Protein
Guanine nucleotide exchange factor rei-1
Organism
Caenorhabditis elegans
Function
Guanine nucleotide exchange factor for Rab GTPase Rab-11.1. Spatially and temporally regulates the distribution of Rab-11.1 to target membranes during embryogenesis. Plays a role in cytokinesis, probably by targeting rab-11.1 to the cleavage furrows.
Similarity
Belongs to the SH3BP5 family.
Sequence
MTEGDDQLISIRKQLENLNNATDDINSYEMKLETVKKQFCETQLMFNKEMLGIPKKLAKHISKSRQFFDLKSRESEIRRCVQQAAAQFERQKTSVEMAREQVQILHNSLNNNQELDAEKQYVDVIEQQLELVKEAEGECLKAEKCHASRVRDLLQLEMALRKCLEENGSAIKKSRPYYERKEVLTRTMNSQLELMSILEHEVQERKDSYSDSMRALEQISDQIHQERSSQSSLAPSSDAESDSS