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pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Length
467 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
51.76 kDa
Sequence
MPDIHIKNTRIYYNNSLRPAEILIENGKITKIGKDFRVSSSDMVIDAEGALTLPAGIDVHVHFREPGMTLKENWYTGSCAAAAGGIATVIDQPNTIPPTTDRRSFEQKLKLARKKSIVDFGINGGVTGNIEKLRELWRLGVTAFGEIFMAESTGGLNINEETFEEALAEIKKLGALATIHAEDEKMRLELEQLLKGDVSYDYHSKVRPNACEASAVQSALELISRLQVRAHFCHLSTLEAVGMIRKEKYLAKRENKKPLFTCEVTPHHLFLSAKDWERLRAFGKMNPPLRGSHSIKALVNGLNDGTIDMVASDHAPHLESEKDLDIRAAPSGVPGVETLMPLMLAAVRKNILPLSQMIMVTSWNPAKAFGLDRLGKGWLEVGFDADLMIVDPRNLQPIRADMLHSKAGWTPFEGMDAVFPEYTLSRGEVIWMEDSINAKPGRGEFLEGSGKRSEEDEEENSEETGSD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Putative dihydroorotase
Organism
Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)
Length
456 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
48.514 kDa
Sequence
MVVGQRERKRRCIRGEPLMNDTTWVLDGGRLIDPANGIDRIARLVLHEGKVHSIDTPDGDVPPDAGRLDVTGKIVAPGLVDLATELREPGSEEDETIQTGSNAALAGGYTTVLCCSSTKPLMDSAASVQLVRQIAQRVDGVRVLPIACLSKGRQAEQMAELGILAAAGAAGFSDTPRPMPNDALLKRALDYCRMFDLPIFDRPEVPELADGGVMHDGQIGLILGLKGLPTEAEDLAVARDVRLAEATKGRLHVGPVSTMGSIDMIGRVKSRGIHISASVCPHNLFGSDELLRSYDSRYKVHPPMRSPSHVEALRNAVAEGVIDAIESGHMPRAQEKKANDLDLAPFGASALETTLAAIATDLVETKILPWSRAIECLSTAPARIAGVKGGTLSVGANADVTVIDPLNAWSVEAKEFRSRCHSSPMTGRTLTARVTHTLVGGRLKFELHPTVASAAS
Protein
Putative dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Length
456 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
50.331 kDa
Sequence
MPDIHIKNTRIYYNNSLQPAEIIIEHGKITKIGKDFRVSSSDMVIDAKGSLTLPAGIDVHVHFREPGMTLKENWYTGSCAAAAGGIATVIDQPNTIPPTTDRRSFEQKLELARKKSIVDFGINGGVTGNIEKLKELWRLGVTAFGEIFMAESTGGLNIKEEDFEEALAEIKRLGALATIHAEDEKMRLELEQLLKGDVSCDYHSKVRPNACEASAVQCALEIISRLGVKAHFCHLSTLEAVGMIRKEKYLAKRENKEPLFTCEVTPHHLFLSTRDWERLGVFGKMNPPLRGSHSIKALVNGLNDGTIDMVASDHAPHLESEKGPDIRAAPSGVPGVETLMPLMLAAVRKNILPLAKMIMLTSWNPARAFGLDLLGKGKLEVSYDADLMIVDPRNLQPVRADMLHSKAGWTPFEGIDAVFPEYTLSRGEVIWMEESINAKPGRGKFLEGKGKMSEED
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Ehrlichia canis (strain Jake)
Length
447 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
49.115 kDa
Sequence
MYKQSWKLLGRGQDADFTVAYINARIIDPESKLDIIGSLLTKGDKIVDFGQDLFNNGIPSTIDEVVDCNNNILMPGLIDIHVHFREPGQEHKETIHTGSKSAAAGGVTTVVCQPNTIPTISSIITAKYIKMRALESAYVNIEFYASITKPDNSLSDMALLKEAGAVGFTDDGMPVMNSLTMRQALSYSSMLDTVVAQHAEDLNLSNNGHINEGTVSYELGLKGIPDISESIIVNRDIALMKNIKNVHYHILHVSSQDSLNIIKQAKNQGLKVTCEVTPHHLTLTEQDVITHGTLAKINPPLRTENDRLSMVEGLKNGIIDCIATDHAPHEVNTKELPLDTAAFGIVGLETMLPISLELYHNGTISLIDLLATLTYKPANIIKVPRGRIKKGFVADLIILDLNHEWTIDILKFASKSKNSPFHNRKVKGKVLRTIVSGKTTYTAVRNI
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Ehrlichia chaffeensis (strain ATCC CRL-10679 / Arkansas)
Length
447 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
49.167 kDa
Sequence
MYKQSWELLGNGQHADLTVAYINARIIDPESKLDIRGSLLTKGDKIIDFGPDLFANGIPSTIDEVIDCNNNILLPGLIDIHVHFREPGQEHKETINTGSKSAAAGGITTVVCQPNTIPTISSVITAKYIKMRALESAYVNIEFYASITKSDNSLSDMALLKEVGAVGFTDDGMPVMNALTMRQALSYSSMLDTVIAQHAEDLNISNNGCINEGIISYELGLKGIPDISESIIVNRDIALMKNIKNVHYHILHVSSQESLHIIKQAKSQGLKVTCEVTPHHFTLTERDIMTHGSLAKMNPPLRTENDRLSMIEGLKSGIIDCIATDHAPHDINAKELPLDTAAFGIVGLETMLPISLELYHNGTMPLIDLLATLTYKPADIIKVPRGRIKKDYVADLIILDLDHEWVVDISKFASKSKNSPFHNRKVKGKVLRTIVSGKTTYKAEIII
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Length
447 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
47.827 kDa
Sequence
MVDSNTQYPETGALAPAPADSLLISNVLVYGEGEPTNVFVKDGVIAAIGGTHEADRTIDGNGGVLLPGFVDMHVHLREPGREDTETIATGSAAAAKGGFTAVFTMANTTPVMDQPVIAESVWFKGQNIGLCDVHPVGSITKGLEGKELTEFGMMARSEAKVRMFSDDGKCVDDPQVMRRALEYAKGMDVLIAQHAEDHRLTEGASAHEGENAARLGLRGWPRVAEESIVVRDAIMARDYGNRVHICHASTEGTVELLRWAKSQGIPITAEVTPHHLTLTDERLETYDAVNKVNPPLRESRDAEALKKALLDGTIDVVATDHAPHGSEDKCCEFENAKPGMLGLETSLSIIVDTFVATGLADWRFVARVMSERPAEITRLPGQGRPIAEGEPANLAIVDPGKTWTASGADFASKAENTPFEGQEFSAKVTHTVLRGKVTCADGVAQNA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Anaplasma phagocytophilum (strain HZ)
Length
447 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
48.529 kDa
Sequence
MVSERQTWSLLQGGQCNEYTVAYINARIIDPASGTDYKGYLLTRGKEILDFGPGFFDPNGAAFAASEVVDCNGHVLMPGIVDLHVHLREPGGEHKETVDTGSRAAAAGGVTTVVCQPNTIPRLENVLVAKYLKMRALESSCVNIEFYGAVTKSDGELCDMASLKDAGALGFTDDGLPVMNALYMKRAFEYAQDLDVVVAQHAEDCNLSDGGCINEGLVSRELGLKGIPDISESIMVSRDIQLLREVPGAHYHVLHISTKKALDIVRAAKREGLRVTCEVTPHHFLLNESAVLEHGTMAKMNPPLRTEEDRLSMISGLEDGTIDCIATDHAPHAAQEKTRPISCCAFGIVGLETLLPLSLELYHNAGMSLMDVLSKLTSKPAEIVRLPRGKIAKGLVADLVIFDLEHVWTIDTAKFSSKSKNSPFQGRKVKGKVLRTVVSGKTVYRAE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Wolbachia sp. subsp. Brugia malayi (strain TRS)
Length
443 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
48.472 kDa
Sequence
MTQTWNLLQAGQERNYKVAYINARIIDPETKLDIEGSLLTEGSKIIDFGESLFSNGVPSGVDETINCEGLVLMPGLVDIHVHFREPGQEHKETIYTGSKSAAAGGVTTVVCQPNTTPAIDSVILAKYLKYRALETSHVNIEFYAKITTSEEKLTEVALLKEAGAVGFTDDGIPVMNPMIMRQALLYSSMLNVPIAQHAEDLNLSAGGAINEGKISEALGVKGILSASESVMVSRDILLMKDIENVHYHILHISSKDSLDAVKRAKDLGLNVTCEVTPHHFTLTEDIVKQHGAIAKMNPPLRTEEDRLAMVEGLKTGVIDCIATDHAPHDRSSKDLPLESAAFGIVGLETMLPLSLELYHSGQIDLFDILAKLTYKPADIIHVPRGRVQKNFVADLTLVDLNYEWEIKIDSFASKSKNSPFGGRKVKGRVVRTIVSGKTVYSQK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Wolbachia sp. subsp. Drosophila simulans (strain wRi)
Length
441 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
48.318 kDa
Sequence
MTQTWNLLQTGQKEGYKIAYTNARIIDPETKLDIKGSLLTEGDKIVDFGESLFSTSGVDETIDCKGLVLMPGLIDIHVHFREPGQEHKETIYTGSKSAAAGGVTTVVCQPNTIPAIDSVVLAKYLKYRALETSHVNVEFYAKITTLEEKLTEMALLKEAGAVGFTDDGMPVMNPMIMRQALLYSSMLGVPIAQHAEDLNLSAGGAINEGKISEELGVKGILSASESVMVNRDILLMKDMENVHYHILHVSSKDSLDAIKRAKDLGLNVTCEVTPHHFTLTEDIVKQHGAIAKMNPPLRTEEDRLAMVEGLKTGVIDCIATDHAPHDRSSKDLPLENAAFGIVGLETMLPLSLELYHSGQMGLLDVLAKLTYKPADIIHIPRGRIQKNLAADLILVDLNHEWEIKTDNFASKSKNSPFDGRKVKGHVVRTVVSGKTIYSQKS
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length
439 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
47.298 kDa
Sequence
MKKGKADPCNYLFRRARVIDPARDLDAVADVLVVDGILTDIKPNIDLPSDRLAHFAVIDASEKWIVPGLIDMHVHLREPGEEYKETIATGTMAAVAGGYTAVACMPNTKPVNDCAAVTEYILERAREQGHCRVLPVGAVSSGLEGRSLAEFGELKGSGAVAVTDDGRPVANSMLMRRALEYAKNFDLPVISHAEDPALSEGGLMNEGPTSTLLGLHGIPKAAEEVMVARDLALAELTGARLHIAHVSTAGAVRMIGEAKSRGVPVTAETAPHYFTLTDDRLMTFDTLYKVNPPIRGPADVEAIKRGLADGTIDAVATDHAPHSSIEKDTEFEYAANGIIGLESALPLILELVREKTLTPSQAVAKVSCNPARILGLPLGTLLLNQRACMTYLDPEFYFVLDCTTFRSKSRNCPFHGQPTRGRALMTFFNGKVAFSRLSK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
Length
439 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
47.039 kDa
Sequence
