RNFT1

E3 ubiquitin-protein ligase RNFT1

435 amino acids

E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis.

49.71 kDa

MPLFLLSLPTPPSASGHERRQRPEAKTSGSEKKYLRAMQANRSQLHSPPGTGSSEDASTPQCVHTRLTGEGSCPHSGDVHIQINSIPKECAENASSRNIRSGVHSCAHGCVHSRLRGHSHSEARLTDDTAAESGDHGSSSFSEFRYLFKWLQKSLPYILILSVKLVMQHITGISLGIGLLTTFMYANKSIVNQVFLRERSSKIQCAWLLVFLAGSSVLLYYTFHSQSLYYSLIFLNPTLDHLSFWEVFWIVGITDFILKFFFMGLKCLILLVPSFIMPFKSKGYWYMLLEELCQYYRTFVPIPVWFRYLISYGEFGNVTRWSLGILLALLYLILKLLEFFGHLRTFRQVLRIFFTQPSYGVAASKRQCSDVDDICSICQAEFQKPILLICQHIFCEECMTLWFNREKTCPLCRTVISDHINKWKDGATSSHLQIY

rnft1

E3 ubiquitin-protein ligase RNFT1

419 amino acids

E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis.

47.191 kDa

MKLRAQFDRGTYSESKGSFKLRDSLDPMQPEPSSREGNGLSLTLQPELLARMPGAGSSSGTETGEDVRVPMGSSSGSTNGRGATSRRMRTASHSHSHTHGHGHSHEHESDSGESDLESGESSSSISELRYLLRWLKKSLPFIVILCAKLVIQHALGLAVAVGLFTTFMYVNKSIQTQVFLHDRRTNLHCAWLLLFLTSSSLLVFYTFHTQSLYRCLFFANATIDYHNFWEVLWSVGVTNFILKFIFMGFKCLILLVPCPLMTYRRRGQWYMLIEEVGQLYQVIAPVPLWFRYLVSYDEMDTSVGLTLGILLALLYLIMKLLALYGLSGSLQKTLRTFFSPEVNGAPASPAQIREAGDICPICQADFKQPRVLVCQHIFCEECIAQWLNQERTCPLCRTVITDKVHKWKDGATSAHLQIY

rnft1

E3 ubiquitin-protein ligase RNFT1

416 amino acids

E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis.

47.122 kDa

MKHRPVHERQSSTESKNLKETTQLIMQSSSDHTHHQLGSNDSPSACMSLPVPQLSAEGSCTVGDVTVDLSSQDSQHVARSNSRRVRPSTHGRSPSRHGHTHSHDASGPEDANDDSREQSNSISEVFHLYKWLEKSFPYILIFSAKLVVQHITGISVGIGLLTTFLYANKCIVNQVFLRDKCSKLQCLWVLVFLLFSSFLLYYTFSSQALYYSLVFMNPSLGPLHFFDALWVVGITDFIGKFFFMGLKCIILLVPSFVMSHKSKGYWYMALEELAQCYCTLVSTPVWFRYLIDYGNLDSGAEWHFGILLALLYLILKILIIFGQRKTSSDCLRLFLSQPNYGTTATKRQCSEADGMCAICQAEFTKPIALICQHVFCEECISSWFNKEKTCPLCRTLISNHSHKWKDGATSLQLRIF

rnft1

E3 ubiquitin-protein ligase RNFT1

416 amino acids

E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis.

47.03 kDa

MKHRPVHERQCSTETKNWKENTQLIMQSSSGHTHHQPGSNDSPSVCMSLPVPQLSAEGSCTAGDVTIDLSSPESHHGARSSSRRVRPGNGRSLSRHGHTHSHDANGPEDANDADSREQSNSISEVFHFYKWLEKSFPYILIFSAKLVVQHITGISVGIGLLTTFLYANKCIVNQVFLRDKCSKLQCLWILVFLLFSSLLLYYTFSSQALYYSLVFMNPSLGPLHFFDALWVVGITDFIGKFFFMGLKCIILLVPSFVMSHKSKGYWYMALEEVAQCYCMLVSTPVWFRYLIDYGNQNSGAEWHFGILLALLYLILKLLIIFGQRKTSSNSLRLFLTQPNYGAAATKSQCSEVDGMCAICQAEFIKPIVLVCQHVFCEECISLWFNKEKTCPLCRTVISNQSHKWKDGATSLQLRIF

Rnft1

E3 ubiquitin-protein ligase RNFT1

395 amino acids

E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis.

45.277 kDa

MQASCNQLHDPPGTAHEDAAASPCGHSRSTEGSLHPGDVHIQINSGPKEYSENPSSRNPRSGVCTCAHGCVHGRFRSYSHSEARPPDDFATESGEHGSGSFSEFRYLFKWLQKSLPYILILGIKLVMQHITGISLGIGLLTTFMYANKSIVNQVFLRERSSKLRCAWLLVFLAGSSVLLYYTFHSQSLHYSLIFLNPTLEQLSFWEVLWIVGITDFILKFFFMGLKCLILLVPSFIMPFKSKGYWYMLLEELCQYYRIFVPIPVWFRYLISYGEFGNVTTWSLGILLALLYLILKLLDFFGHLRTFRQVLRVFFTRPSYGVPASKRQCSDMDGICTICQAEFQKPVLLFCQHIFCEECITLWFNREKTCPLCRTVISECINKWKDGATSSHLQMY