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rde-10

Gene
rde-10
Protein
RNA interference defective protein 10
Organism
Caenorhabditis elegans
Length
627 amino acids
Function
In complex with rde-11, required in the endogenous and exogenous siRNA pathway for biogenesis and accumulation of secondary small interfering RNA (siRNA) intermediates, such as 22G-siRNAs derived from ergo-1 targets.
Similarity
Belongs to the maelstrom family.
Mass
72.155 kDa
Sequence
MSNHRSNFRDYQREGIRANNAGTSGDAVRQNGNPISVAKHVDGKKSVYMLFLRQIGQKKFLTEQGHRYNQNDQADKDIMTRYYHGMCPDLKQKFEREVAEHNGNRGLVIKTKHQRAQRNREMRHRNPDEFQQLRRAHLETLSQTPSVIALPRDINHVLHITEDLDAFCLANRKKAKRIMTSYIAQRSDDPGNPLLCEDYTMQIVSVFPVAYAFKPSINKLSSYPAEISVTTFNLKNGIIQNESRFVKFDAAWFYPDADDIGHEELSRKAMADELGISPNGPADGCEPYEVFEWLQHLLKQHPKSPILCDRAQFNFVYYGIKTLATYTGINAITFFQEVIIPSILSIQDFTSVILEKAPTDVPRVWRDVDICNQFQYHFLIPRTELNLFCSFHENKPSPTKYNCVKAHNARLLDNFFTVIKGNRLQGFVISPPVHEICIQDGSDTSLPQTILARTISRNDAEVYAARQRDTDEQYDVHQEGPSNHDQYEFASEPLDFEEDSDEENYNEQLDVPYSYNDHFISSSSVREPEHPSARSRDVAPNVQQESVVVPAPRRLSPQRAPRPSQNSPNAYSERKSFSAFPSEDPSEDYETPIISHIMNRNEADQYFNILDSVKPGQKYKIIKFDDF