MSTLFLNARLLNPAENLDTVGSIKIGDDGLIEAVATGGESIPAKAEDNVIDLAGKVLAPGLFDMHCHFREPGQEYKETLETGSAAAVAGGFTGVALMPNTRPVIDSPLGVAYIRHHSAGLPIDLEVIGAMTVESRGEALAPYGKYASYSVKAVSDDGTAIQSSQIMRLAIEYAANFDLLLIQHAEDKHLTAGGIMNDGAVSAMLGLKGIPEVAEPIMIARDLQLIAWLKKHKLNGAVAEPRYHVAHISTAESVALVRKAKAAGLKVTCEVTPHHFTLTEHDLSSSIEKGNFIMKPPLASVENRDALIEGLRDGTIDAIATDHAPHAKHEKECPPDQAAFGIIGLETSLGLTITELVDKGVITLSQAIELLSTNPRRIMGLETILFRAGRKANLTIIDPDCEWIVSESDFGSKSRNTPFMGRKLKGRALGIYHNSKLIMR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Leifsonia xyli subsp. xyli (strain CTCB07)
Length
438 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.446 kDa
Sequence
MSDETFVITGAMLADGSRTDLLLAGGRIQETGVRLSAAGATVVDADGLLALPGLVDLHTHLREPGYEQSETVLTGTRAAAAGGFTEVFAMANTSPVADTAGVVEQVLSLGEAAGYATVRPIGAVTVGLEGERLAELGAMADSRARVRVFSDDGKCVSDPLLMRRALEYVKAFDGVIAQHAQEPRITAGAQMNEGALSGELGLAGWPAVAEESIIARDVLLAEHVGSRLHVCHVSTAGSVDVIRWAKARGIDVTAEVTPHHLLLTEELVSGYDARYKVNPPLRRSEDVEALRAGLADGTIDIVATDHAPHPVEAKDCEWDAAAFGMVGLESALSVVQSSVVDTGMLGWADIARVLSATPARIGRLAGHGTPVEAGAPAELFLYDPAAAREFSTGELAGKGVNSPYLSMTLSGRVVATFHRGYATVLDGAVLESVGGARG
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length
436 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.111 kDa
Sequence
MSTRSGSAAELAIRGAHVVDPSSGLDGVTDVVVRGGRVAAVGRGRPAARELDASGLFLFPGFVDLHAHWRTPGREDEEDLESGSSAAAAGGFTGVVMMPNTDPVLDRPALVSGLVRRAERESRVRAFVAAALHAGLAGERLTEMRLLKEAGALCVSDDGLGTQSAGVLRNGMLYARSAGLPVILHCEDRTLATGAVHEGAAAALAGVPGTPASAEDVATAAALVLAAETGARVHITHVSTALSAALVGFFRGRAAVTADTTPHHTTLTDELVFALDGLFRVNPPLRPGSDREGVVGALRDGILDFVATDHAPHAPEEKELPLEEAAPGFLGHETAFAALYTGLVLEGRLSLGRLVEAMSCGPGRWVGGLGSLSPGSPADLALVDLGEEWTVSRRTLASRSSNSPYLGRRLRGRVVGTMVGGEMVYDRMGARLGVRT
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258)
Length
433 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.605 kDa
Sequence
MSDVLFIEGGRVIDPASGVDGVRTVVIRDGKVAEVAERVERPRDARAVDARNRWVTPGFVDLHVHLREPGQEYKETVATGARAAVAGGFTAVCAMPNTKPVNDCAAVTELVLARAAAAGLARVYPVGAISRGSNGEELAEYGELKASGCVALSDDGRPVMSSALMRRALEYARAFGLPLTVHEEDLHLVGKGVMHEGAAATRLGLKGIPSQAEDVMVLRDIALVELTGGRLHVAHVSTAGAVRAIREAKRRGLPVTGEVTPHHLALTDDDVGASGYSTDFKMNPPLRSAEDVRACREALADGTLDAIATDHAPHSAVEKDVEFDAAANGIVGLETAFSVCLGLVREGALTERRLVEALTVGPARVFGLPAGTLARGAAADVAVLDAAAEWTVDPARLHSKGRNTPWKGRRLAGRCTHTIVGGRIVHEEDKADR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Anaeromyxobacter dehalogenans (strain 2CP-C)
Length
433 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.437 kDa
Sequence
MSDVLFIEGGRVIDPAGGVDGVRTVVIRDGKVAEVAERVERPRDARVLDARNRWVTPGFVDLHVHLREPGQEYKETVATGARAAVAGGFTAVCAMPNTKPVNDCAAVTELVLARAAAAGLARVYPVGAISKGSGGEELAEYGELKASGCVALSDDGRPVMSSALMRRALEYARAFGLPLTVHEEDLHLVGKGVMHEGAAATRLGLKGIPSQAEDVMVLRDIALVELTGGRLHVAHVSTAGAVRAIREAKRRGLPVTGEVTPHHLALTDDDVAASGYSTDFKMNPPLRSADDVRACREGLADGTLDAIATDHAPHSAVEKDVEFDAAANGIVGLETAFSVCLGLVREGALTERRLVEALTAGPARVFGLPAGTLARGAAADVAVLDAAAEWTLDPARLQSKGRNTPWKGRRLAGRCTHTIVGGRIVHEEGKADR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Anaeromyxobacter sp. (strain K)
Length
433 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.505 kDa
Sequence
MSDVLFIEGGRVIDPASGVDGVRTVVIRDGKVAEVAERVERPRDARAVDARNRWVTPGFVDLHVHLREPGQEYKETVATGARAAVAGGFTAVCAMPNTKPVNDCAAVTELVLARAAAAGLARVYPVGAISRGSNGEELAEYGELKASGCVALSDDGRPVMSSALMRRALEYARAFGLPLTVHEEDLHLVGKGVMHEGAAATRLGLKGIPSQAEDVMVLRDIALVELTGGRLHVAHVSTAGAVRAIREAKRRGLPVTGEVTPHHLALTDDDVGASGYSTDFKMNPPLRSAEDVRACREGLADGTLDAIATDHAPHSAVEKDVEFDAAANGIVGLETAFSVCLGLVREGALTERRLVEALTVGPARAFGLPAGTLARGAAADVAVLDAAAEWTVDPARLHSKGRNTPWKGRRLAGRCTHTIVGGRIVHEEGKADR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Elusimicrobium minutum (strain Pei191)
Length
432 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.43 kDa
Sequence
MKYLIKNAHVIDPANKIDGLKDILIENGKIAAVENKIEDNAAKIIDAKGLTAMPGFVDMHTHLREPGQEGKETIFTGTKAALKGGFTTVCMMPNTNPAMDSKNNLAIAQDIIRKTANVNVEIMGAITKNRAGKELSNFAELKQAGAIALSDDGSGVEDDAVMQAAFKESVKQDILLISHSEDSKLSAGGVMNEGLISTKLGLKPISNASEYEMVKREIQLAKGLDAKIHIAHVSTKESCEIIAKAKKQGVMVTAEATPHHFTLTDKACESFSGNTKMNPPLRSEADVEALKQALKDGTIDAIATDHAPHAVHEKEVEFDLAYFGIIGLETAFPLAYDVLVKSGLIDMAKLVGLMSLNPSKILGLKKGTLTPGADADITIVDLNKQWVYSKEEVQSLSCNSPFIGKNLQGYIEYTFVGGELKLENGTLKVKDA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Length
431 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
47.946 kDa
Sequence
MFDLSLENCRVDRDLTVNIGVDDGKIVQISRGRIDASEKIDLKGYFVLPGLIDAHVHFRDPGLEYKEDFRTGSMAAAHGGFSTVLDMPNTVPPADNAAEFERKIRIGERKSVVDFGLHAGFRSVSDVKGILRFMPASFKVFMDLTGISTVDGLFRELKDLSAPVPVTVHCENRDVVMKSMKELKDRSDPSAYALARPPLAEEVSVAEVLALSIHHEHPVHICHLSTVKALQLVEPFREYVTCEVTPHHLLLDSGAFRRFGTMVKTNPPLRPPESRIYPEFLDRINIIGTDHAPHGIEEKRKGIWDAPPGIPNLEVVLKLLLTLVSKGRMSLSTIRRMLAEEPARIFGLRSKGRIAEGMDADFTVIDLKETGRIRSDEFYSKAHYTPFEGFSYTGGPVMTIVRGRAVMRDGEVLEGNGRYIPAEHDGKHGSA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E)
Length
431 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.901 kDa
Sequence
MRMIIKNGTVIDGFGSEATADILIDYGIIKAIDKNIQVSDGIVIDATGKYVLPGFVDMHTHLRQPGFEEKETIKTGTEAAATGGYTTVACMPNTNPPIDNEIVVEYVKSIAQREGVVKVLPIGAMTKGMKGEEITEMAKLKKAGVVALSDDGFPIMSAGLMKRIMTYGKMYDLLMITHCEDKALSGEGVMNSGVISTMIGLKGIPREAEEVMLARNIILAKSTGVRLHIAHISTKGSVELIREAKEKGVKITAEVTPHNLTLTDEAVYNYDTNTKAYPPLRTREDIEALIEGLKDGTIDAIATDHAPHTKDDKKVPYDMAAFGISGLETAFSVINTFLVQTGKITIKELVNYMSINPAKILGISSGIKVGSIADIVIVDPYEEYVVDKDKFKSKGKNTPFHGMRLKGVVDCTIVEGEIKYKKDRKTEKVEV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Thermoanaerobacter sp. (strain X514)
Length
431 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.901 kDa
Sequence
MRMIIKNGTVIDGFGSEATADILIDYGIIKAIDKNIQVSDGIVIDATGKYVLPGFVDMHTHLRQPGFEEKETIKTGTEAAATGGYTTVACMPNTNPPIDNEIVVEYVKSIAQREGVVKVLPIGAMTKGMKGEEITEMAKLKKAGVVALSDDGFPIMSAGLMKRIMTYGKMYDLLMITHCEDKALSGEGVMNSGVISTMIGLKGIPREAEEVMLARNIILAKSTGVRLHIAHISTKGSVELIREAKEKGVKITAEVTPHNLTLTDEAVYNYDTNTKAYPPLRTREDIEALIEGLKDGTIDAIATDHAPHTKDDKKVPYDMAAFGISGLETAFSVINTFLVQTGKITIKELVNYMSINPAKILGISSGIKVGSIADIVIVDPYEEYVVDKDKFKSKGKNTPFHGMRLKGVVDCTIVEGEIKYKKDRKTEKVEV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)
Length
431 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
47.024 kDa
Sequence
MRIVIKNGIVIDGFGGEEKADILINYGIIKGIDKNIDVSDAIVIDAEGKYVLPGFVDMHTHLRQPGFEEKETIRTGTESAAAGGFTTVACMPNTNPPIDSEVVVEYVKAVAQREGVVKVLPIGAMTKGMKGEEITEMAKLKKAGVVALSDDGFPIMSAGIMKRVMTYGKMYDLLMITHCEDKTLSGEGVMNSGIIATMLGLKGIPREAEEVMLARNIILAKATGAKLHIAHVSTKGSVELIRRAKEEGVSITAEVTPHHLTRTDEAVYNYDTNTKVFPPLRTREDVEALIEGLKDGTIDAIATDHAPHTKDDKKVPYDMAPFGISGLETAFSVINTFLIQTGIITMKALVNYMSMNPARILGISNGIRVGATADIVIVNPHEEYTVDKEKFKSKGKNTPYHGMKLKGVVEYTIVEGQIRYQKNKKFEKVEI
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Length
430 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.439 kDa
Sequence
MTTLIKNAQVWQAGQLQTTDILIAEGRIKAIGHQLHDQFGPADHVICADQHFVSPGFVDVHVHLRDPGQTAKETIATGTLAAAHGGFTTVGAMPNVDPVPDTPERVATMVARNQQEAHVHVAQYASITTGRTSEQLVDFAGIKAAGAFAVSNDGSGVQTAGTMFAAMQGAAKVGLPLAAHVEDDSLYHHGVMNAGPVADRLGLPGINNVSEAAQVARDVMLAEASGVHYHVCHVSTAESLRVIRNAKAAGINVTCEVSPHHLLLCDEDITMDNPMLKMNPPLRSAKDRAALVAGLLDGTIDMIATDHAPHTDAEKQGSMKTAAFGITGIETAFATLYTALVKTRLLTLGRLIELMSTRPAELFGLNTAGRLVVGAPADLTIIDLDHQYEIEAATMLSKGHNSPFIGWPVYGNVLMTLVDGKLAYGKETQA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Length
430 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.24 kDa
Sequence
MSVLIRGVRPYGEGERVDVLVDDGQIAQIGPDLAIPDTADVIDATGHVLLPGFVDLHTHLREPGREYAEDIETGSAAAALGGYTAVFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTVGLAGAELTEMGMMNAGAAQVRMFSDDGVCVHDPLIMRRALEYATGLGVLIAQHAEEPRLTVGAFAHEGPMAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASAAGTVEILKWAKDQGISITAEVTPHHLLLDDARLASYDGVNRVNPPLREASDAVALRQALADGIIDCVATDHAPHAEHEKCVEFAAARPGMLGLQTALSVVVQTMVAPGLLSWRDIARVMSENPACIARLPDQGRPLEVGEPANLTVVDPDATWTVTGADLASRSANTPFESMSLPATVTATLLRGKVTARDGKIRA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Mycobacterium leprae (strain TN)
Length
430 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.186 kDa
Sequence
MSVLLRGVRLYGEGEQVDVLVEGEQIANIGAGIDIPDTADVIDAIDQVLLPGLVDLHTHLREPGREYAEDIETGSAAAALGGYTAVFAMPNTTPVADSPVVTDHVWRRGQQVGLVDVHPVGAVTVGLAGAELTEMGMMAAGAAQVRIFSDDGNCVHNPLVMRRALEYATGLGVLIAQHAEEPRLTVGAVAHEGPTAARLGLSGWPRAAEESIVARDALLARDAGARVHICHASTAGTVEILKWAKEQGISITAEVTPHHLLLDDSRLASYDGVNRVNPPLRETADAVALRQALADGIIDCVTTDHAPHADHEKCVEFSAARPGMLGLQTALSVVVHTMVVPGLLSWRDVAQVMSENPARIAGLPDHGRPLEVGEPANLTVVDPDVTWTVTGDGLASRSANTPYEAMTLPATVTATLLRGKVTARGQKSPV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
430 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.192 kDa
Sequence
MSVLIRGVRPYGEGERVDVLVDDGQIAQIGPDLAIPDTADVIDATGHVLLPGFVDLHTHLREPGREYAEDIETGSAAAALGGYTAVFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTVGLAGAELTEMGMMNAGAAQVRMFSDDGVCVHDPLIMRRALEYATGLGVLIAQHAEEPRLTVGAVAHEGPMAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASAAGTVEILKWAKDQGISITAEVTPHHLLLDDARLASYDGVNRVNPPLREASDAVALRQALADGIIDCVATDHAPHAEHEKCVEFAAARPGMLGLQTALSVVVQTMVAPGLLSWRDIARVMSENPACIARLPDQGRPLEVGEPANLTVVDPDATWTVTGADLASRSANTPFESMSLPATVTATLLRGKVTARDGKIRA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
430 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.192 kDa
Sequence
MSVLIRGVRPYGEGERVDVLVDDGQIAQIGPDLAIPDTADVIDATGHVLLPGFVDLHTHLREPGREYAEDIETGSAAAALGGYTAVFAMANTNPVADSPVVTDHVWHRGQQVGLVDVHPVGAVTVGLAGAELTEMGMMNAGAAQVRMFSDDGVCVHDPLIMRRALEYATGLGVLIAQHAEEPRLTVGAVAHEGPMAARLGLAGWPRAAEESIVARDALLARDAGARVHICHASAAGTVEILKWAKDQGISITAEVTPHHLLLDDARLASYDGVNRVNPPLREASDAVALRQALADGIIDCVATDHAPHAEHEKCVEFAAARPGMLGLQTALSVVVQTMVAPGLLSWRDIARVMSENPACIARLPDQGRPLEVGEPANLTVVDPDATWTVTGADLASRSANTPFESMSLPATVTATLLRGKVTARDGKIRA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Caldicellulosiruptor bescii (strain ATCC BAA-1888 / DSM 6725 / Z-1320)
Length
430 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
47.442 kDa
Sequence
MILIKNAQIVNSIDNKLEKADILIVDDKIEKIGKNIEENPDKMIIIDTSGKYVMPSFTDIHCHLREPGFEYKEDIKSGSRAALAGGFTTICCMPNTNPPVDNRAMIAYIKYRAKEVSPIEVLPVGAITKGLSGEELAEIGFIKEEGAIAISDDGKCVMNANIMRNALLYSKDFSIPVISHCEDTNLSEGGQINLGYVSTITGLRGIPREAESIIVARDILLAKETKAHLHITHVSTKESVRLIKMAKEWGVNVTADTCPHYISLTEEEVLGFNTNAKVNPPLRTQEDIEALIEGLKEGVIDCISTDHAPHHKDEKNVEFNLAASGTIGFETAFSVLFTYLVEKNGFDIGKIVELLNYNPRKIIGLSPNIIKEGEKANLVIVDLKKKWEVKEENIVSKSKNSVFLGKLLTSYVETVIYNGKILKKDGVLSC
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T 6331)
Length
430 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
47.394 kDa
Sequence
MILIKNAQIINSLHDKVEKADILIVDDKIKKIGKDIEENPEKMTIIDASGKVVMPSFTDIHCHLREPGFEYKEDIKSGSRSAAAGGFTTICCMPNTNPPVDNRAMVAYIKYRAREVSPIEVLPVGAITKGLLGEELAEIGFMKEEGAIAISDDGKCVMNANLMKNALLYSRDFSIPVISHCEDTNLSEGGQINLGYVSTITGLRGIPREAESVIIARDILLAKETKSHLHITHVSTKESVRLIKMAKEWGVNVTADTCPHYISLTEEEVLGFNTNAKVNPPLRTQEDVEALIEGLKEGVIDCISTDHAPHHKDEKNVEFNLAASGTIGFETAFSVLFTYLVEKNGFDIGKIVELLNHNPRKIIGLSPNVLKEGEKANLVIVDLKKKWEVKEENIVSKSKNSVFLGKLLTSYVETVIYNGKILKKDGVLNC
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)
Length
430 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
47.093 kDa
Sequence
MGMLIKNGNVVMVEDGKIRKMDVLIDKGIIVEISPEINRSDVEVIDIEGKFLIPGLIDMHVHFRDPGYTHKEDIHSGSNAALAGGFTGVLMMPNTDPPPDNATVIYYWKEKSKSIPLNILFSGCITKNRAGKELSKFYELKEAGAVAITDDGNWVADGAVFRHAMEYAAALDLLVITHPEEPTIANRGVINEGYWSTVLGLRGIPKAAENIAIYRDIEIAKMTGAKLHVAHLSTAEGVRLVAAAKKLGLKVTAEVTPHHLVLTDEALAGYDTNLKVNPPLREAEEQKALLKGLLEGVIDVIATDHAPHASYEKNVEFNDAPFGIEGLETAFPVLYTELVLKKKITLEKLLLKMTVNPAKILQLPKQGDIKKGNYANLTVIDPKLTLKVSEELLVGKSKNNPFLGRTLTGWPVMTVYQGIVAYQRLLKGVQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Solibacter usitatus (strain Ellin6076)
Length
430 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.654 kDa
Sequence
MPIVIRNGRVIDPASNTDRVADVFIVDGRIAGVAPNLSSPKAEVFDATGMIVAPGFIDMHVHLREPGFEHAETIESGSRAAAAGGFTSICCMPNTKPVNDSAMVTSYIVEQARSKAAVNVFPIGAITKGSAGEELAAIGAMKAAGAVAISDDGLPVMNARVMRRAMEFARSYDLPIIQHCEDLNLSAGGDMHEGANSVRWGLRGIPAASEDVMVARDLVLAQLTGARYHVAHISTRNAVAMVEYGRSHGLPVTCETTPHHFGLADADMAPYDSNYKMKPPLRSCGHRDAIIEGLIAGTISAIATDHAPHPGSEKMQEFERCPFGIIGLETALALALEELVAPGKITLARLIELFTTGPESVMRLGRGTLTPGAPGDVTVFSPTVEWTYDVNQSASRSRNSPFHARTFHGGPMATIVNGGLKWSRQSSHIT
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lactobacillus fermentum (strain NBRC 3956 / LMG 18251)
Length
429 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.146 kDa
Sequence
MKTLIKNGTVYNDGRLVKEDVLVEDGIIRAIGKDLHEYLDDDYDELDAGNLLVSPGLVDVHVHYREPGQTEKETIKTGSAAAAHGGFTTVGAMPNVDPVPDTPAKVAQMVAKNKQDGLVHIAQYSAITTDRTSDEVVDMAGVKQAGAFAVSNDGNGVQAAGTMYRAMQAAKAVGLPLAAHVEDESLLFGGVMTEGDRSRYLGLPGAPEVVESAQVARDLALAKATGVHYHVCHVSTKDSLAMIHFAKQNGVRVTCEATPHHLLLSDQCIDGHDSNYKMNPPLRHEADRRALVAALNDGTVDMIATDHAPHTEEDKGRDFCCAANGITGSETAFALLYTKLVKTGLLKLERLLDLMATNPAEAFNLTEAGHLEVGKPADIAVFDLNHPYVIDQRDYLSKGINSPFTGMTVYGQTVMTMVDGQVVYQRKEN
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lactobacillus salivarius (strain UCC118)
Length
429 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.735 kDa
Sequence
MATLIKNGNLYQAGRIYQADVLIEDGKIKAIGKNLSDVVKENLVEIDATNKLVAPGLVDVHVHYRDPGFTYKETIHTGSLAAAHGGYTTVCAMPNLDPVPDTPELVEKMCSRNQEDGVVKVKQYGSITHGLKSEELVDFVGMKKAGAFAFSNDGSGVQTAGTMYQAMKSAAALNMAIVAHVEDNSLLFGGVMNAGKRADELGLPGILGISESSQIARDLLLAKETGVHYHVCHVSTKESVELVRLAKQHKINVTCEVSPHHLLLADVDIPGNDPYYKMNPPLRGVEDRQALIDSLLDGTIDMIATDHAPHSIDEKTGDMREASFGITGSETAFAMLYTKFVKTGIFTLEQLLQWMSINPAEKFGMEDAGELLPGKSADLAIFDLNKEYVIKEEDYLSKGINTPFTGEKVYGQTVLTMVDGQKVYQREEK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lactobacillus sakei subsp. sakei (strain 23K)
Length
429 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.772 kDa
Sequence
MYRLIQNGQLLIDDQLVKRDIAIDEKGRITAIEAQITPTDEPTETIFDAQGALVSAGLIDGHVHFRDPGFTDKETLQTGSQAAAHGGYTSVIAMPNLNPVPDNLSDFKTLVARNQTETSVHTYQFAPITGDLVNNDLVDMPAFKAAGAAGFTNDGHGVQDAQTMYLAMQQAAAIDAPIVAHVEDISLVNGGVIHDGAAAKRLNVPGIPSVSESAQVARDIELARATGVHYHICHISTKETVALVRRAKADGVNITCEVTPHHLLLDDRSIISDDTMLKMNPPLRTLADRQSLWAGLMDGTIDVIATDHAPHTAAEKSQSLLQAPFGIVGSETAFSLLYTHLVVNGPFSLAQLLAKMTTVPAQVFNLPAAGQLRVGDQADIAVFNLTQPTTIQATDFQSKGHNTPFIGETVLGGTELTLVAGQVAYQRSK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
