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rest-b

Gene
rest-b
Protein
RE1-silencing transcription factor B
Organism
Xenopus laevis
Length
529 amino acids
Function
Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells (By similarity). Plays a role in the early development of the nervous system and is required for proper patterning of the neuroectoderm during gastrulation. This involves the correct speciation of the neuroepithelial domain and adequate development of the non-neural ectoderm (By similarity).
Mass
60.019 kDa
Fragment
single
Sequence
MATQMVNQSTGNSLFCTSTYSNISLDNDMYGLHDLSKADMAAPRLIMLANVALTGELSSGCCDYTPEGERQMAELTTVNDNSFSDSEGDRLEDSPSMDIQSHNFIMEMEPAECSKEGTSENDGTLLSNTLEVEVQKDKRTPSPTDDKYKCVKSKPFRCKPCQYKAESEEEFVHHIKIHSAKIYVDNDSNKKAQGNEADSSISEESDVSKGPIQCDRCGYNTNRFDHYLAHLKHHNKAGENERVYKCTICTYTTVSEYHWKKHLRNHYPRILYTCSQCSYFSDRKNNYIQHIRTHTGERPYQCILCPYSSSQKTHLTRHMRTHSGEKPFKCEQCSYVASNQHEVTRHARQVHNGPKPLTCPHCDYKTADRSNFKKHVELHVNPRQFLCPVCDYAASKKCNLQYHIKSRHSGCTNITMDVSKVKLRTKKGDIGVADVDANKQTENGNIIDKSVEETVKAEKRESCGKAKKSIVNLVDGQVAKKRRLSSTQKKIKTSDARPEKILDKSRKSSCVKRKSDLLENSNDTQTSTV