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rmlC

Gene
rmlC
Protein
dTDP-4-dehydrorhamnose 3,5-epimerase
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
202 amino acids
Function
Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Involved in the biosynthesis of the dTDP-L-rhamnose which is a component of the critical linker, D-N-acetylglucosamine-L-rhamnose disaccharide, which connects the galactan region of arabinogalactan to peptidoglycan via a phosphodiester linkage.
Similarity
Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
Mass
22.314 kDa
Sequence
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT

Gene
rmlC
Protein
dTDP-4-dehydrorhamnose 3,5-epimerase
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
202 amino acids
Function
Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Involved in the biosynthesis of the dTDP-L-rhamnose which is a component of the critical linker, D-N-acetylglucosamine-L-rhamnose disaccharide, which connects the galactan region of arabinogalactan to peptidoglycan via a phosphodiester linkage.
Similarity
Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
Mass
22.314 kDa
Sequence
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT

Gene
rmlC
Protein
dTDP-4-dehydrorhamnose 3,5-epimerase
Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length
201 amino acids
Function
Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Involved in the biosynthesis of the dTDP-L-rhamnose which is a component of the critical linker, D-N-acetylglucosamine-L-rhamnose disaccharide, which connects the galactan region of arabinogalactan to peptidoglycan via a phosphodiester linkage.
Similarity
Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
Mass
22.241 kDa
Sequence
MTARELSIAGAWEITPVLRTDSRGLFFEWFTDAGFTEFAGHQFDMRQANCSVSARGVLRGVHFAQVPPSQAKYVTCVRGAVFDVVVDIRVGSPTFGQWDAVLLDDKDRRSIYISEGLGHAFLALDDDSTVMYLCSAPYAPQREHTVRPTDFGIEWPEVPELILSDRDAQAPSLAEAQAAGVLPTWADCQAFVETLRRNLVS

Gene
rmlC
Protein
dTDP-4-dehydrorhamnose 3,5-epimerase
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Length
185 amino acids
Function
Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
Similarity
Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
Mass
21.678 kDa
Sequence
MAEFRFIKTSLDGAIIIEPEVYTDERGYFMETFNEAIFQENGLEVRFVQDNESMSVRGVLRGLHFQREKPQGKLVRVIRGEIFDVAVDLRKNSDTYGEWTGVRLSDENRREFFIPEGFAHGFLALSDECIVNYKCTELYHPEYDSGIPWDDPDIGIDWPLEMVDDLIISEKDRNWKPLRENPVYL

Gene
rmlC
Protein
dTDP-4-dehydrorhamnose 3,5-epimerase
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
181 amino acids
Function
Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
Similarity
Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
Mass
20.766 kDa
Sequence
MKATRLAIPDVILFEPRVFGDDRGFFFESYNQRAFEEACGHPVSFVQDNHSRSARGVLRGLHYQIRQAQGKLVRATLGEVFDVAVDLRRGSPTFGQWVGERLSAENKRQMWIPAGFAHGFVVLSEYAEFLYKTTDFWAPEHERCIVWNDPELKIDWPLQDAPLLSEKDRQGKAFADADCFP