Length
429 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
48.832 kDa
Sequence
MSNLVLKNCKTIDNKIVNIIIENGIIKDIKKTILPSEKETDTICDIKENIIIPGLIDTHVHLRDPGMTQKETWTTGTQAAAHGGYTTIIDMPNTLPATDTKKAFQEKRNIATKKSYVDFGLHAGVKTRQDVMDIMSEKPASYKIFMDLYTNKQLDEMFNYVSQTNKPLSLHCEDKTLVDYNIKTMKKNPLNKNKTITYSYARSALAELIAVNRAIEFAKKYKLQLHLCHISTRQTLELIHEAKEKLNISIEATPHHIFLDNTTYERYGVKAKTNPPLRDSNYNITIDNLNEFDSIGTDHAPHTIEEKEKDTWKSAAGIPGLETALKLLLTEVNNKRLTLEQLVKLTSTNPANIFNIPNKGKIKKGYDADITVINMKETGKISIENTYTKAKYTPFENRDYVGSNIMTINRGNIISQDNDVYKYDSKYIY
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus cereus (strain AH820)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.656 kDa
Sequence
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHEALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus cereus (strain ATCC 10987 / NRS 248)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.568 kDa
Sequence
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRAADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus cereus (strain G9842)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.656 kDa
Sequence
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIEVNGNLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICSMPNTRPVPDCREHMEDLQKRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSVDPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus cereus (strain 03BB102)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.626 kDa
Sequence
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQVGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus cereus (strain B4264)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.597 kDa
Sequence
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQKRIEEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDANMMLAAMKRAAKLDMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGVITLEQLIQFLTEKPADTFGLEAGRLKEGRAADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus cereus (strain AH187)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.599 kDa
Sequence
MNYLFKDGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.65 kDa
Sequence
MNYLFKNGRYLNEEGTIVATDLLVQDGKIAKIAKNISAENAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDSKEHMEDLQKRIQEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSVDPNFKMNPPLRGREDQEALIEGLLDGTIDIIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLETGRLKEGRAADITILDLEQEEKIDPTTFLSKGKNTPFAGWKCQGWPVMTLVGGKIVWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus cereus (strain Q1)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.599 kDa
Sequence
MNYLFKDGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.57 kDa
Sequence
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQKRIEEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLDMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGVITLEQLIQFLTEKPADTFGLEAGRLKEGRAADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus cereus (strain ZK / E33L)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.598 kDa
Sequence
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.284 kDa
Sequence
MKTLIKNGSIVTKEGTVKTQDVLLHDGVISAIGLNLEETDAHVIEANGKLVTPGLVDLHVHLREPGGEAKETIETGTKAAAKGGFTTVAAMPNTRPVPDSAEQMSWLTGRIDETGVVRVLPYAAITTRQLGRELTDFAKLKEAGAFAFTDDGVGVQSAAMMLEAMKEAAKLEMAIVAHCEENTLIQNGSVHEGVFSKKHGIAGIPSVCESVHIARDVLLAEAAGVHYHVCHISTKESVRVVRDAKRAGIRVTAEVTPHHLLLCDEDIPGLDAHYKMNPPLRGKEDREALIEGLLDGTIDFIATDHAPHTEEEKGQGMERAPFGIVGLETAFPLLYTHFVKKGTFTLKQLVDWLTIDPAETFQLPYGRLEEGAPADVTIIDLEAERAIDPAHFASKGRNTPFAGWTCQGWPVATLVGGKLVWEEKEVAR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.626 kDa
Sequence
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFVGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.684 kDa
Sequence
MSYLIKNGFMLDEKGEKVQRDIRVEGDAISEIGSLEAASGETVIDADGLFVSPGLVDLHVHFREPGGEKKETIETGAKAAARGGFTTVAAMPNTRPVPDTKEQMEWLVNRIDETASVRVLPYASITIRQTGREMTDFEGLKDAGAFAFTDDGVGVQTAGMMYEAMKKAASINKAIVAHCEDNSLIYGGSVHDGEFAKANGLNGIPSVCEAVHIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKKAGIRVTAEVTPHHLLLSDSDIPGLDTNYKMNPPLRSPEDREALLEGLRDGTIDFIATDHAPHTEEEKQQTMSLAPFGIVGLETAFPLLYTHFVKTGKWTLKQLHDYMTVKPCEAFGLPYGKLEAGRSADITLIDLEREEKIDKSTFLSKGKNTPFDGISCFGWPAMTMAKGKLVYQEGRLVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus pumilus (strain SAFR-032)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.993 kDa
Sequence
MSYLIKNGFILTSTGEKVQQDIRVEGEVIQAIGHLEREDGEEVIDAKGLFVSPGLIDLHVHLREPGGEKKETIETGSKAAARGGYTTIAAMPNTRPVPDTKEQMEWLMNRIEETSSVRVLPYASITTRQIGEEMTDFAALKEAGAFAFTDDGVGIQTAGMMYEAMKKAASLDQAIVAHCEDNSLIYGGCVHEGEFSKANGLNGIPSICESVHIARDVLLAEAANCHYHVCHISTKESVRVVRDAKKAGIRVTAEVSPHHLLLCDADIPGLDTNYKMNPPLRGKEDREALIEGLLDGTIDFIATDHAPHTEEEKNETMQRAPFGIVGLETAFPLLYTRFVKTGEWTLKELVDYMTIKPAEAFSLPYGKLEKGQIADITLIDLNKEMAIDKKSFLSKGQNTPFDKLTVSGWPVMTLASGKVVYEEGRLVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus subtilis (strain 168)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.533 kDa
Sequence
MSYLIKNGWILNENGEKTQADIRVTGETITAIGKLDATDNETVIDAKGLLVSPGFVDLHVHFREPGGEKKETIETGAKAAARGGYTTVAAMPNTRPVPDTKEQMEWVQNRIKETSCVRVLPYASITIRQIGDEMTNFEALKEAGAFAFTDDGVGIQTAGMMYEAMKRAAAIDKAIVAHCEDNSLIYGGSVHEGTFSKANGLNGIPSVCESVHIARDVLLAEAANCHYHVCHISTKESVRVVRDAKKAGIRVTAEVSPHHLLLCDEDIPGLDTNYKMNPPLRSPEDRAALIEGLLDGTIDFIATDHAPHTEEEKNTEMKLAPFGIVGLETAFPLLYTHFVKNGSWSLKQLIDYMTIKPCEAFGLPYGTLQTGQAADITLIDLEKEAVIDKETFLSKGKNTPFNGISCTGWPVATIAAGKLAYEEGRLVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus weihenstephanensis (strain KBAB4)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.487 kDa
Sequence
MNYLFKNGRYMNAEGTIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCKEHMEDLQKRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRASKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAANCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLTEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Geobacillus kaustophilus (strain HTA426)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.177 kDa
Sequence
MGVWLKNGMSFNKDGELMRTHIKIEHGTIAAILYEQPLEANEEDVIDVGGRLIVPGLIDLHVHLREPGGEAKETIETGTLAAAKGGFTTVAAMPNTNPAPDRKEQMEWLQARIRETARVNVLPYAAITIGQKGEELTDFAALKEAGAFAFTDDGVGVQSAGMMFEAMKQAAALDMAIVAHCEDDTLTNGGAVHDGEFARRYGLRGIPSVCEAVHIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKRAGIRVTAEVTPHHLLLCDEDIPGLDANYKMNPPLRSREDRDALIEGLLDGTIDFIATDHAPHTAAEKAKGIEAAPFGIVGLETAFPLLYTHFVKTGVFTLKQLVDWLTIKPAQCFGLKAGRLAVGAPADIAVIDLETEEAIDPETFASKGKNTPFAGWVCQGWPVMTFVGGTLVWEKGRA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Geobacillus thermodenitrificans (strain NG80-2)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.453 kDa
