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sGDLP

Gene
sGDLP
Protein
Longicornsin
Organism
Haemaphysalis longicornis
Length
78 amino acids
Function
Has antibacterial activity against the Gram-positive bacteria S.aureus ATCC2592 (MIC=0.8 ug/ml), S.aureus 6A (MIC=0.8 ug/ml) and S.aureus 15A (MIC=1.6 ug/ml), and against the Gram-negative bacteria E.coli ATCC 25922 (MIC=3.2 ug/ml), E.coli 23A (MIC=6.4 ug/ml), E.coli 27A (MIC=6.4 ug/ml), P.aeruginosa 3A (MIC=3.2 ug/ml), P.aeruginosa 7A (MIC=0.8 ug/ml) and H.pylori NCTC11637 (MIC=6.4 ug/ml). Has antifungal activity against C.albidus ATCC2002 (MIC=25.6 ug/ml). Very low hemolytic activity against rabbit erythrocytes.
Similarity
Belongs to the invertebrate defensin family. Type 2 subfamily.
Mass
8.837 kDa
Sequence
MAESTTTCFLLLVTGYVTAVMSEEAHLRSRRDFGCGQGMIFMCQRRCMRLYPGSTGFCRGFRCMCDTHIPLRPPFMVG