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rumA1

Gene
rumA1
Protein
Ruminococcin-A
Organism
Blautia hansenii
Length
47 amino acids
Function
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. Ruminococcin A is a broad spectrum bacteriocin exhibiting activity against a wide range of pathogenic clostridia and B.longum (By similarity).
Similarity
Belongs to the type A lantibiotic family.
Mass
5.346 kDa
Sequence
MRNDVLTLTNPMEENELEQILGGGNGVLKTISHECNMNTWQFLFTCC

Gene
rumA1
Protein
Ruminococcin-A
Organism
Ruminococcus gnavus
Length
47 amino acids
Function
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. Ruminococcin A is a broad spectrum bacteriocin exhibiting activity against a wide range of pathogenic clostridia and B.longum.
Similarity
Belongs to the type A lantibiotic family.
Mass
5.36 kDa
Sequence
MRNDVLTLTNPMEEKELEQILGGGNGVLKTISHECNMNTWQFLFTCC