Sequence
MAMWLKNGMSFNENGQLVRTHIKIEHGNIAAIHHEQLFEANGEDVIDVGGKLIAPGLIDVHVHLREPGGEAKETIETGTLAAAKGGFTTVAAMPNTNPVPDRKEQMEWLARRIQETAHVRVLPYASITLGQKGEELTDFAALKEAGAFAFTDDGVGVQSAGMMFEAMKRAAALDMAIVAHCEDDTLKNGGAVHDGDFARRYGIAGIPSVCEAVHIARDVLLAEATGCHYHVCHISTKESVRVVRDAKRAGICVTAEVTPHHLLLCDEDIPRLDANYKMNPPLRSRADREALIEGLLDGTIDFIATDHAPHTAAEKAKGMEAAPFGIVGLETAFPLLYTHFVKKNVFTLKQLVDWLTIKPAQCFGLQTGRLEVGAPADITVIDLETEEPIDPETFASKGNNTPFAGWRCQGWPVMTFVGGTLVWEKGRA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.465 kDa
Sequence
MKLLIKNGHVLDVKTGLDRVTDILAVDGIIHEVGSKIDEAGCEVIDATGLYVTPGLVDAHCHLRDPGYEYKEDIESGTRSAAKGGFTSVACMPNTNPVLDNEAMVKYVINKAKTDGFLNVFPIGALSKGLKGEELSEIGELKFAGAVALSDDGRPVGNSSLMKKAMQYASMFDITIISHCEDLDLVDEGLMNEGYQSSILGLKGNPAPAEEVMIARDLILAEYTKATIHIAHVSTELGVDLIRNAKRRGVKVTAETCPHYFTLTDNACEGFNTNAKVNPPLRTQKDVDAIIQGLKDGTIDIISTDHAPHHIDEKNVEFKIAANGMVGFETAFPLAVTYLVKPGHLSLKELVYKMSFNPSQMLGLNKGTIEVGKLADLIIFDLNEEYKVNITEFESKSKNSPFNGLLLYGQPQYTIVGGTPVVRKKVLL
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Anoxybacillus flavithermus (strain DSM 21510 / WK1)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.807 kDa
Sequence
MATIFKRVRLLNEQGELIQTDIKVAGGRIVQIAHDLHAEADDEVIDVDGQFVAPGFVDVHVHLREPGGEHKETIATGTLAAAKGGFTTIAAMPNTKPVPDTKQHMEWLVNRIRETAHVRVLPYASITVRQAGKQLVDFVALKEAGAFAFTDDGVGVQSARIMYEAMQQAAALDMPIVAHCEDETLTYKGCVHDGSFAKRYGLSGIPSVCESVHIARDVLLAEATGCHYHVCHISTKQSVRIVREAKQAGIRVTAEVTPHHLLLCDEDIPTLDANFKMNPPLRTKEDQQALIEGLLDGTIDFIATDHAPHTKEEKSEGMVLAPFGIVGLETAFPLLYTHFVEKGICTLKQLVDWLSKKPAETFRIDGGELKVGAKADFVVIDLHTEQAIDPNTFVSKGKNTPFAGWTCKGWPTMTIVAGKIVWQKGRGE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus anthracis (strain A0248)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.656 kDa
Sequence
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHEALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus anthracis (strain CDC 684 / NRRL 3495)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.656 kDa
Sequence
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHEALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus thuringiensis (strain Al Hakam)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.598 kDa
Sequence
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus anthracis
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.656 kDa
Sequence
MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHEALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Length
428 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.271 kDa
Sequence
MSKTLIRGAKVLGGEPQDVLIDGTVVEAVGTNLSAEGAEVVEADGKVLLPGLVDLHTHLREPGREDSETVLTGTRAAASGGYTNVFAMANTFPVADTAGVVEQVWRLGQESGYCDVQPIGAVTVGLEGAKLAELGAMHESAAGVTVFSDDGKCVHDAVIMRRALEYVKAFNGVVAQHAQEPRLTEGAQMNEGVVSAELGLGGWPAVAEESVIARDVLLAEHVGSRVHICHLSTAGSVEIVRWAKSRGIDVTAEVTPHHLLLTDELVRSYNPVYKVNPPLRTERDVMALREALADGTIDIVATDHAPHPHEDKDCEWAAAAMGMVGLETALSVVQETMVDTGLLDWAGVADRMSFKPAKIGQATGHGRPVSAGEPANLTLVDAAYRGQVDPAGFASRSRNTPYEGRELPGRVTHTWLRGKATLVDGKLT
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Enterococcus faecalis (strain ATCC 700802 / V583)
Length
427 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.058 kDa
Sequence
MKTLIKNGKIIKKENQLIEAALWLENGVIHAIGESFDEADFEQVFDANGQLITPGLVDVHVHFREPGFTYKETIKTGSKAAARGGFTTVCAMPNLNPVPDTAEKLSEVYDLIQKDAVVKVLQYAPITEELRSEVLTNQKALKEAGAFAFTNDGVGVQTAGTMYLAMKEAAALNMALVAHTEDESLLFGGVMHEGEVSKKLGLPGILSATEASQIARDITLAKETGVHYHVCHVSTEESVRVIRDAKKAGIHVTAEVSPHHLILVDEDIPGDEGFWKMNPPLRGLADRQALIDGLLDGTIDCIATDHAPHGLEEKQQSFLNAPFGIVGSETAFQLIYTNFVETGIFTLEQVIDWMAVKPAEIFGLNAGTLTIGAPADIAVFDLATAAPIDAEAFESMAVNTPFTGWTVKGKTLMTFVDGALAWSEEAQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lactobacillus leichmannii
Length
427 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.319 kDa
Sequence
MAILLKNGLVYQEGEFIKEDVLISGSKIQAIGLDLPEEGAEVYDLKGKLLAPGLVDIHEHYREPGFTYKETIKTGSEAASRGGFTTVCTMPNVDPIPDDLETFEKQVALNEANSCVHLKQYGAITEDLTSDKVVDMAALKEAGAFAFSNDGHGIQQAGTMYEAMQEAAKVGLAICEHIQDDSLYHHGVMNAGKKAEELGLPGILGVSESAQLARDLVLAQATGVHYHACHVSTKESVELIRIAKEYGINVTAEATPHHLLLSEEEIDGNNGYYKMNPPLRSKEDQFALIEGMLDGTIDLIATDHAPHSREEKAGDMRKAAFGIIGNETAFACLYTKFVKSGQMDLSLLLDLMSYQPAKLFGLDAGVLAPGKEADLAVFDLDHAEKLSEEDYLSKGVNTPFTGQEVYGMTALTFVSGKLVYKSKHFAD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Desulfotomaculum reducens (strain MI-1)
Length
427 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.864 kDa
Sequence
MRYLIKGGIVVDPVADTLTCTDILVEEGMIKEIGQLSDSEAEVIAAEGNYVCPGFMDMHVHLREPGYEYKEDIVSGTRAAAMGGFTSVACMPNTNPVADNAAIISHVLAKARNAAARVFPIGALTKGSLGKELTEMADLKGAGAVALSDDGMPVMNADIMLRVMQYASMLEMTVISHCEDNKLSEGGQMHEGAVSAMLGLKGIPSLAEEIMVARDILLSEYTGCRLHLAHISTEGSVRLVRQAKERGVPVTAEATPHHFTLTEEAVQGYSTNAKVNPPLRRQTDVEAIKEGLRDGTIDVIATDHAPHAYHEKDVEFQYAPNGMIGLETAVGLIFTQLVQPGILTVPQAVAKLTCNPHRVLGLSGGRLLPGTPANITIIDPKLSEVVDPTKLLSKSKNTPFGRWKLTGLPVLTMKDGLLVMRDRQLLE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pelotomaculum thermopropionicum (strain DSM 13744 / JCM 10971 / SI)
Length
427 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.76 kDa
Sequence
MKLLIKGGTVVDPVAGKIEEKDVFIVDGKIARAGAHVNTAGAEVLDASGKLVVPGLIDMHVHLREPGFEARETIYTGTRAAARGGFTSVACMPNTSPVADNGAVISFIKACGLKGAVNVYPIGAITRGSKGEELAEMGDMKEAGAVAFSDDGMPVMNAGLMRRALQYAGMLGMVVISHCEDKNLSAGGVMHEGYVSTMLGLKGIPASAEEVMVARDILLAEETGSRVHIAHVSTAGSVRLIREAKARGVRVTAEVAPHHFTLTDEAVLGYDTSTKVNPPLRSAGDVAAVREGLADGTIDVIATDHAPHTEEEKDVEYDLAPFGMVGLETAVGLVWTELVAAGVLTPLQAVVKMTLNPARVLGIPKGTLEPGADADITIIDPDLSEPVDPARFASKGRNTPFRGRLLKGLPWATIVGGRVVMQDRVIR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus caldolyticus
Length
427 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.048 kDa
Sequence
MGVWLKNGMSFNKDGELMRTHIKIEHGTIAAILYEQPLEANEDVIDVGGRLIVPGLIDLHVHLREPGGEAKETIETGTLAAAKGGFTTVAAMPNTNPAPDRKEQMEWLQARIRETARVNVLPYAAITIGQKGEELTDFAALKEAGAFAFTDDGVGVQSAGMMFEAMKQAAALDMAIVAHCEDDTLTNGGAVHDGEFARRYGLRGIPSVCEAVHIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKRAGIRVTAEVTPHHLLLCDEDIPGLDANYKMNPPLRSREDRDALIEGLLDGTIDFIATDHAPHTAAEKAKGIEAAPFGIVGLETAFPLLYTHFVKTGVFTLKQLVDWLTIKPAQCFGLKAGRLAVGAPADIAVIDLETEEAIDPETFASKGKNTPFAGWVCQGWPVMTFVGGTLVWEKGRA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Bacillus clausii (strain KSM-K16)
Length
427 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.862 kDa
Sequence
MAMKVTGGFILDENGEQVAKDVYIKDGKIVEHVADGDIRQQFDATGLLISPGFVDVHVHLREPGGEKKETIETGTKAAARGGFTTVAAMPNTRPVPDNAEQLDLLQARISETAVVRVLPYASITTRQLGQELTDFKALKEAGAFAFTDDGVGIQEAGMMLSAMKEAAALNMAVVAHCEDNSLINGGAVHEGHYAKAHGLNGIPSVCEAVHIARDVLLAEAAGAHYHVCHVSTKESVRTIRDAKKAGIRVTAEVTPHHLLLCEDDIIGKDPNFKMNPPLRAKEDRDALVAGLLDGTIDFIATDHAPHTAEEKSASLERAPFGIVGLETAFPLLYTHFVKPGTFTLKQLIDWLTVKPAQTFNLPYGTLQVGAAADLTLIDLKANETIDPSMFLSKGKNTPFAGWDCAGIPQATMVAGKTVYKKERITNE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Macrococcus caseolyticus (strain JCSC5402)
