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res

Gene
res
Protein
Type III restriction-modification system StyLTI enzyme res
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
990 amino acids
Function
Cleaves DNA some 25 base-pairs downstream from the recognition site. May also act as a helicase involved in unwinding DNA at the cleavage site. Protein only required for restriction but needs the presence of the modification enzyme.
Similarity
Belongs to the type III restriction-modification system res protein family.
Mass
113.388 kDa
Sequence
MMNILLEELPHQEQALAAILASFTGIDHAQADHNHYANPLIKERYDDKANIDVKMETGTGKTYVYTRLMYELHQKYGLFKFVLVVPTPAIKEGARNFITSDYARQHFSQFYENTRMELCTINAGDFKVKSGRKNFPAQLLSFTDASRRDSHTIQVLLINAQMLNSASMTRDDYDQTLLGGLTSPVKGLQMTRPVVIIDEPHRFARDNKFYRAIQAIQPQMIVRFGATFPDIVEGKGKNKCVRKDYYRRQPQFDLNAVDSFNDGLVKGIDIYYPNLPEEQANNRYIVDSVTAKKLILRRGSKIAEVGVGENLADVDAGFEGSIEYAGSKMLSNDLELEAGMALVPGTFGASYQELIIQDAIDKHFDTEQANFLRSNEPENNAPRIKTLSLFFIDSIKSYRDDEGWLKVTFERLLKKKLTQLIDDYQRKTLPREVEYLSFLQATLASLHSDNQNVHAGYFGEDRGSGDEAIQAEVDDILKNKEKLLSFSDHHGNWETRRFLFSKWTLREGWDNPNVFVIAKLRSSGSESSKIQEVGRGLRLPVDENGHRVHQEEWPSRLSFLIGYDEKAFASMLVDEINRDSKVQLNEQKLDEAMITLIVTERQKVDPAFTELRLLEDLDDKKLINRSNEFKPSVTLNGETKSGFAWLLEFYPELTQARVRADRIRDNKPASRLRVRLRKENWEQLSSIWEQFSRRYMLQFERSGASLEQIAAEVLRDPALYIRQKPSQVQQRLVSNEDNGRFEVAQREGELAASEFMAGMKYGHFLKQLALRTSLPVNVLHPVLMAMLRDVLHGDSRYLSEISLDNMTRALQTRINAHFAQRHDYLPLDFQASTSVFDSTARQFREEISAEIVGKNVDENAIDDPRSLYQIPPLRYDSVDPELPLLKYDYPQQVSVFGKLPKRAIQIPKYTGGSTTPDFVYRIERQDADSVYLLVETKAENMRVGDQVILDAQRKFFDMLRRQNINVEFAEATSAPAVFSTINGLIEGKAN

Gene
res
Protein
Type III restriction-modification system Bce10987IP enzyme res
Organism
Bacillus cereus (strain ATCC 10987 / NRS 248)
Length
987 amino acids
Function
This protein cuts the DNA outside of the recognition site. May also act as a helicase involved in unwinding DNA at the cleavage site. Protein only required for restriction but needs the presence of the modification enzyme (By similarity).
Similarity
Belongs to the type III restriction-modification system res protein family.
Mass
114.787 kDa
Sequence
MKILLEELPHQEESLKAILENFTGIDNAANDSDVDYVYANPLIRGRYNEISNIDVKMETGTGKTYVYTRLMYEMHQQYGIFKFVIVVPSPAIKEGAKNFIQSDYAKQHFSQFYENVRIELNVINAGDFKSKSGRRNFPAQLLNFVEGSRQNSNTIEVLLINADMLRSKSMRNNDYDQTLIGGTTSPIEAIQDTRPVVIIDEPHRFPRDKANYQSIEAIKPQVIIRFGATFPEVTTGKGSNKITKKDYYRKKPQFDLNAIESFNNGLVKGIDIYYPNLTEEQAKNRYVVDSVKAKELVLKQNSKSWILHVGDNLAEVDSGFEGDIEYAGSKMLSNELELEKGMTLIPGTYRSTYQELIIKDAIDKHFEIEQANFLRANQRENNVPRIKTLSLFFIDSITSYRQDDGWLKATFERLLKEKLSRLVAEYEFKRLPREKEYLEFLRATQSSLASDNQNVHAGYFGEDRGSGDESIQAEVDDILKNKEKLLSFKDENGNWQTRRFLFSKWTLREGWDNPNVFVIAKLRTSGSDNSKIQEVGRGLRLPVDETGHRIQQDEWPTRLAFLIGYDEKDFAQKLIGEINSDAKLQLNEEKLTEDMIQLIVTKRKKVNPEFTDERLLEHLDNLGIINRKNEFKESIDIGGVQKSGFEWLVELYPELNTNRLREGKVIDTKKHSIKVRVKLRKENWEKVKELWQQFSNRYMLEFQRIPETISFMAEQIVGNHSLYEREVPMQMKESLHASDDNESVVLREQENEYQRIYLPGMAYGKFVKRINIATGIPIKEIHANLFKLMKSSLKGDARYLSELSLNNIIREFKKRFDEIFAQAYEYKKLDFQARTAIYNPEMDSFVDDINAEVIGVNIDEQAQEDNRYLYELPPMRYDSVTPERDLLRHGYNDKVTVFGKLPRRAIQVPKYTGGSTTPDFIYMIEKDNDSSVYVLVETKAENMRLEDQRIIDIQKKFFDTLKEHHIEFIEATSAQQVYSIIRKLSEE

