Protein
Riboflavin biosynthesis protein PYRR, chloroplastic
Organism
Arabidopsis thaliana
Function
Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products. Thus, can divert a surplus of harmful intermediates into relatively harmless products and pre-empt the damage these intermediates would otherwise do. Helps maintain flavin levels. Has no activity against GTP, nucleoside monophosphates or ADP-ribose.
Similarity
In the C-terminal section; belongs to the YbiA family.
Sequence
MALSFRISSSSPLICRATLSNGDNSRNYHTTDAAFIRRAADLSEMSAGLTSPHPNFGCVIATSSGKVAGEGYLYAQGTKPAEALAVEAAGEFSRGATAYLNMEPGDCHGDHTAVSALVQAGIERVVVGIRHPLQHLRGSAIRELRSHGIEVNVLGEDFESKVLEDARKSCLLVNAPLIHRACSRVPFSVLKYAMTLDGKIAASSGHAAWISSKLSRTRVFELRGGSDAVIVGGNTVRQDDPRLTARHGQGHTPTRIVMTQSLDLPEKANLWDVSEVSTIVVTQRGARKSFQKLLASKGVEVVEFDMLNPREVMEYFHLRGYLSILWECGGTLAASAISSSVIHKVVAFVAPKIIGGSKAPSPVGDLGMVEMTQALNLIDVCYEQVGPDMLVSGFLQPIPDLLPVIPSEDATVEIDPSVDPFEPSIIFFYKTWDLYGMWNITIRYHTTVHVKWYLALSKKHNLLILHPKTLKANKFVGVENPKAYDCVEKIRTARSPEEAALIGRSTLRQKPELVRNDWEDVKIEVMYKALKCKFSTYPHLKSMLLSTIGTVLVEASPHDLFWGGGREGEGLNYLGRLLMQLRSEYLGESSVSAEKTSSA