Length
427 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.665 kDa
Sequence
MSTLLRGGKVLVNDELVSKDIRIEDGKIVEMGEKLNVYNSEIIELDGKFVSQGFVDVHVHLREPGGEHKETIESGTRAAARGGFTTVCPMPNTRPVPDSVEHIEALNQSIKQHAKVRVLPYASITERQLGKDLVDFKALKEHGAFAFTDDGVGVQTASIMYEAMQQAAQLNMAIVAHCEDNSLIYGGAMHEGKVSKALNIPGIPSICEAVQIARDVLLAEAADCHYHVCHVSSKESVRVIRDAKRAGIKVTAEVTPHHLLLNETAITEDDAILKMNPPLRSEEDHQALIEALLDGTIDFIATDHAPHAADEKNQPMTKAPFGIVGSETAFPLLYTRFVKNGDWTLGQLIDYLALKPGQVFGLPYGKSLEVGSIADITVIDLDEKYEIKSEDFLSKSSNTPFIGEHVYGNVKLTLVEGQIAYQEGQHA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Geobacillus sp. (strain WCH70)
Length
427 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.398 kDa
Sequence
MAIILKNGKSFNKDGVIERTELKIENGFITAIGSKLHSEEADEVIDVQGKLISAGFIDLHVHLREPGGEAKETIATGTLAAAKGGFTTVAAMPNTRPVPDTKEQMEWLCKRIRETAYVHVLPYAAITVGQQGTELTDFAALKEAGAFAFTDDGVGVQSAGMMYEAMKRAAALDMAIVAHCEDNTLANRGVVHDGEFAHRYGLYGIPSVCESVHIARDVLLAEATGCHYHVCHISTKESVRVVRDAKRAGIRVTAEVTPHHLLLCDEDIPGPDANYKMNPPLRSKEDREALIEGLLDGTIDFIATDHAPHTEAEKQKGINAAPFGIVGLETAFPLLYTHLVETNILTLKQLIDLLTVKPAECFGLPLGKLAVGERADITIIDLETEEAIDPQTFVSRGKNTPFAGWKCKGWPVMTFVGGKLVWQKGRE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.201 kDa
Sequence
MYVLKNGQVLNESGELENKDVLIQNGKVNLIADSIEVTSGEEFDATGKLIAPGFIDVHVHLREPGGEHKETILTGTKAAARGGYTTICSMPNTKPVPDSKEVMNSLQAKIKETAEVRVLPYASITTSLGTDELVDFEALKEAGAFAFTDDGVGVQLAGTMYEAMKRAAALDMAIVAHCEDNSLIYGGVVHDGIFAEKEGLKGIPNIAESVQIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKRAGIRVTAEVSPHHLILDEEDIPGNDGNWKMNPPLRSKEDRAALLEGLLDGTIDFIATDHAPHAAEEKNVPMEQAAFGIVGLETAFPLLYTHFVKTNEWTLKQLIDWMTVKPAECFKLPYGKLEEGAVADIVVLDLEKEATIDPATFYSKGKNTPFVGETCIGWPVATFAEGELVYNEGENK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Listeria monocytogenes serotype 4b (strain CLIP80459)
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.144 kDa
Sequence
MYVLKNGQVLNASGELENKDVLIQNGKVNLIADSIEVTSGEEFDATGKLIAPGFIDVHVHLREPGGEHKETILTGTQAAARGGYTTICSMPNTKPVPDSKEVMESLQAKIKETAKVRVLPYASITTSLGTDELVDFEALKEAGAFAFTDDGVGVQLAGTMYEAMKRAAALDMAIVAHCEDNSLIYGGVVHDGIFAEKEGLKGIPNIAESVQIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKRAGIRVTAEVSPHHLILDEEAIPGNDGNWKMNPPLRSKEDRAALLEGLLDGTIDFIATDHAPHAAEEKNVPMEQAAFGIVGLETAFPLLYTHFVKTKEWTLKQLIDWMTVKPAECFKLPYGKLEEGSVADIVVLDLEKEANIDPATFYSKGKNTPFVGETCIGWPVATFSEGTLVYNEGEIK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2)
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.102 kDa
Sequence
MLIRFKGAHIVDPGNINEQKDLLVKDGLVHALLDPGAADPEPGIDTVDVTGMLLVPGLIDLHVHLREPGHEYKETIQTGLMAAAKGGFTAVCPMPNTSPVNDNAQVTRFILDRAKAAGLSRVYPVGAITLGLKGETLAEYGEMKQAGMVAITDDGRPVENARVMRRAMEYATGLGLPVMSHSEDLSLARDGAMNEGSFATRIGIKGIPNAAESIMVMREIAIAELTHARVHIAHVSCEESVDAIRHGKQRGVQVTCETAPHYFTLTDKAVGDYDTHAKMNPPLRSEADRLAVIKGLQDGTIDCIATDHAPHSPLEKAVEFDQAAFGIIGLETSLVLSLKLVQDELLSMETLVEKMSRNPARFLGLDNRLIPGNPADITVIDPDRVHVIDPETFVSKSRNTPFAGIEVKGEVLLTMVEGRIIYQREI
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.692 kDa
Sequence
MGIILGNGNVLNQAGELTPMEILVEKGRITAMGETLDRCGHDWIDCHGGMISAGLIDAHVHLREPGFEHKETIETGAKAAVQGGFTTVACMPNTRPSIDSVETVTYILDKASEAGMARVIPYGAITVRQLGKELTDFAGLKEAGIFALTDDGVGVQSTAMMKKAMQKAAELGIAIVAHCEDEDLLIPGAALHDGVVAARHGLPGIPSESESIHVGRDILLAEQTGVHYHVCHISAKESVRLVRDGKRAGVNVTCEVSPHHLLLCDEDIPDNLDTNWKMNPPLRSREDRAALIAGLKDGTIDMIATDHAPHTQEEKANGINRAPFGIVGLETAFPLLYTNLVQTGELTLKKLVELLTVKPAEAFKLPYGRLEVGAPADLTVMDLETEKTIDPSTFASKGINTPFAGWVCKGWPTLTLVDGKIVYQNV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Listeria monocytogenes serotype 4b (strain F2365)
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.129 kDa
Sequence
MYVLKNGQVLNASGELENKDVLIQNGKVNLIADSIEVTSGEEFDATGKLIAPGFIDVHVHLREPGGEHKETILTGTQAAARGGYTTICSMPNTKPVPDSKEVMESLQAKIKETAKVRVLPYASITTSLGTDELVDFEALKEAGAFAFTDDGVGVQLAGTMYEAMKRAAALDMAIVAHCEDNSLIYGGVVHDGIFAEKEGLKGIPNIAESVQIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKRAGIRVTAEVSPHHLILDEEAIPGNDGNWKMNPPLRSKEDRAALLEGLLDGTIDFIATDHAPHAAEEKNVPMEQAAFGIVGLETAFPLLYTHFVKTNEWTLKQLIDWMTVKPAECFKLPYGKLEEGSVADIVVLDLEKEANIDPATFYSKGKNTPFVGETCIGWPVATFSEGTLVYNEGEIK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Listeria monocytogenes serotype 4a (strain HCC23)
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.056 kDa
Sequence
MYVLKNGQVLNASGELENKDVLIQNGKVNLIADSIEVTSGEEFDATGKLIAPGFIDVHVHLREPGGEHKETILTGTQAAARGGYTTICSMPNTKPVPDSKEVMENLQAKIKETAEVRVLPYASITTSLGTDELVDFEALKEAGAFAFTDDGVGVQLAGTMYEAMKRAAALDMAIVAHCEDNSLIYGGVVHDGIFAEKEGLKGIPNIAESVQIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKRAGIRVTAEVSPHHLILDEEAIPGNDGNWKMNPPLRSKADRAALLEGLLDGTIDFIATDHAPHAAEEKNVPMEQAAFGIVGLETGFPLLYTHFVKTNEWTLKQLIDWMTVKPAECFKLPYGKLEEGSVADIVVLDLEKEATIDPATFYSKGKNTPFVGETCIGWPVATFAEGTLVYNEGEIK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.16 kDa
Sequence
MYVLKNGQVLNASGKLESKDVLIQNGKVNLIADSIEVTSGEEFDATGKLITPGFIDVHVHLREPGGEHKETILTGTKAAARGGYTTICSMPNTKPVPDSKEVMESIQAKIKETAKVRVLPYASITTSLGTDELVDFEALKEAGAFAFTDDGVGVQLAGTMYEAMKRAAALDMAIVAHCEDNSLIYGGVVHDGIFAEKEGLKGIPNIAESVQIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKRAGIRVTAEVSPHHLILDEEAIPGNDGNWKMNPPLRSKEDRAALLEGLLDGTIDFIATDHAPHAAEEKNVPMEQAAFGIVGLETAFPLLYTHFVKTNEWTLKQLIDWMTVKPAECFKLPYGKLEEGSVADIVVLDLEKEANIDPDTFYSKGKNTPFVGETCIGWPVATFAEGTLVYNEGEIK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.303 kDa
Sequence
MYVLKNGQILNESGELENKDVLIQNGKVNLIADSIEVTSGEEFDATGKLIAPGFIDVHVHLREPGGEHKETILTGTKAAARGGYTTICSMPNTKPVPDSKEVMERLQAKIKETAEVRVLPYASITTSLGTDELVDFEALKEAGAFAFTDDGVGVQLAGTMYEAMKRAAALDMAIVAHCEDNSLIYGGVVHDGIFAEREGLKGIPNIAESVQIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKRAGIRVTAEVSPHHLILDEEAIPGNDGQWKMNPPLRSKADRAALLEGLLDGTIDFIATDHAPHAAEEKNVPMEQAAFGIVGLETAFPLLYTHFVQTNEWTLKQLIDWMTVKPAECFKLPYGKLEEGTTADIVVLDLEKEATIDPDTFYSKGKNTPFVGETCIGWPVATFVEGTLVYKEGESK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
47.525 kDa
Sequence
MLALRVLLKGKILIGGRVREREVLAEDGWIVKIGKRLNEEADLTLELGKRELAVPAPIDLHVHCRDPHPDYPFGFKTETRRFLLGGVATVVDMPNTRPAPTTPETYYEKEELARENAEIEVIVAGGVRDSQCTKELVEAGAYVLGEVFLATSTDAPAVPWSTLPEIFRELSPDGPLTIFHPELDELVAERPARNLYEHLKNRPPEAETTAVGLLAGLKVRYPSRIHLSHVTLPESVKIAKGADITVDVTPHHLFFDVLRVDPEDPVFKVNPPLRGRHHRLGLLRAVRRGDVDVLASDHAPHILEDEFEDVPSGVTGGEIILPAALTLHRRFGLSLRDAVAMITCRPAKLLGRDDLGEVAVGKRARITVVRMREFVVRAEEFGEEDRKFPYDGMRMFGEPVKLIDGTKVYDLKESRREGKPVILEGE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.694 kDa
Sequence
MILIRNVRLVDARGERGPADVLIGEGRILSLEGGEAKQVVDGTGCFLAPGFLDLHAHLREPGEEVKEDLFSGLLAAVRGGYTDLVSMPNTKPPVDTPEAVRALKEKAKALGLARLHPAAALTEKQEGKTLTPAGLLREAGAVLLTDDGRTNEDAGVLAAGLLMAAPLGLPVAVHAEDAGLRRNGVMNDGPLADLLGLPGNPPEAEAARIARDLEVLRYALRRSPATPRLHVQHLSTKRGLELVREAKRAGLPVTAEATPHHLTLTEEALRTFDPLFKVAPPLRGEEDREALLEGLLDGTLDAIATDHAPHTLAEKEKDLLRAPFGIPSLEVAFPLLYTELHLKRGFPLQRLVELFTDGPRRVLGLPPLHLEEGAEASLVLLSPKERPVDPSAFASKARYSPWAGWVLGGWPVLTLVAGRIVHEALK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Syntrophus aciditrophicus (strain SB)
