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rgs7bpb

Gene
rgs7bpb
Protein
Regulator of G-protein signaling 7-binding protein B
Organism
Danio rerio
Length
251 amino acids
Function
Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cytoplasmic shuttling (By similarity).
Similarity
Belongs to the RGS7BP/RGS9BP family.
Mass
28.455 kDa
Sequence
MCSAPNGRKNRPRSAANIFQIGKSSVRDPERRESTESARRAQRAMDDCRTTVQEFNTLVALHREQVISIGENTTDCPSLRAQMHKTRVKGCAVAQAAYQNLIAISGPEDGEIHPEICRLFIQLQCCLEMYITEMLKSMCLLGVLQLHRKGNDMCPELNMDCRVDESSDVPMLEDRSSSPMDFPQDSWVVCADIENIESDMREMRNLLSKLRETMPLPLKNQDDSSLLNLTPYPLVRQRKRRFSGLCCLVSG