Protein
Putative oxidoreductase SadH
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Function
Required for maintaining the appropriate mycolic acid composition and permeability of the envelope on its exposure to acidic pH.
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Sequence
MSSFEGKVAVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLAQALGAQVKSDRLDVAEREAVLAHADAVVAHFGTVHQVYNNAGIAYNGNVDKSEFKDIERIIDVDFWGVVNGTKAFLPHVIASGDGHIVNISSLFGLIAVPGQSAYNAAKFAVRGFTEALRQEMLVARHPVKVTCVHPGGIKTAVARNATVADGEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAKGQARVVVGLEAKAVDVLARIMGSSYQRLVAAGVAKFFPWAK