Gene
res
Protein
Type III restriction-modification system EcoPI enzyme res
Organism
Escherichia phage P1
Length
970 amino acids
Function
This protein cuts the DNA some 25 base-pairs to the 3'-end of the recognition site. It is only required for restriction but needs the presence of the modification enzyme.
Similarity
Belongs to the type III restriction-modification system res protein family.
Mass
111.459 kDa
Sequence
MSKGFTFEKNLPHQKAGVDAVMNVFVSATSHQEDNVSIRLLVNPELRLTEQQYYKNIKKVQELNGIEHVKNNYDARSNVIDVSMETGTGKTYTYTKTIFDLNKSFGINKFIIIVPTLSIKAGTVNFLKSDALKEHFRDDYEREIKTYVVESQKNAGKSTKSYMPQAIHDFVEASNFNKKYIHVLVINTGMIHSKNLNSTYDVGLLDNHFDSPFSALGAVKPFIIIDEPHKFPTGKKTWENIEKFNAQYIIRYGATFSEGYKNLVYRLTAVDAFNEDLVKGIDAYIEDIVGDGDANLKFIKSDGEEVTFELNENNKKTLFKLTKGESLSKTHSAIHDLTLDALGKNTVVLSNGIELKIGCSINPYSYDQTLADSMMRKAIKEHFKLEKEFLTQRPRIKPLTLFFIDDIEGYRDGNNIAGSLKAKFEEYVLAEANELLKIEKDEFYSNYLEKTVKDISSVHGGYFSKDNSDKDDKIEKEINEILHDKELLLSLDNPRRFIFSKWTLREGWDNPNVFQICKLRSSGSTTSKLQEVGRGLRLPVNEYMCRVKDRNFTLKYYVDFTEKDFVDSLVKEVNESSFKERVPSKFTQELKEQIRAQYPELSSRALMNELFNDEIIDDNDNFKDSDAYSRLKSKYPAAFPIGVKPGKIKKATDGKRRTKMRVGKFSELKELWELINQKAVIEYKINSENEFLSIFKSFMLEETERFTKSGVHTRIDKIYIHNDMAMSKSIVSDDDDFAKLNTMSYREFLDNLSQTIFVKHDTLHKVFCDIKDTINITEYLNIQTIRKIKSGFSKYLLNNSFNKFSLGYNLISGSIHPTKFTNADGKPLDEVLSSDLGVLQDNSKAPLDTYLFEEVFYDSELERRNITDREIQSVVVFSKIPKNSIKIPVAGGYTYSPDFAYVVKTAEGDYLNFIIETKNVDSKDSLRLEEKKKIEHAQALFNQISQSVKVEFKTQFANDDIYQLIKSALP

Gene
res
Protein
Resolvase
Organism
Clostridium perfringens (strain 13 / Type A)
Length
189 amino acids
Function
A likely role for the res protein would be to stabilize pCP13 by reducing the number of plasmid multimers resulting from homologous recombination.
Similarity
Belongs to the site-specific recombinase resolvase family.
Mass
21.54 kDa
Sequence
MLVGYARVSTEGQSLNRQIDMLVDYGLDKRNIYQEKISGTKLRRDQLDKMIEELQEGDTVIITDLTRISRSTKDLLNIIDRIKEKGASIKSLKDTWLDTSGDNPYNSFLLTVMSGLSQLERDLISQRTKEGLRSAKARGRNGGRPSKRNDKADTVGLLYREGYKIVDIVKQTELSRATVYRILKDLNLK

Gene
res
Protein
Resolvase
Organism
Clostridium perfringens
Length
189 amino acids
Function
A likely role for the res protein would be to stabilize pIP404 by reducing the number of plasmid multimers resulting from homologous recombination.
Similarity
Belongs to the site-specific recombinase resolvase family.
Mass
21.428 kDa
Sequence
MLVGYARVSTEEQSLNRQIDMLVDYGVDKRNIYQEKISGMKPNREQLDKMIDELQEGDTVIITDLTRISRSTKDLLNIIDRIKAKGASIKSIKDTWLDTSSDNPYNSFLLTVMSGLSQLERDLISQRTKEGLKSAKARGRNGGRPSKRNDKADTVGLLYREGYKIVDIVKQTGLSRATVYRVLNDLKLK