Protein
Replication initiation protein
Organism
Staphylococcus aureus
Function
This protein is probably a specific topoisomerase involved in initiating replication. This protein is specifically required and may be rate-limiting for replication of the plasmid in vivo.
Similarity
Belongs to the plasmid replication initiation factor family.
Sequence
MSKNNYTNHSNHLENHDSDNFSKTGYSNSRLDAHFVCTSNPKLSFDAMTIVGNLNKNSAKKLSDFMSLDPQIRLWDILQTKFKAKALQEKVYIEYDKVKADTWDRRNMRVEFNPNKLTHDEMLWLKHNIIDYMEDDGFTRLDLAFDFEDDLSDYYALSEKALKRTVFFGTTGKAETKYFGSRDSNRFIRIYNKKKERKENADVDVSAEHLWRVEIELKRDMVDYWNNCFNDLHILKPAWATLESLKEQAMVYLLLHEESKWGELHRNSRRKYKQIIQEISSIDLTDLMKSTLTDNEENLQKQINFWQRKFEFWK