rest-b

RE1-silencing transcription factor B

529 amino acids

Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells (By similarity). Plays a role in the early development of the nervous system and is required for proper patterning of the neuroectoderm during gastrulation. This involves the correct speciation of the neuroepithelial domain and adequate development of the non-neural ectoderm (By similarity).

60.019 kDa

single

MATQMVNQSTGNSLFCTSTYSNISLDNDMYGLHDLSKADMAAPRLIMLANVALTGELSSGCCDYTPEGERQMAELTTVNDNSFSDSEGDRLEDSPSMDIQSHNFIMEMEPAECSKEGTSENDGTLLSNTLEVEVQKDKRTPSPTDDKYKCVKSKPFRCKPCQYKAESEEEFVHHIKIHSAKIYVDNDSNKKAQGNEADSSISEESDVSKGPIQCDRCGYNTNRFDHYLAHLKHHNKAGENERVYKCTICTYTTVSEYHWKKHLRNHYPRILYTCSQCSYFSDRKNNYIQHIRTHTGERPYQCILCPYSSSQKTHLTRHMRTHSGEKPFKCEQCSYVASNQHEVTRHARQVHNGPKPLTCPHCDYKTADRSNFKKHVELHVNPRQFLCPVCDYAASKKCNLQYHIKSRHSGCTNITMDVSKVKLRTKKGDIGVADVDANKQTENGNIIDKSVEETVKAEKRESCGKAKKSIVNLVDGQVAKKRRLSSTQKKIKTSDARPEKILDKSRKSSCVKRKSDLLENSNDTQTSTV