About Products Protein Database Contact

rab6

Gene
rab6
Protein
Ras-related protein Rab-6
Organism
Dictyostelium discoideum
Length
208 amino acids
Function
Protein transport. Probably involved in vesicular traffic (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.387 kDa
Sequence
MESLSKYKLVFLGDQSVGKTSIITRFMYDTFDITYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAIVVYDITNKVSFTNTIKWIEDVRNERGNNVVIMLVGNKTDLADKRQVSIEEGEAKAKEYDIMFTETSAKAGFNIKALFRKVASALPGIDSNSMTKNQHEIISEVDITDGGKPALKEGDGFCSSSRC

Gene
Rab6
Protein
Ras-related protein Rab6
Organism
Drosophila melanogaster
Length
208 amino acids
Function
Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Mediates membrane trafficking during egg chamber growth and organization, possibly upstream of exocyst component Sec5. Also during oogenesis, plays a role, together with BicD but independently of Sec5, in the polarization of the oocyte microtubule cytoskeleton, in the localization of oskar mRNA and in the anterodorsal secretion of grk. Required for anterograde opsin transport through the ER-Golgi complex. Plays a role, together with Rich, in regulating CadN transport in photoreceptor cells which is required for the formation of normal synaptic connections between axons from the inner photoreceptor cells in the eye and postsynaptic cells in the brain medulla layer M6. Necessary for proper development of bristle shafts of macrochaete and microchaete on the head, thorax and scutellum. Modulates Notch signaling. As a key regulator of vesicular traffic, plays a critical role in the regulation of actin organization and is required for normal rates of phagocytic uptake during phagocytosis involved in defense against viral and fungal infection.
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
23.48 kDa
Sequence
MSSGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNTNSFHQTSKWIDDVRTERGSDVIIMLVGNKTDLSDKRQVSTEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMDSTENKPSEDMQEVVLKDSPNETKDPEGGCAC