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ribE

Gene
ribE
Protein
Riboflavin synthase
Organism
Photobacterium leiognathi
Length
218 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
24.095 kDa
Sequence
MFTGIIESIGNIGAIIRHNEDLSIVVNTNNLDISDVNIGDSIATNGVCLTVSKLLPSGYTADLSLETYKRTAFHSYRIGQEVNLEKAMLPTTRLGGHLVSGHVDGVGEVIEFKRNGRAINIWVAVPVQLKKYLSEKGSVTIDGISLTINAVYQNVIKLTIVPHTLAETNLVNINIDKKVNVEIDMMARYLEKLIKVDRYESEKTSNVSMDLERYGFIS

Gene
ribE
Protein
Riboflavin synthase
Organism
Photobacterium phosphoreum
Length
218 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
23.639 kDa
Sequence
MFTGIIEAVGNISAITSKGSDFEVSVNCDTLDLADVKIGDSIATNGICLTVVKLTANSYVADLSIETLSRTAFNYYKVGQAVNLEKAMLPTTRFGGHIVSGHVDAVAEVIECRTSGRAIDIWIRVPSQIEKYLSEKGSVTVDGVSLTVNAVTGNEFKLTIVPHTVVETTIADFKVGNKVNIEVDVLARYIERLLLVDKPEDKQSKISMDLLERNGFLL

Gene
ribE
Protein
Riboflavin synthase
Organism
Actinobacillus pleuropneumoniae
Length
215 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
23.404 kDa
Sequence
MFTGIIEEVGKIAQIHKQGEFAVVTINATKVLQDVHLGDTIAVNGVCLTVTSFSSNQFTADVMSETLKRTSLGELKSNSPVNLERAMAANGRFGGHIVSGHIDGTGEIAEITPAHNSTWYRIKTSPKLMRYIIEKGSITIDGISLTVVDTDDESFRVSIIPHTIKETNLGSKKIGSIVNLENDIVGKYIEQFLLKKPADEPKSNLSLDFLKQAGF

Gene
ribE
Protein
Riboflavin synthase
Organism
Bacillus amyloliquefaciens
Length
215 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
23.089 kDa
Sequence
MFTGIVEETGTIQAIKKTGLSMALTIAASKVTSDVRLGDSIAVNGICLTVTGFSDNQFTVDVMPETVKATSLNGLSKGSKVNLERAMSANGRFGGHFVSGHVDGTAEITRIEKKSNAVYYDLKLSPELTKTLVLKGSITVDGVSSTIFGLSDESVTVSVIPHTISETIFRTKAVGSIVNIECDMIGKYLYRFLHKTEQTKSNQTITEAFFSENGF

Gene
ribE
Protein
Riboflavin synthase
Organism
Bacillus subtilis (strain 168)
Length
215 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
23.481 kDa
Sequence
MFTGIIEETGTIESMKKAGHAMALTIKCSKILEDVHLGDSIAVNGICLTVTDFTKNQFTVDVMPETVKATSLNDLTKGSKVNLERAMAANGRFGGHFVSGHVDGTAEITRIEEKSNAVYYDLKMDPSLTKTLVLKGSITVDGVSLTIFGLTEDTVTISLIPHTISETIFSEKTIGSKVNIECDMIGKYMYRFLHKANENKTQQTITKAFLSENGF

Gene
ribE
Protein
Riboflavin synthase
Organism
Shigella flexneri
Length
213 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
23.445 kDa
Sequence
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA

Gene
ribE
Protein
Riboflavin synthase
Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Length
212 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
23.742 kDa
Sequence
MFTGIVRGLGKVVKILKEKKISQWEVETSNELVKNLMLGASISCNGCCLTVRNIFRTIFCVDIVEETLRSTSLNTIIVGQYINLERSIKFGEEVGGHLVSGHIITTGVVSDKKELFSNQELWISLSASFFIKYFFYKGFVCVDGISLTIGSIKNNAFCVFLIPETILRTTIGQKIIGDVVNIEIDFYTQITVDSVERLLKVHPSKFINCIDI

Gene
ribE
Protein
Riboflavin synthase
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Length
208 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
23.505 kDa
Sequence
MFTGIINGTATIVYIEKKKKKYRYTVELPSNLSKNLKLGDSISHNGCCLTVKLINNSFIICDVIQETLKSTNLGILNIGDSINIERSIKYGDEIGGHIISGHVMNTAEISKMSKSDNNCVIWLKMNNMSLMKYIFYKGFICVDGISLTVNDIIKNEFCVNIIPYTFLFTTIKDKKNGSLVNIEIDFYTQTIVDTTERLINNNLKSLYD

Gene
ribE
Protein
Riboflavin synthase
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Length
208 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
23.365 kDa
Sequence
MFTGIVNGIARVVSINKKKNFHTYTVNFSSILLKNLKIGDSVAHNGCCLTVKYINCPHVVFDIMKITIANTNLGVLNIGDYVNIERSLKYGDEMGGHIISGHIMNTGEISKISKLDKNYILWCKVKDLSLMKYIFYKGFIAIDGISLTINNIIKNEFCVSIIPETLSSTTIGFKKIGQLVNIEIDFYTQIIVDTTKRLIKKDISTLFK

Gene
ribE
Protein
Riboflavin synthase
Organism
Aquifex aeolicus (strain VF5)
Length
207 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
23.196 kDa
Sequence
MFTGLVEDLGKVKNLTLSSKGAKLSVETKLEDVKLGDSVSVNGACLTVVDIKSSTLTFDVSPETLKRTNLGKLKTGDYVNLERALRVGERLGGHIVQGHVDFTAPVKSFNFLGEHYELVIEIPEEWSIYVVEKGSIALDGISLTVNYVKENKVFINIIPHTYKSTNLQFKKVGDLLNVETDILGKYVINYLNKLKKKEDIFKEFLKW

Gene
ribE
Protein
Riboflavin synthase
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Length
204 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
22.59 kDa
Sequence
MFTGIVQGTAPIHSIKEKANFRTQVVKLLPEMRKDLEIGASIANNGVCLTVTEINGDLVSFDLMQETLKITNLGTVKVGDYVNIERAMQMGTEIGGHLLSGHIYCTAKISDIIASENNRQIWFELPSADVMKYILTKGFVAVDGISLTIGEVRDTQFCVNLIPETLQRTLMGRRKVGDIVNIEIDPQTQAIVDTVENYLQSKNF

Gene
ribE
Protein
Riboflavin synthase
Organism
Brucella abortus (strain 2308)
Length
202 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
22.223 kDa
Sequence
MFTGIITDIGKVDRVKPLNEGVLLRIETAYDPETIELGASIACSGVCLTVVALPEKGSNARWFEVEAWEEALRLTTISSWQSGRKINLERSLKLGDEMGGHLVFGHVDGQAEIVERKDEGDAVRFTLRAPEELAPFIAQKGSVALDGTSLTVNGVNANEFDVLLIRHSLEVTTWGERKAGDKVNIEIDQLARYAARLAQYQK

Gene
ribE
Protein
Riboflavin synthase
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Length
201 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
21.32 kDa
Sequence
MFTGIVEERGEVTGREALVDAARLTIRGPMVTADAGHGDSIAVNGVCLTVVDVLPDGQFTADVMAETLNRSNLGELRPGSRVNLERAAALGSRLGGHIVQGHVDATGEIVARCPSEHWEVVRIEMPASVARYVVEKGSITVDGISLTVSGLGAEQRDWFEVSLIPTTRELTTLGSAAVGTRVNLEVDVVAKYVERLMRSAG

Gene
ribE
Protein
Riboflavin synthase
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
201 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
21.32 kDa
Sequence
MFTGIVEERGEVTGREALVDAARLTIRGPMVTADAGHGDSIAVNGVCLTVVDVLPDGQFTADVMAETLNRSNLGELRPGSRVNLERAAALGSRLGGHIVQGHVDATGEIVARCPSEHWEVVRIEMPASVARYVVEKGSITVDGISLTVSGLGAEQRDWFEVSLIPTTRELTTLGSAAVGTRVNLEVDVVAKYVERLMRSAG

Gene
ribE
Protein
Riboflavin synthase
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
201 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
21.32 kDa
Sequence
MFTGIVEERGEVTGREALVDAARLTIRGPMVTADAGHGDSIAVNGVCLTVVDVLPDGQFTADVMAETLNRSNLGELRPGSRVNLERAAALGSRLGGHIVQGHVDATGEIVARCPSEHWEVVRIEMPASVARYVVEKGSITVDGISLTVSGLGAEQRDWFEVSLIPTTRELTTLGSAAVGTRVNLEVDVVAKYVERLMRSAG

Gene
ribE
Protein
Riboflavin synthase
Organism
Chlamydia pneumoniae
Length
200 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
21.701 kDa
Sequence
MFSGIIQELGEVCFFEAQGNGLSLGIKSTPLFVTPLVTGDSVAVDGVCLTLTSCNESKIFFDVIPETLACTTLGEKRCSDQVNLEAALKMGDSIGGHLLSGHVFGTAEIFLIKENRYYFRGSKELSQYLFEKGFIAIDGISLTLVSVDSDTFSVGLIPETLQRTTLGKKREGERVNIEIDMSTKIQVDTVKRILASSGKD

Gene
ribE
Protein
Riboflavin synthase
Organism
Chlamydia trachomatis (strain D/UW-3/Cx)
Length
199 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
22.222 kDa
Sequence
MFSGIIQEVARVDLIHHLRDSMEIGVFARKLIDVVPGSSFSVDGICLTLVKRQYELLFFDVTEETMAWTTIKDYTVGTMVNLERSVRLGDEIGGHFVSGHVCGIGTIIAIEKSYMFFKAPANLVPYILEKGFIAIDGISLTIARVKGDIFSVSLIPETRARTSLGYKQVGAHVNMEPDMMTKMQVDTIMRFHAEKEISK

Gene
ribE
Protein
Riboflavin synthase
Organism
Chlamydia muridarum (strain MoPn / Nigg)
Length
198 amino acids
Function
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
Mass
21.761 kDa
Sequence
MFSGIIQEVARVDLIHHYGDSMEIGIFARNLVDGVPGSSIAVDGICLTLVKREFELLFFDVTEETMACTTIKNYTVGSMVNLERSVRLGDEIGGHFVSGHVCGVGTIIAVEKSYMFFKAPTNLVPYVLEKGFIAIDGISLTIAQVRGDIFSVSVIPETRARTSLGYKQVGSHVNMEPDMMTKMQVDTVMRFQAEKIGK

Gene
ribE
Protein
6,7-dimethyl-8-ribityllumazine synthase
Organism
Escherichia coli (strain K12)
Length
156 amino acids
Function
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
Similarity
Belongs to the DMRL synthase family.
Mass
16.157 kDa
Sequence
MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA