Protein
Autotransporter adhesin SadA
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function
Involved in cell aggregation, biofilm formation, and adhesion to human intestinal epithelial cells.
Similarity
Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
Sequence
MNRIFKVLWNAATGTFVVTSETAKSRGKKNGRRKLAVSALIGLSSIMVSADALANAGNDTGDGVTPTGTQTGGKGWIAIGTDATANTYTNVDGASAAMGYKASAMGKWSTAIGSYSQSTGDSSLALGVKSVSAGDRAIAMGASSSASGSYSMAMGVYANSSGAKSVALGYKSVASGATSSALGYQATASGDDSAAFGNGAKAIGTNSVALGSGSVAQEDNSVAVGNSTTQRQITYVAKGDINSTSTDAVTGAQIYSLSQSVADRLGGGASVNSDGTVNAPLYEVGTGIYNNVGSALSALNTSITNTEASVAGLAEDALLWDESISAFSASHTGNASKITNLAAGTLAADSTDAVNGSQLFDTNEKVDKNTADIATNTGSINQNTADITANTDSINQNTTDIAANTTSINQNTTDIATNTTNINSLSDSVTTLTDDALLWDAASGAFSAKHNGSDSKITNLAAGTLAADSTDAVNGSQLFDTNEKVDQNTADITTNTNSINQNTTDIATNTTNINNLSDSITTLTDDALLWDAASGAFSANHNGSASKITNLAAGTLAADSTDAVNGSQLFATNENVSQNTADITTNTNSINQNTTDIATNTTSINNLSDSITTLTDDALLWDAASGTFSASRSGSASKITNLAAGTLAADSTDAVNGSQLYETNQKVDQNTSAIADINTSITNLSSDNLSWNETTSSFSASHGSSTTNKITNVAAGELSEESTDAVNGSQLFETNEKVDQNTTDIAANTTNITQNSTAIENLNTSVSDINTSITGLTDNALLWDEDTGAFSANHGGSTSKITNVAAGALSEDSTDAVNGSQLYETNQKVDQNTSAIADINTSITNLGTDALSWDDEEGAFSASHGTSGTNKITNVAAGEIASDSTDAVNGSQLYETNMLISQYNESISQLAGDTSETYITENGTGVKYIRTNDNGLEGQDAYATGNGATAVGYDAVASGAGSLALGQNSSSSIEGSIALGSGSTSNRAITTGIRETSATSDGVVIGYNTTDRELLGALSLGTDGESYRQITNVADGSEAQDAVTVRQLQNAIGAVTTTPTKYYHANSTEEDSLAVGTDSLAMGAKTIVNADAGIGIGLNTLVMADAINGIAIGSNARANHANSIAMGNGSQTTRGAQTDYTAYNMDTPQNSVGEFSVGSEDGQRQITNVAAGSADTDAVNVGQLKVTDAQVSRNTQSITNLNTQVSNLDTRVTNIENGIGDIVTTGSTKYFKTNTDGADANAQGADSVAIGSGSIAAAENSVALGTNSVADEANTVSVGSSTQQRRITNVAAGVNNTDAVNVAQLKASEAGSVRYETNADGSVNYSVLNLGDGSGGTTRIGNVSAAVNDTDAVNYAQLKRSVEEANTYTDQKMGEMNSKIKGVENKMSGGIASAMAMAGLPQAYAPGANMTSIAGGTFNGESAVAIGVSMVSESGGWVYKLQGTSNSQGDYSAAIGAGFQW