Protein
DNA gyrase inhibitor 1
Organism
Dickeya dadantii (strain 3937)
Function
Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
Similarity
Belongs to the DNA gyrase inhibitor family.
Sequence
MDYNVQHVDKRHAAGFHLVGPWEQTVPQGFEQLMKWVDEHAVQPLEWVAVYYGNPQETPPEKLEADTVVSVSADFHLPADGEGAITTEIAAGQYAIARVRVSNDDFGMSWQAFFAALLGDGKTIDPARACFEVYLNDGYSDGFWDIDMHIPVQ