rasgrp2-a

Gene

rasgrp2-a

Protein

RAS guanyl-releasing protein 2-A

Organism

Xenopus laevis

Length

594 amino acids

Function

Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May function in cell aggregation and adhesion.

Similarity

Belongs to the RASGRP family.

Mass

68.118 kDa

Sequence

MDSSDLDKGLTIDDIVVKCIQSFDKDGKLSDPEFVQMFLMMHPWYIPSGDLAKKLSALSESGDNVERERICQLVRFWISEFPAEFDLNPELGEQIRDLKRALENKGNRRESNLIDIESVPSYGWKRQVTQRGPSGGRVRKTSLLFDHLDPAELAEHLTHLEFHSFSKILFQDYHSFVLHGCTVGNPVLERFIALFNGVSQWIQLMVLSKHTPQQRAAVIKQFVQVAEKLLQLQNFNTLMSVVGGLSHSSISRLKDTQSHISPETTKVFDSLLELLTSSDNYARYRRRFATCEGFHFPALGVHLKDLMALHVALPDWADKAKTIINISKMRQVYKVVHELTEAQRLEPPVKANPDLLNLLTVSLDQYRSEEEIYQLSLQREPRARTTQTNAKSPPSPSPPLEEWASLKAKPDQALLCQHIEKMVESVFRLFDEDGDGHISQEEFQSVRSNFPYLCAFNEIDQNHDGKISKQEMTSYFQRASSVLDCKMGFIHNFAERTFLRPVSCQHCGNLILGIYKKGLKCRACGITCHKHCKDHLSIECKKRSKSVSERGESMEKGRHFSFTLPRSFRRSTLYPDLREEEPQLEEDGVFDDRL

Protein

RAS guanyl-releasing protein 2-A: rasgrp2-a