Protein
RepFIB replication protein A
Organism
Escherichia coli (strain K12)
Function
This protein is essential for plasmid replication; it is involved in copy control functions. In vitro, binds to the DNA repeat units, BCDD'D'', EFG and HIJ.
Similarity
Belongs to the initiator RepB protein family.
Sequence
MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNTLSRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVELPFVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSAYYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPAPISLARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKFFCIHYRRPRLKAPNDESKENPLPPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR