIVNRVSSNKELSAEEDQKSLSSKHSMQYLDQPKLSKRTASALSVLTATMEGLEDAQRPCPPGWYKFADMFLKWDCCAPWILFKKWVHFVVMDPFVDLGITICIVLNTLFMAMEHYPMSPHFEHVLSVGNLVFTGIFTAEMVFKLIAMDPYYYFQVGWNIFDSIIVTLSLVELGLANVQGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKDCVCKISEDCELPRWHMNDFFHSFLIVFRILCGEWIETMWDCMEVAGASMCLIVFMMVMVIGNLVVLNLFLALLLSSFSGDNLSGGDDDGEMNNLQIAIGRITRGIDWVKALVASMVQRILGKKPDNTKEEGEGDIELYALNHLDEGKMADGLTNCLSPTLTVPIARCESDVEEDEDSESSDEEDAKATLNDGDSSVCSTVDYQPPEPEPEPEEVEEEEPEPEEPEACFTEGCIRRCACLSVDITEGWGKKWWNLRRTCFTIVEHDYFETFIIFMILLSSGALAFEDINIERRRVIKTILEYADKVFTYIFIVEMLLKWVAYGFKTYFTNAWCWLDFLIVDVSLVSLTANLMGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALVGAIPSIFNVLLVCLIFWLIFSIMGVNLFAGKFYHCINTTTEERIPMDVVNNKSDCMALMYTNEVRWVNVKVNYDNVGLGYLSLLQIATFKGWMDIMYAAVDSREVDEQPSYEINLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKSKFGGKDIFMTEEQKKYYNAMKKLGAKKRPKPIPRPSNIIQGLVFDFISKQFFDIFIMVLICLNMVTMMIETDDQSAEKEYVLYQINLVFIVVFTSECVLKLFALRQYFFTIGWNVFDFVVVILSIAGLMLSDIIEKYFVSPTLFRVIRLARIGRVLRLIRGAKGIRTLLFALMMSLPALFNIGLLLFLIMFIFSIFGMSNFAYVKKQAGIDDIFNFETFGGSIICLFEITTSAGWDGLLLPILNSGPPDCDPDFENPGTDVRGNCGNPGMGIMFFCSYIIMSFLVVVNMYIAIILENFNNAQEESGDPLCEDDFDMFDETWEKFDVDATQFIEYDRLFDFVDALQEPLRIAKPNRLKLISMDIPIVNGDKIHSQDILLAVTREVLGDTIEMDAMKESIEAKFIMNNPTSASFEPIITTLRRKEEERAAIAVQRIYRRHLLKRAIRYACFMRRSKRKVRNPNDNEPPETEGLIARKMNTLYGSNPELAMALELETRPMRPNSQPPKPSQVTQTRASVTFPRPQGQLILPVELTSEVILRSAPITHSLNSSENATTIKESIV