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ref(2)P

Gene
ref(2)P
Protein
Protein ref(2)P
Organism
Drosophila melanogaster
Length
599 amino acids
Function
Required for selective autophagy activation by ubiquitinated proteins (PubMed:22622177). Implicated in sigma rhabdovirus multiplication and necessary for male fertility. Involved in activating transcription of Drs (PubMed:12446795, PubMed:2510997).
Mass
65.303 kDa
Sequence
MPEKLLKITYQGAGPQKKINAYLRMPSQNYTILRREIELYLFQERQLPKCDVRTFWIDADKDEIEIVNQNDYEIFLAKCESNMHVQVAPLAPVEEPKATKQEGSSANAEAPSVDDPSNFTIHDAVECDGCGLAPLIGFRYKCVQCSNYDLCQKCELAHKHPEHLMLRMPTNNGPGMVDAWFTGPGLGRRSGRRSRGHCPFQETNQADPAGEPARDSRRERRQARRHAGVLTQFVEMMTNLPLNTTTATAPAEPQKPKAAEQTESPPQAEPTVTAEKAAESEAKPTEPKKVNTDQSVPRTEDPVTTPRSTQPTTPVINLDNISQIVPPEYMSAGIEILNNFSEMFSKIIDTTEGGDSGIFAPSTTPSAENKKPEEQGQSSGQSGASSANQSAVPSAAPSANQSNVPSANQSATPSISGSIPDAQLETEPLNPKPSETTTETEQERRRSDSLDPEWQLIDNAYSANNSNLINLDTTNPTAAPQEPVRDFGQLGELLRQHMNEEARVEQASANTQTAQVDTVSTSTSTTSVTTNSVGTSPAAPDDKRTVPVYHTDESINKSIHAMMAMGFSNEGAWLTQLLESVQGNISAALDVMNVSQNRN

Gene
ref(2)P
Protein
Protein ref(2)P
Organism
Drosophila simulans
Length
599 amino acids
Function
Required for selective autophagy activation by ubiquitinated proteins. Implicated in sigma rhabdovirus multiplication and necessary for male fertility. Involved in activating transcription of Drs.
Mass
65.431 kDa
Sequence
MPEKLLKITYQGAGPQKKINAYLRMPSQNYTILRREIELYLFQERQLPKCDVRTFWIDADQDEIEIVNQNDYEIFLAKCESNMHVQVAPLAPIEEPKATKQEGSSANAEAPSVDDPSNFTIHDSVQCDGCGLAPLIGFRYKCVQCSNFDLCQKCESAHKHPEHLMLRMPTNNGPGMVDAWFTGPGLGRRCGRRSRGHCPFQEASQPAPAAEPARDSRRERRHARRHAGVLSQFVEMMTNLPLNTTTATAPAEPQKPKAAEQTESPPQAEPTVTAEKATESEAKPTEPMKVNTDQSVPTTEDPVTTPRSTEPTTPVINLDNLSQIVPPEYMRAGIEILNNFSEMFSKMIDTTDVGDSGIFAPSTTSSAENKKPEEQSQSSGQSAASSASQSAVPSAAPSANQSNVPSANQSATPSISGSISDAQLETEPLNPKPLETTTETEQDRRRSDSLDPEWQLIDNAYSANNSNLINLDTTNPTAAPQQPVRDFGQLGELLRQHMNEEARVEQASANTQTAQVDTVSTSTSTTSVTTNSVGTSPAAPDDKRTVPVYHTDERINQSIHAMMAMGFSNEGAWLTQLLESVQGNIPAALDVMHVSQTRN