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rsc9

Gene
rsc9
Protein
Chromatin structure-remodeling complex subunit rsc9
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
780 amino acids
Function
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes.
Similarity
Belongs to the RSC9 family.
Mass
87.995 kDa
Sequence
MSQVIQGAVEEPVYSNKSLTNENDSFLSLIESFSQERGVPIDINPKIGRKPILLYELYKKVIKRGGYDAVSATEDGWTNIAEEFNQSDPARSAGILQNVYFKYLISWEIHDHWHLLLPPPSTLELSENRQNVLERVKVFNSCSPPKPTNPITIIDNDKTHSFKKFYKSLVKEDEENGIEKKINEAMNSSASQPLPNSTNFASTTFPSVPFHPLPVDSGLQKYIDRNSNLTPPALGAGVPGPPLLVRVALALKSQQDKEVDWAIGHLIKISFERHQEFKLERLPSLAECLVYSLGFQVTKAKQVSDLTDISLCMDRAIGIALVLRNSVLSVENAKHVAQTKLVISVLEASIRCAKTFNNLEFLHYCLDISEMISSYLHVEDEKNVFYLALCEFLNSSDYSILIATLRTLARLALNDRNNRLLQDLKSNVIANIIALVETDNEEIVAAALDFLYQYTTYRTNTSNLLASQEAWMLVDQLIRLMMYQAQERFMTVTIENSESNPAVKHEATSSISLPMEELQQLVAMREPERSVKWMRCCFEPSSDDYVLQTDIWQLYCSDMERAQGPNVMGISPADFIKVSSHAFYNARAMTVSTPQLPVEYVINGIKRRKFPTSVNGMRYQPCRWCLDSGKECGELLLGTPLLHSHLQEMHIFPQILETGKCRWSDCKYEIQRLTPASELSHYQLLSHIVTHLHDDSLETLVEGRKLSPSREFRIPLLLTAVDDQGDATGIALTATLVLRNLVRSKQGKMLFSAIESRVLEVSSLNPAVAPYVSEMLLGQI

Gene
RSC9
Protein
Chromatin structure-remodeling complex subunit RSC9
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
581 amino acids
Function
Component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. This subunit plays a role in transcriptional response to stress. It is involved in both repression and activation of mRNAs regulated by the target of rapamycin (TOR) kinases, and in the synthesis of rRNA.
Similarity
Belongs to the RSC9 family.
Mass
65.218 kDa
Sequence
MNSLASNTPLNGTPVSEAPATSSEPVNMFETMVANPIKVSRLQSNGVLTGPAANTKSIHYSLANFNVFQSLPKETARGVDDLTRMEMALLSGIPEEIKWSLKKYLTYSNKAPYMISLRTLPDLLPLFKTFILPLERIVEGLNKSSICDSKAMDSLQMGLNALLILRNLAQDTDSVQILVKDREIKSFILFILKKFQCVATGDNKWQLYEGNATFFNELTHYTLDLMEAISSYIAPAMKDDHYFQTLVSILNYTKDRYMVISILRSLSRLLVRSKANEESAADNLDHKTLSLIVSFLLLECDSELIIASLDFLYQYILPGSQRITELFKSKECSLILEATLPNLLSYNIATPDYHLLQKHKIRLIKRLKPPAPKEPPNLSEDLFQQLFKLNEPLRSTAWLRCCFEPVQEAEFTQISLWRSYESKFGQPVRESGRKLLPAVEFIKNVSNAFNNAAAIVITDPVTGKKRFVIKGIQPRFKALGIADGERESQVPISALKSKFLNDSKEITPARQNSIPEVKFPQELSDVSKVACTFLCLLSNDTDDGAGSAFCQRIRPLVLHKLADIPPLTLALSEYMENTSGL