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ralR

Gene
ralR
Protein
Endodeoxyribonuclease toxin RalR
Organism
Escherichia coli (strain K12)
Length
64 amino acids
Function
Toxic component of a type I toxin-antitoxin (TA) system. Upon overexpression inhibits growth and reduces colony-forming units in both the presence and absence of the Rac prophage, cells become filamentous. Has deoxyribonuclease activity (probably endonucleolytic), does not digest RNA. Its toxic effects are neutralized by sRNA antitoxin RalA, which is encoded in trans on the opposite DNA strand (PubMed:24748661). Has RAL-like activity (PubMed:7476171).
Mass
7.019 kDa
Sequence
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV