Protein
Probable E3 ubiquitin-protein ligase RNF144A-B
Function
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes ube2l3 and ube2l6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Similarity
Belongs to the RBR family. RNF144 subfamily.
Sequence
MSSSRYEPSWDVDLAPLLSCKLCLGEFPLEQMTTISQCQCIFCSLCLKQYVELLIKEGLETAISCPDSACPKQGHLLENEIECMVAGEVMQHYKRLQFEREVLLDPCRTWCPSSSCQAVCQLNEAEVQLPQPVQCPECSLRFCSACRADCHTGQACQEMLPITTFLPGENGSNLKSQEDEAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLLIHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCKRGDDDPLPT