rei-2

Gene

rei-2

Protein

Guanine nucleotide exchange factor rei-2

Organism

Caenorhabditis elegans

Length

431 amino acids

Function

Guanine nucleotide exchange factor for Rab GTPase Rab-11.1 (By similarity). May spatially and temporally regulate the distribution of Rab-11.1 to target membranes during embryogenesis (PubMed:26506309). May play a role in cytokinesis, probably by targeting rab-11.1 to the cleavage furrows (PubMed:26506309).

Similarity

Belongs to the SH3BP5 family.

Mass

48.935 kDa

Sequence

MDETATSSEVTETFVSDPTTRQFEEDGHPPLETRHLNMIHEELEKLNISTDVINKMEVQLDLARADFRETQVQWSEKLKELSKQYSSQIAKARPFYELKIKERSLREESQKAAERFERATSILGIAKQQVSLTQESLSRQTSVLPECLEVLNHHIQRVREVEEERTAAESLHASKAHAMLHLAEKIRAMEKDNRYAIKKSRLYFEKRLEFTKILEAQKATILCLEAEVRQKKNDYTTSLRNLERISERIHEERSTGSLESAVSSDQEDQKSDFKSSESLPGNPPPYAPTAPPPYEDKYIIDKDDDSIVLNMIKTEQEEEGEKRNSRSLGSGVILLAQQLIGNGNSTEKHNITPPRHGEEADISYHTRPVGLSDGSDNSEVSSLASFNIGDDDTVSKMLMSHSELIKDIELATDRVGHILKPNIKSVSNAHE

Protein

Guanine nucleotide exchange factor rei-2: rei-2