ribD2

Gene

ribD2

Protein

2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase

Organism

Aquifex aeolicus (strain VF5)

Length

224 amino acids

Function

Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.

Similarity

Belongs to the HTP reductase family.

Mass

25.257 kDa

Sequence

MERPYVIIVSEVSVDGKLTLYRGASSKELMSLMDEEAYKYLHEIRAKVDGIMVGCETVRTDNPSLTVRYAKGKNPVRIIPCSTANVPLDANVLNTKEAPTIIATTERAPKERLEKIKELGAEVIVVGDELVDFDKLLPELYRRGIKSLMVEGGASINWEFVRRRVVDEIRLIHLPVIVGGENVPTLVGGEGFKKLKNLLHLRLRSHFVRGKQLITEWEVVNKIR

Protein

2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase: ribD2

Gene

ribD2

Protein

5-amino-6-(5-phosphoribosylamino)uracil reductase

Organism

Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)

Length

217 amino acids

Similarity

Belongs to the HTP reductase family.

Mass

25.345 kDa

Sequence

MSIDGRIAMKNGESRWITSKESREDVQKFRAKSSAILTSSATILNDDPLLNVRYKKFDKNTLSTFPKKIFQQPIRIIIDSKNRVKKSHKIIQTKEKILLMRLKLDKEIWPENTKQIIIKPYKENIDLLCVLKFLGNLEINNLWIEAGSTLSGCFLKLELIDEIIIYIAPKILGHEAKPLFIFNNQLKLFDCLKFDFKDIRQIGPDIRIKLEPKNKKF

Protein

5-amino-6-(5-phosphoribosylamino)uracil reductase: ribD2

Gene

ribD2

Protein

5-amino-6-(5-phosphoribosylamino)uracil reductase

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)

Length

207 amino acids

Similarity

Belongs to the HTP reductase family.

Mass

23.942 kDa

Sequence

MRNGDSKWITSKQARQDVQKFRAKSSVILSSSSTILSDNPLLNVRYKELDKKTLSIFPNKIFQHPIRVIIDSKNRVQPSHNIIKTKGKIWLIRLKSDRKIWPKNTTQIIEKDHNKKINIFSLLKFLGQSEINNVWIEAGSTLSGFLLNSYLIDELIIYMAPKILGHEAKPLCMIYEKLKISNSLQFKFKNICQIGPDIRLILSPKKI

Protein

5-amino-6-(5-phosphoribosylamino)uracil reductase: ribD2