rgs7bpa

Regulator of G-protein signaling 7-binding protein A

248 amino acids

Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cytoplasmic shuttling (By similarity).

Belongs to the RGS7BP/RGS9BP family.

27.877 kDa

MSSAPNGRKNRPRTAGTIFQIGGKAPSRESERRESSEALLAVSDCRMVVQEFNTLVALYRELVISIGEISADCPSLRAEMHKTRTKGCEMARTAHQNLSAISGPEDGEIHPEICRLFIQLQCCLEMYLTEMLKSVCLLGSLQLHRKGKHYLGATKLDSRKEDSSDIPILEDTSSTPPDCPHTYFLVATDIENIERDMTEMKNLLSKLRETMPLPLKNQDDSSLLNLAPYPMVRQRKRRFFGLCCLVSS