Protein
RNA polymerase sigma-54 factor
Organism
Sinorhizobium fredii (strain NBRC 101917 / NGR234)
Function
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes (nif operon), glnA and dctA for dicarboxylate transport. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator proteins NifA, NtrC, or DctD for the expression of the regulated proteins.
Similarity
Belongs to the sigma-54 factor family.
Sequence
MALSASLHLRQSQSLVMTPQLMQSIQLLQMTHLELGQFIAQEVEKNPLLEFQSADEAGFGSDRPERDETGLTAEAGGAEESVDHGDLYDSATTSPGERLSTELDADFANVFQDDTAPQRADAPELLGQWKSMPGAGGSNDGEGYDLDDFVAGRKTLRETLIEQVAFAFAAPADRLIAQHLIDQLDEAGYLHAEIAETAARLGASAADVTRVLLVLQQFDPPGVFARTLSECLAIQLRLRNRLDPAMEALVANLELLARRDFASLKKICGVDEEDLIEMLAEIRKLDPKPGTSFETSVTEAIIPDVVVRSAPDGGWLVELNPDALPRVLVNHDYFAEISRHSQKNSAEQAFLSECMQNANWLTRSLDQRARTILKVASEIVRQQDAFLVHGVDHLRPLNLRIVADAIKMHESTVSRVTSNKYILTPRGLFELKYFFTVSIGSAENGDAHSAESVRHRIRTMISQESADAVLSDDDIVDILKRAGVDIARRTVAKYREAMNIPSSVQRRREKRALAKAAGF