ramA

ABC transporter ATP-binding protein RamA

636 amino acids

Probably involved in exporting SapB from the cell (Probable). Expression of the ram locus (ramA, ramB and ramR) induces rapid aerial mycelium formation in S.lividans (PubMed:8206859).

Belongs to the ABC transporter superfamily.

65.481 kDa

MSPAAGAPGSGPGRRRLPALDVRRFSPVRKSRPVPPRAPGRALEVLVLLCSVAAAVAAVAQPLALGRTLDLLLRDGDAGWWLPLSAALLLGELLLDSATSLFTGRCNATWTASVRTRALRGLLRTAPEHARPYPPGDIGTRLTLNAADAGGAPAARAALAASLITPLGALVALALVDVWVALCVLTGLPALALLLRSFARDTGATVAAYQRTQSLIASRLLEALEGADTIGAAGTGERERARVLAPLAELAAQGRHMWALHGRALGRSGVLVPLLTLAATAVGGLRLAAGELSVGDLLAVGRYAQLTAGVGAAASLLGAIVRAREARRRTRELERMTATVYGTRRLPPNGPGELRLCGVRVLRGGREVLRADGVRVPGGSTVAVVGRSGAGKSVLAAVAGRLIDPDEGYVLLDGVRLDRLTHEALRTEVAYAFERPVLGEGTIAEAVADGARRSSRERVRQAARAAGADGFVRRLPHGYDTPLPRAPLSGGEHQRLGLARAFAHAGRLLVLDDATSSLDTATEHEVDLALRRSVRPGTRLVVAHRPSVADRADLVLWLEDGQVRAVGTHRELWHTAGYREVFGAGAGAGAGAGAGAGADAGAGADAGPGPDSGAATAVGGSGPGPVRRPEPEEARP

ramA

HTH-type transcriptional activator RamA

281 amino acids

RamA is a master regulator of acetate metabolism. It positively controls the expression of acnA, aceA, aceB, ack, pta and ramB genes in the presence of acetate (PubMed:16547043, PubMed:17114251, PubMed:19095019). RamA is also a positive regulator of rpf2 gene expression during growth on glucose as the sole carbon source (PubMed:18355281).

30.84 kDa

MDTQRIKDDEDAIRSALTSLKTATGIPVTMFATVLQDNRLQITQWVGLRTPALQNLVIEPGVGVGGRVVATRRPVGVSDYTRANVISHEKDSAIQDEGLHSIVAVPVIVHREIRGVLYVGVHSAVRLGDTVIEEVTMTARTLEQNLAINSALRRNGVPDGRGSLKANRVMNGAEWEQVRSTHSKLRMLANRVTDEDLRRDLEELCDQMVTPVRIKQTTKLSARELDVLACVALGHTNVEAAEEMGIGAETVKSYLRSVMRKLGAHTRYEAVNAARRIGALP

ramA

(R)-stereoselective amidase

274 amino acids

Hydrolyzes (R)-piperazine-2-carboxamide and (R)-piperazine-2-tert-butylcarboxamide with strict R-stereoselectivity. Also active towards beta-alaninamide, piperidine-3-carboxmide, D-glutaminamide and slightly active towards L-glutaminamide and piperidine-4-carboxamide.

30.128 kDa

MKIELVQLAGRDGDTAYNLSRTLNAIATCAGDTDLLVFPETYLSGFVGGAQLAQVAEPLHGTTLQTLLQAVRQRDVAVVLGFAEVHQGRFYNSSVLVTPEGIALQYRKTHLWPSERSDFSPGDRFTTVLWRGVRVGLLICYDIELPETSRALAQLGAEVVIVTNGNMDPYGPVHRTAIMARAQENQLFAVMVNRVGAGDDGLVFAGGSMAVDPFGRVLFEAGRDEVRHVVELDLDQLKAARRDYDYLKDRRLMLSGEQTEHPDGRRELLIGASQ

ramA

Transcriptional activator RamA

113 amino acids

Probable transcriptional activator.

13.633 kDa

MTISAQVIDTIVEWIDDNLHQPLRIEDIARHAGYSKWHLQRLFLQYKGESLGRYIRERKLLLAARDLRESDERVYEICLRYGFESQQTFTRIFTRTFHQPPGAYRKENHSRTH

ramA

Transcriptional activator RamA

113 amino acids

Probable transcriptional activator. Confers a multidrug resistance phenotype in E.coli.

13.495 kDa

MTISAQVIDTIVEWIDDNLHQPLRIDDIARHAGYSKWHLQRLFLQYKGESLGRYIRERKLLLAARDLRDTDQRVYDICLKYGFDSQQTFTRVFTRTFNQPPGAYRKENHSRAH