Protein
Retinol dehydrogenase 10-A
Function
Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Sequence
MHIVLEFFLVTFRVLWAFVLAAGKWLLRPKDKSVAGQVCLITGAGSGLGRLFALEFARRRAQLVLWDINSQSNEETAEMVRNIYRELEAEDSARRANSSAEEEVLPCCNLKVYTYTCDVGKRESVYSTAERVRREVGDVYLLLNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPKMMELNHGHIVSVASSLGLFSTAGVEDYCASKFGVVGFHESLSHEIKASDKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMRAILTDQPMICTPRLMYIVTCMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI