rad9

Gene

rad9

Protein

Protein rad9

Organism

Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003)

Length

2072 amino acids

Function

Plays a structural role in chromatin. Involved in sister chromatid cohesion during meiosis, possibly by interacting with the cohesin complex. Also participates in DNA repair and meiotic homolog pairing.

Similarity

Belongs to the SCC2/Nipped-B family.

Mass

229.232 kDa

Sequence

MDHNSNHHWYSQNRPRNDPRIPSQQSPNTNINHHGFTNAANQTVQHAQQMLAGFPMASATPALQPVRHIANMTMTAAPPSFVQPNYYSSQAQPDYTHVQQHNSQHIPPPPYTEYDQHLSYLSAPQVPQNRTEHWHTARDQSVRLLNEQASRSYPYQEPQQPSNWPASSYQSTPFAQSVFQRTTPNSAYPTPPPPGISTSSSSLAFALGGPPQPPPRQQTVTQPLFHPTQAPLPQPAPAPQPAPVPQATVFPPPSNPPAAQASQPTYNADDSASFFNSFLERKTREMNATMQQTTSAKSIFPPAPAKLPLPVPVASKPPARMKTPPPREQKAVPDSSPDPLSLSSNMALPSSTPLKRKCVVEIHSPPPKRIQSYKPMTLISQPLTPSRGPPLTPTSRASNASSVPTTASSSTSITSMSSSSKTTVPMTPTPQRIGRKYEDTPDLGGYGSSEDTPLRRGLMSSVKRTGERDDRGPLEKFVTVVDEIFESEDSLPADLGHEDLPQEFFSSWSPDCSKPLLNTSTIRKLLKYVGQVARPTKRMRQASAGGQGLLATPRTRAGRMADVDIQTLSRLLKMLERSLKEGEEVDPFKATGSSSGLNGTVSARSSPVKKGSRKKKAKDSLDDDDSMEADEADELPQQHLKKGSTPPPNDIELEKLTRLLDLARDSVLAADCCIAILASDRLPKQLYSEELITSCLNTVKNQLTKVLYPFIEGASPDSINSKLYNGALLQHLIKNAPADPNTSANSSISQAYHRKQMSEIFQSLSSVLPRINALANAESVAMSDSIIIQTVYIAIGPFFVVEGAEESTAKSASKKEKESVVNRTLGKSAMRGLRLDALSLIRSIFSNHEDQRSWIIEEILTSLIKLSDTKQKAGQFRLRDGRSIRTVSALLMQLVQTSAHDVRINARRLEKERQNALALKRQESISDLNGQPKSDEPFLDNIDMEEIRLYGGGLESATKAAKTIIFFLNSRAGKGKTTKNSNEAEYRAIFDNLIDDLLVVLYWPEWPAASLLLNIASKFMVSSLDDVKSNAQIDTNAAKSMALDHLGVIAARIRSSILKVQKDEDGTSYRGLKPLDEIVNNLQSKQFAKFMDAHRDVAAHLCKRSTEDQAYESARELTAAILGHELAASLKRVNVWLDHPEQDEDLDLRDSSKALSFGQKLKTALREVWKDPATDVFDIGSQEEVSRIDRLSEEIGTIQSLRNSFQPILNVILSALDAPVIFMRTKALRALGQIVTSDATILGTASVRQGIENHLLDSSPAVRDAAVELIGKYMIDSPEVAGNYYQKIAERMADTGLAVRKRVIKLLKSYYGVIDDTQRKIDISARLVLRMVDEDDGVKDLAMKTLEELWFPPLPPPSAMKVKPTSSSNPNQDKAALLSKVAIIMGTAANFRDRQSPLEDMLHKIISDKEGNEAASLHQRYAEICETLIDGLVDATDLPGFTIINCIRTIHLFTAAYPSILPGTHASTLLPYLKNASTTEELLTSDFLLKIFRASIPHMPKTAAKFGQELQTSLQPLILKPFGGVNILQEAVGCMCAVVRHLTHDFKRLINLLKGCNARLLSYLRHPPTKQLNNVESKTLLMLLFIVALLGEHCNFDRLRLEQPDLAPDIDSITQGSVMEHIYFTLLRIYDKFDFADIRPRILQCLGFLFRAQPTLMTKEESAAIMDAIFASEEEEGRARLLKIMQDFLISESEKHSAKEKESAKNKNKANTDVNMEELVGNTDGFADSGVSSAIVQRYLSHILDAALSQNSQIQMAAIDVLTFTIKQGLAHPLQSFPVIIALETSPHAVLSARAIALHSILNSKHASLLNTRYSISARKSFDYQKKIVDGVVHGFRTNGHPTALLQRWYTLVREKRATRQDFLKSLVKVFSENDSYQATQDDVDFTRYMAENFASFEYKTQEEVFTVIKHLTTVLSTTGMQLLDIISPAHLLSQIQPSHSQPSQHNGGDEISSNAAEAVVPLATPNYGDRDPVSLMRTSVIVAMVMLLKSYLKTLYGLSEDKCNKFVIGKKSAIGDRPATKRSDKPISWEKLPYAVQAIHTTQDVELQKQRFLEIWNEDGVTAEPEDDEFL

Gene

RAD9

Protein

DNA repair protein RAD9

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

1309 amino acids

Function

Essential for cell cycle arrest at the G2 stage following DNA damage by X-irradiation or inactivation of DNA ligase.

Mass

148.398 kDa

Sequence

MSGQLVQWKSSPDRVTQSAIKEALHSPLADGDMNEMNVPVDPLENKVNSTNIIEGSPKANPNPVKFMNTSEIFQKSLGLLDESPRHDDELNIEVGDNDRPNANILHNERTPDLDRIANFFKSNRTPGKENLLTKYQSSDLEDTPLMLRKKMTFQTPTDPLEQKTFKKLKSDTGFCYYGEQNDGEENASLEVTEADATFVQMAERSADNYDCALEGIVTPKRYKDELSKSGGMQDERVQKTQIMISAESPNSISSYDKNKITGNGRTTRNVNKVFNNNEDNIGAIEEKNPVKKKSENYSSDDLRERNNQIIQSNESEEINELEKNLNVSGRENDVNNLDIDINSAVSGTPSRNNAEEEMYSSESVNNREPSKKWIFRYSKDKTENNSNRSTQIVNNPRTQEMPLDSISIDTQPLSKSFNTETNNELETQIIVSSLSQGISAQKGPVFHSTGQTEEIKTQIINSPEQNALNATFETPVTLSRINFEPILEVPETSSPSKNTMSKPSNSSPIPKEKDTFNIHEREVETNNVFSNDIQNSSNAATRDDIIIAGSSDFNEQKEITDRIYLQLSGKQISDSGSDETERMSPNELDTKKESTIMSEVELTQELPEVEEQQDLQTSPKKLVVEEETLMEIKKSKGNSLQLHDDNKECNSDKQDGTESLDVALIEHESKGQSSELQKNLMQLFPSESQEIIQNRRTIKRRQKDTIEIGEEEENRSTKTSPTKHLKRNSDLDAASIKREPSCSITIQTGETGSGKDSKEQSYVFPEGIRTADNSFLSKDDIIFGNAVWCQYTWNYKFYPGILLEVDTNQDGCWIYFETGRSLTKDEDIYYLDIRIGDAVTFDGNEYVVVGLECRSHDLNIIRCIRGYDTVHLKKKNASGLLGKRTLIKALSSISLDLSEWAKRAKIILEDNEKNKGDAYRYLRHPIRGRKSMTNVLSPKKHTDDEKDINTHTEVYNNEIESSSEKKEIVKKDSRDALAEHAGAPSLLFSSGEIRTGNVFDKCIFVLTSLFENREELRQTIESQGGTVIESGFSTLFNFTHPLAKSLVNKGNTDNIRELALKLAWKPHSLFADCRFACLITKRHLRSLKYLETLALGWPTLHWKFISACIEKKRIVPHLIYQYLLPSGESFRLSLDSPSKGGIIKSNNIFSFYTQFLRGSNLRDQICGVKKMLNDYIVIVWGRSELDSFVKFAFACLSAGRMLTIDLPNIDVDDTEPLLNALDSLVPRIGSELSNRKLKFLIYANENNGKSQMKLLERLRSQISLKFKKFNYIFHTESKEWLIQTIINEDTGFHDDITDNDIYNTISEVR

Protein

DNA repair protein RAD9: RAD9

Gene

rad9

Protein

DNA repair protein rad9

Organism

Schizosaccharomyces octosporus

Length

432 amino acids

Function

Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.

Similarity

Belongs to the rad9 family.

Mass

48.24 kDa

Sequence

MEFVVSNTNLRDLSRIFLNLSRIDDAVNWEINKDQLILTTLNSSRSGFGKVTLTKKFFDKFTFHPDTLFLTGFVSPTVRLSTQIKPILSIFRNKIFESTLLVNNNLNTNAGAAESSSKKNVVVENIQMQITSGKECRVIFKFNCKHGVVKTYKIAYEQTQTLHAVFDKASCHNNWQINSKILKDLIEHFGQKTEELTIQPVQGRVLLTSFTEEVVHNKDVLKQPTQTTVSIDGKEFEQVSLNEGIIITLSLKEFRAAVLLAESLGTSIASYYSVSGKPALFTFNKGKFMEIEAQFILATVMGPDDFDESSLGARWQQSGTANSSLLVPENTSAAPALENEAPSASIGWQTNGDAETSRMFHSTLDIPRNEEPAAKPSRQTTDEENHPLFLEGMPDETELMAFDNDVADDAEFGPTQHEQTYHGIFSQDDTET

Protein

DNA repair protein rad9: rad9

Gene

rad9

Protein

DNA repair protein rad9

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

426 amino acids

Function

Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. Repressor of entry into mitosis that is activated by chromosome breaks.

Similarity

Belongs to the rad9 family.

Mass

47.494 kDa

Sequence

MEFTVSNVNLRDLARIFTNLSRIDDAVNWEINKNQIEITCLNSSRSGFSMVTLKKAFFDKYIFQPDSVLLTGLMTPTIRIRTQVKPILSVFRNKIFDFIPTVVTTNSKNGYGSESASRKDVIVENVQISISTGSECRIIFKFLCKHGVIKTYKISYEQTQTLHAVFDKSLSHNNFQINSKILKDLTEHFGQRTEELTIQPLQERVLLTSFTEEVVHNRDILKQPTQTTVSIDGKEFERVALNEGVSVTLSLREFRAAVILAEALGSSICAYYGVPGKPILLTFAKGKNSEIEAQFILATVVGSDEQEVSSMMGNRWQHSSTPASLFNSVERNNSLTAVAHNPPGSIGWQTDQSDSSRMFNSALDRSDETNGIKEPSTTNDAGQSLFLDGIPNESELAAFNNDVNDDAEFGPTQAEQSYHGIFSQED

Protein

DNA repair protein rad9: rad9