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.033 kDa
Sequence
MKILLKGGRVIDPAQNLDGQMDLLLENGKIAAIAEAVGSVPEDTRLLDLKGMILLPGLVDMHTHLREPGYEYKETIRSGSEAAAVGGFTSIACMPNTLPVNDNRTVTEYILKRAKECDTVHVYPVAAVSRNSEGKILAEFGDLKEAGAIAFSDDGKPVMNSILMRRALEYASSLDRIIISHCEDLNLSAGGLMNEGKISTELGLPGIPTLAEDVMVARDLLLAEFSGAALHIAHVSSAGAVRMIRDAKKRGVRVTAETTPHYFTLTDEAVTNFNTNTKVSPPLRSREDLQAVREGLRDGTLDAIVTDHAPHALTDKEVEFEYAANGISGLETALALSLTLVDDGLLTLSELVRKMSVNPAKILNIPKGTLRPGADADITVLNPGKTWVVDPSNWRSQGKNTPFFGWTLKGKVIMTLVQGRIVYQED
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Thermus aquaticus
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.93 kDa
Sequence
MILIRNVRLVDAMGERGPLDVLIGEGRILSLEGGEAKQVVDGTGCFLAPGFLDLHAHLREPGEEVKEDLFSGLLAAVRGGYTDLVSMPNTNPPVDTPEAVRALKEKAKALGLARLHPAAALTEKQEGKTLTPAGLLQEAGAVLLTDDGRTNEDAGVLAAGLLMAAPLGLPVAVHAEDAGLRRNGVMNDGPLADLLGLPGNPPEAEAARIARDLEVLRYALRRSPATPRLHVQHLSTKRGLELVREAKRAGLPVTAEATPHHLTLTEEALRTFDPLFKVAPPLRGEEDREALLEGLLDGTLDAIATDHAPHTQAEKEMDLLRAPFGIPSLEVAFPLLYTELHLKRGFPLRRLVELFTDGPRRVLGLPPLHLEEGTEASLVLLDPKERPVDPQGFASKARFSPWTGWRLGGWPVLTLVEGRIVHEALE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372)
Length
426 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.253 kDa
Sequence
MLIKGGHVVDPKTNTNGIMDILVEDGIITEIGKDIEISNGDIIYAEGKLVLPGLVDAHCHLRDPGFEYKEDIETGTMSAAMGGFTSIACMPNTDPVCDNKAVVKYIINKAKQDGYVNVYPIGAISKGQKGEELSEIGELKFAGAVAISDDGKPVKSSSLMKRALEYSSMFDIAVISHCEDLDLADGGVMNEGYWSTVMGLKGIPSAAEEIMVARDIILSEYTKVPIHIAHVSTELSVELIRNAKKRGVKVTCETCPHYFVLTDEACKDFNTLAKVNPPLRTRRDVEAVIEGLKDGTIDIIATDHAPHHADEKNVEFNLAANGMVGFETALPLAITYLVKPGHLTISQLVEKMCVNPSKLLGINKGTLETGRSADITIVDLNEEFVVDVNKFKSKSKNSPFHGFKLNGSVYYTLVNGNVVVREKVLL
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
47.382 kDa
Sequence
MLLKNCKILKNTKFEKVDILIRDNKIEKISENIDITDENIIDIKNRFVTAGFIDVHVHWREPGFSKKETVYTASRAAARGGFTTVMTMPNLNPVPDSVETLNKQLEIIKKDSVIRAIPYGAITKEEYGRELSDMEAIASNVFAFTDDGRGVQSANVMYEAMLMGAKLNKAIVAHCEDNSLIRGGAMHEGKRSAELGIKGIPSICESTQIVRDVLLAEAANCHYHVCHISAKESVRAVREGKKNGIKVTCEVTPHHLLSCDEDIKEDNGMWKMNPPLRSREDRNALIVGILDGTIDIIATDHAPHTMEEKIRGIEKSSFGIVGSETAFAQLYTKFVKTDIFSLEMLVKLMSENVAKIFDLPYGKLEENSFADIVVIDLEKEITINPNNFLSKGKNTPYINEKINGIPVLTISNGKIAYIDKEEINL
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Geobacter daltonii (strain DSM 22248 / JCM 15807 / FRC-32)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.169 kDa
Sequence
MNIFIKGGRVIDPSQNIDETLDLLVVAGRIKELGKGLKAPADAEVIDAAGLLVTPGLIDMHVHLRDPGLEYKEDVITGTMAAAAGGFTSVACMPNTKPVNDNKAITSYIVNKAKAEALVNVFPVGAITQGSKGENLAEMGELKEAGCVAVSDDGRPVVNAELMRRALEYAKGMGVMVIAHSEELALVGEGVMNEGFTATELGLKGIPWAAEDVAVARDVYLAEFTNSPIHIAHISTKGSVRIIRDAKARGVQVTCETAPHYFSLTDDAVRGYETNAKMNPPLREAEDVAAIKTGLADGTIDAIATDHAPHHLDEKDVEFNVALNGIIGLETSLPLSLKLVEEKVLDMKTLVEKMAVRPAQILGLDRGTLKTGAPADVTIIDPKAEWVVEAEKLASKSKNSPFLGRKMTGAAAYTIVDGKVVHKRD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.392 kDa
Sequence
MKTVIKNGTVYQNGRLIHADVLIEDQKIKVIGTNLTGDKEFDATGKLVAPGLVDVHVHYREPGQTYKEDIRTGSEAAARGGFTTVGAMPNVTPVPNTPELMEKMVKKNQEKGIVHIFQYGPITNDETTDIIPDYAALKKAGAFALSNDGHGVQTAQTMYLAMQKAKANNLIIATHAQDDSLFNHGIVNEGKKAEELNLPPVTELAETTQIARDLLLAQKTGVHYHICHVSTKTSVELVRMAKARGINVTCEVAPHHILLTDDDIPKDNGYYKMNPPLRNKEDQAALLVGLLDGTIDLIATDHAPHAKKEKQGGMKGAAFGITGSETAFSTLYTKFVKKDKVFTLEQLLSWLSDKPAEAFGLKDAGVLEPGKNADIAIFDIEHEATIEEKDYKSKGVNTPFTGQKVYGETVMTMVNGKVVYQRGTK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.291 kDa
Sequence
MQTVIKNGTVYQNGRLIHADVLIEDQKIKAIGTDLTGDKVIDATGKLVSPGLVDVHVHYRDPGQTYKEDIETGSKAAAHGGFTTVGAMPNVTPVPDTPDLMKKMVQENKQKGIVHIFQYGPITKNETTDELPDYAALKKAGAFALSNDGHGVQTAQTMYLAMQEAKKNDLIVAAHAQDDSLFNHGIVNEGEKAKELNLPPVTELAETTQIARDLLLAEKTGVHYHICHVSTKTSVELVRMAKACGINVTCEAAPHHLLLTEDDIPKDNGYYKMNPPLRSKEDQAALLVGLLDGTIDLIATDHAPHAKQEKQGGMQNAAFGITGSETAFSTLYTKFVKEDKVFTLEQLLSWLSDQPAKVFGLKKAGVLEPGCPADVAIFDLEHETELKEKNYQSKGINTPFTGQKIYGATVMTMVDGEVVYQRGEK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC BAA-365)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.301 kDa
Sequence
MQTVIKNGTVYQNGRLIHADVLIEDQKIKAIGTDLTGDKVIDATGKLVSPGLVDVHVHYRDPGQTYKEDIETGSKAAAHGGFTTVGAMPNVTPVPDTPDLMKKMVQENKQKGIVHIFQYGPITKNETTDELPDYAALKKAGAFALSNDGHGVQTAQTMYLAMQEAKKNDLIVAAHAQDDSLFNHGIVNEGEKAKELNLPPVTELAETTQIARDLLLAEKTGVHYHICHVSTKTSVELVRIAKACGINVTCEAAPHHLLLTEDDIPKDNGYYKMNPPLRSKEDQVALLVGLLDGTIDLIATDHAPHAKQEKQGGMQNAAFGITGSETAFSTLYTKFVKEDKVFTLEQLLSWLSDQPAKVFGLKKAGVLEPGCPADVAIFDLEHETELKEKNYQSKGINTPFTGQKIYGATVMTMVDGEVVYQRGEK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243 / JCM 1131 / NCIMB 11718 / AM63)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.019 kDa
Sequence
MATVIKNGTVYQNGRLIKADVLIEGKKIKAIGTDLDAEKIIDAQGMLVSPGLVDVHVHYRDPGQTYKEDIKTGSEAAARGGFTTVGAMPNVTPVPNTPELMKKMVEENKHKGVVHIFQYGPITNDETTDIIPDYAALKKAGAFALSNDGHGVQTAQTMYLAMQKAKENNLIIATHAQDDSLFNKGIVNEGVAAKKLDLPPVTELAETTQIARDLLLAQKTGVHYHICHVSTKTSVELVRLAKARGINVTCEVAPHHILLTDSDIPKDNGYFKMNPPLRNKEDQAALLVGLLDGTIDLIATDHAPHAKSEKQGGMKNAAFGITGSETAFSTLYTKFVKEEKVLSLEQLLALLSDKPAKVFGIENAGVLEPGKNADVAIFDIEHKNEIKEADFKSKGVNTPFTGQKVYGETVMTLVDGEVVYQRGTK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lactobacillus helveticus (strain DPC 4571)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.292 kDa
Sequence
MQTVIKNGTVYQNGRLIHADVLIEDQKIKAIGTDLTGDKVIDATGKLVSPGLVDVHVHYRDPGQTYKEDIETGSKAAAHGGFTTVGAMPNVTPVPDTPDLMKKMVQENKQKGIVHIFQYGPITKNETTDELPDYAALKKAGAFALSNDGHGVQTAQTMYLAMQEAKKNDLIVAAHAQDDSLFNHGIVNEGEKAKELNLPPVTELAETTQIARDLLLAEKTGVHYHICHVSTKTSVELVRMAKACGINVTCEAAPHHLLLTEDDIPKDNGYYKMNPPLRSKEDQAALLVGLLDGTIDLIATDHAPHAKQEKQGGMQNAAFGITGSETAFSTLYTKFVKEDKVFTLEQLLSWLSDQPAKVFGLKKAGVLEPGCPADVAIFDLEHETELKEKDYQSKGINTPFTGQKIYGATVMTMVDGEVVYQRGEK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.053 kDa
Sequence
MTTVIKNGTVYQNGHLIKADVLIDGQKIKAIGTDLEGEEIIDASGMIVSPGLVDVHVHYRDPGQTYKEDIKTGSQAAARGGFTTVGAMPNVTPVPNTAELMDKMVRENQKKGLVHILQYGPVTNDETTDIIPDYAALKKAGAFALSNDGHGVQSAQTMYLAMQKAKENNLIIAAHAQDDSLFNKGIVNEGIAAEKLDLPPVTELAETTQIARDLLLAQKTGVHYHICHVSTKTSVELVRLAKARGIKVTCEVAPHHILLTDSDIPEDNAYFKMNPPLRSKEDQVALLVGLLDGTIDLIATDHAPHAKAEKQGGMRGAAFGITGSETAFSTLYTRFVKEEKVFTLEQLLSLLTDKPATVFGIENAGLLAPGENADIAIFDIEHQREIKEDDFKSKGVNTPFTGHKVYGETVMTFVDGKVVYQRGTK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.344 kDa
Sequence
MKVLLKNARVIKSHQVQKTDVLVENDRITQIQPEINVEAEQIIDVKNQLLMPGLVDIHVHFRDPGQTDKEDVVSGSAAAVKGGFTTVLTMPNVDPVPDTPEKMTAMVKHNQTAGSLHIGQYGSITKKRTSEELVDFKALKEAGAVAFSNDGNGIQTAETMYQAMLQIKEVGLPLAAHVEDESLMQHGVMNQGTVAEKLGLPGISELAETAQLARDLEIARNTGAHYHVCHVSKARSVELIRRAQRDGVHVTAEVAPHHLFLDETMISMDNPMMKMNPPLRTLEDRQALLGGLLDGTIGMIATDHAPHTVKDKAGSMKTASFGITGLETAFPLLYTKLVKPGLCTVEQLVEWMSIQPAEIFNLKAAGQLEVGDVADLTVMNVEDEYEIKEADFASKGINSPFIGQKVYGQTQLTMVAGKIVYQREG
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pelobacter carbinolicus (strain DSM 2380 / NBRC 103641 / GraBd1)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.258 kDa
Sequence
MKILITNGRVLDPAHGIDEKFDVLIEDNRIAQVGTDIQTADAEKIDAAGCLVVPGLIDIHVHLRDPGFEYKEDIESGTRAAAAGGFTAVACMPNTSPVNDNKATTQYILHKAAQAGHAKVYPVGAITKGLKGESLAELGDMKQAGCVAVTDDGHPVSHGEIMRRALEYARSFDLPIVSHSEDLSLVGDGVMNDGFVATELGLRGIPWVAEVSAVARDVMLAEYTNARLHVAHVSTRGAVEIIRAAKARGARVTAETAPHYFTLTEDAVRGYDTHAKMNPPLRTSDDLEAIREGLADGTLSVIATDHAPHHPDEKNVEFNLALNGIIGLETALPLTLRLVEEGALSLSDAIACLTSGPAAALSLPGGTLEVGRPADVTIIDPEIKWTLDPQAGQSRSRNTPFGDWKLKGRAICTIVDGRITYRLSD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.174 kDa
Sequence
MAGWTVCVDFLYTGDKMLEDACAVISGERVERVHTGGFRGQPDLDLRGRSSLALPGVIDMHVHLRGLKLSYKEDEVSGTAAAASGCVTLVADMPNTQPPLRTPEALREKLASLEAGAKVDYTVYAGVPRSYGEAVEMASMGIAGFKIYPEDLVNLDSIKNVLEAAEEAGILVVLHPESHDMFAGPDYGWLRRVARPCHAEAASVELLHDAARECGCKPRVHITHASCPATVVESKKRGFTVDVTPHHLFLSEEEVAGPTHSWGKVNPPLRGVGERSLLTQLTIEGLVDAIASDHAPHSTWEKWMHPAIAPPGFPWLEWWPGFTAARLMRAVGLERFYSMVSQTPSTILGVGDRCLWDGCPATISVLQLERTRVYHKGYTKALYTPVLGMESFDCAATVIRGKIAYTAWEGVRGGATGVLATRVVH
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lysinibacillus sphaericus (strain C3-41)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.998 kDa
Sequence
MKKVLRNVQMLNEQGELQTVNIAMADGKITAIGQEVTVVNAEVIEGNGLIVAPGFVDVHTHLREPGFEHKETIATGSASAAKGGFTTICAMPNTKPVPDSVENMQLINGLIKESAVIRVLPYGSLTKDISGEVRTNVEELKAYGAVAFSDDGVGIQLASTMYEQMKDAAKHDMVVVAHCEDNSLIYDGVMHEGKRNKELDLPGIPSICESVQIARDVLLAEAAGARYHVCHVSTKESVRAVRDAKAAGIRVTAEVCPHHLLLEEMDIPSDDANWKMNPPLRGADDKDSLHAALLDGTIDCIATDHAPHTVEEKCCGMVGAPFGIVGFETAFPLLYTQFVETGKWTLKQLIDWMSVKAAEIFDLPYGTLAVGASADMILIDIQKEQTIDAEGFVSKGRNTPFNGWVAKGWPVLTIFEGNIVYQEAE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Geobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.694 kDa
Sequence
MNLLIKGGRVIDPSQGIDDTLDVVVENGLVKEIGKGLATSAGAETIDASGKYVVPGLIDMHVHLRDPGLEYKEDIISGTRAAVAGGFTSVCCMPNTKPAIDNKAIASYIINKAKTEGACNVFPVGTITQGMHGDRLAEMGELKESGCVAVSDDGKPVKNSELMRRALQYAAGIGIMVISHAEELELVGEGVMNEGFTSTELGLKGIPRVAEDIATAREIMLAEYVGAPIHIAHVSTKGAVRIIREAKGRGVKVTCETAPHYFTLTDDAVRGYNTNAKMNPPLREADDLAAIKAGLKDGTIDCIATDHAPHHLDEKDVEFNEAMNGIVGLETSLPLSLKLVDEGVLNLSQLIEKMSCKPSELLGLGRGSLKAGNVADITVIDPAKQWTVTESALASKSKNSPWLGATMAGAAACTVVGGKIVFSGR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.258 kDa
Sequence
MNLLIKGGRVIDPSQGIDEVLDILVENGAIKELGKGLAAPAGAGVVDAAGLIVTPGLIDMHVHLRDPGLEYKEDIVTGTRAAAAGGFTSVACMPNTKPVNDNKAVTSYIVAKAKAEGLVNVFPVGSITQGSKGDALAEMGDLKEAGCVAVSDDGRPVTSSELMRRALEYAKGMGIMVISHAEDLSLVGEGVMNEGFVSTELGLKGIPWAAEDAATARDVYLAEFTNSPLHIAHVSTMGSLRIIRNAKARGVKVTCETAPHYFSLTDDAVRGYNTNAKMNPPLRTADDLAAVKEALKDGTIDAIATDHAPHHLDEKDVEFNVALNGIIGLETSLPLSLKLVEEGVLTLPALVEKMACNPAAILGIDRGTLRQGAVADITVIDPAAVWTVEAGALASKSKNSPFLGWEMKGAAAYTIVGGTVVHSRG
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Geobacter sp. (strain M21)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.478 kDa
Sequence
MNLLIKGGRVIDPSQGIDANLDVLIADGVVLELGQGLAAPEGTPAIDAGGLIVTPGLIDMHVHLRDPGLEYKEDIATGSRSAAAGGFTSVACMPNTSPVIDSKAIASYIINKAKSEALVNVFPIGCITKGGKGESLAEMGELKEAGCVGVSDDGKPVCNSELMRRALEYAKGIGITVISHSEDLALVGEGVMNEGFVSTELGLKGIPWAAEDIAVAREVYLAEFAGAPVHIAHISTVGSARIVRNAKARGVKVTCETAPHYFTLTDEAVRGYDTNAKMNPPLRSAADIEAMKAGLADGTIDAIATDHAPHHPDEKDVEFNVALNGIVGLETSLPLSLKLVEEGRLDLNQLVSLMSCNPAKILGLDRGTLKVGAVGDVTVIDPAKEWQVEAAKLESKSKNSPFLGWKMKGRAVYTVVKGQVVYQAG
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Geobacter uraniireducens (strain Rf4)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.938 kDa
Sequence
MNLLIKGGRVVDPSQNIDDTMDLLVEDGRIKEIGKGLKAPAGAEIIDAAGLLVTPGLIDMHVHLRDPGLEYKEDIVTGTRAAAAGGFTSVACMPNTKPVNDNKAITSYIVNKAAKEALVNVFPVGSITQGSKGESLAEMGELKESGCVAVSDDGRPVVNGELMRRALEYAKGMGIMVISHSEELALVGEGVMNEGFTATELGLKGIPWAAEDVAVARDVYLAEFTDSPLHIAHISTSGSVRIIRNAKARGVKVTCETAPHYFSLTDDAVRGYNTNAKMNPPLREAADVAAIKAGLADGTIDAIATDHAPHHLDEKDLEFNLALNGIVGLETSLPLSLQLVEEGVVDLKVLLEKMTCNPAKILGIDRGTLKVGAAADITVIDPDREWLVAAEKLASKSKNSPFIGRKMKGAAVYTVVGGKVVYKID
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.795 kDa
Sequence
MKLIKNGKILKNGILKDTEILIDGKRIKQISSKINASSSNIEVIDAKGNLIAPGFVDVHVHLREPGGEHKETIESGTKAAARGGFTTVCPMPNTRPVPDTVEHVRELRQRISETAQVRVLPYAAITKRQAGTELVDFEKLALEGVFAFTDDGVGVQTASMMYAAMKQAAKVKKPIVAHCEDNSLIYGGAMHKGKRSEELGIPGIPNIAESVQIARDVLLAEATGCHYHVCHVSTKESVRVIRDAKKAGIHVTAEVTPHHLLLTENDVPGDDSNYKMNPPLRSNEDREALLEGLLDGTIDCIATDHAPHAKEEKEQPMTKAPFGIVGSETAFPLLYTHFVRRGNWSLQQLVDYFTIKPATIFNLNYGKLHKDSYADLTIIDLNTEKEIKSEDFLSKADNTPFIGEKVYGNPTLTMLKGEVVFEEEK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Staphylococcus epidermidis (strain ATCC 12228)
Length
425 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.766 kDa
Sequence
MKLIKNGKILKNGILKDTEILIDGKRIKQISSKINASSSNIEVIDAKGNLIAPGFVDVHVHLREPGGEHKETIESGTKAAARGGFTTVCPMPNTRPVPDTVEHVRELRQRISETAQVRVLPYAAITKRQAGTELVDFEKLALEGVFAFTDDGVGVQTASMMYAAMKQAVKVKKPIVAHCEDNSLIYGGAMHKGKRSEELGIPGIPNIAESVQIARDVLLAEATGCHYHVCHVSTKESVRVIRDAKKAGIHVTAEVTPHHLLLTENDVPGDDSNYKMNPPLRSNEDREALLEGLLDGTIDCIATDHAPHAKEEKAQPMTKAPFGIVGSETAFPLLYTHFVRRGNWSLQQLVDYFTIKPATIFNLNYGKLHKDSYADLTIIDLNTEKEIKSEDFLSKADNTPFIGEKVYGNPTLTMLKGEVVFEEEK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Geobacter bemidjiensis (strain Bem / ATCC BAA-1014 / DSM 16622)
Length
424 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.44 kDa
Sequence
MNLLIKGGRVIDPSQGIDANLDVLIADGVVLELGQGLAAPEGTPAIDASGLIVTPGLIDMHVHLRDPGLEYKEDIATGSRSAAAGGFTSVACMPNTSPVIDSKAIASYIINKAKSEALVNVFPIGCITKGGKGESLAEMGELKEAGCVAVSDDGKPVCNSELMRRALEYAKGIGIAVISHSEDLALVGEGVMNEGFVSTELGLKGIPWAAEDIAVAREVYLAEFAGAPVHIAHISTVGSARIIRNAKARGVKVTCETAPHYFTLTDEAVRGYETNAKMNPPLRSAADVEAMKAGLADGTIDAIATDHAPHHPDEKDVEFNVALNGIVGLETSLSLSLKLVEEGRLDLNQLVSLMSCTPAKILGLDRGTLKVGAVGDVTIIDPAKEWQVEAAKLESKSKNSPFLGWKMKGRAVYTVVKGQVVYQA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pelobacter propionicus (strain DSM 2379 / NBRC 103807 / OttBd1)
Length
424 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.088 kDa
Sequence
MNLLIQNGRVIDPSQGLDEELDLLVENGLVREMGRGLTAPAGVEIVDAAGCCVVPGLVDMHVHLREPGLEYKEDIESGSRAAVAGGFTSIACMPNTKPVIDNKALARYVIARGREAGLCNVFPVGCLTAGSKGERLAEMGELKEAGCVAVSDDGRPVVNAELMRRALEYARGMQIPVISHAEDLSLVGEGVMNEGFTSTELGLKGIPRVAEDIAIARDVMLAEYTNSPIHIAHVSTSGAVRIIRNAKLRGVRVTCETAPHYFTLTDDAVRGYNTNAKMNPPLREADDVAAIRAGLSDGTIDVIATDHAPHHLDEKDVEFNVAANGIIGLETSLPLSLALVEQGVLTMSQLVERMSCCPSLILGLERGTLAKGAVADITLIDPTLPWVVEADKLASKSTNTPWMGQEMKGAAVATIVAGRVVYRR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
Length
424 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.713 kDa
Sequence
MNLLIQGGRVIDPSQGIDEVLDILVENGAVKELGKGVKAPSGTETIDASGLIVTPGLIDMHVHLRDPGHEYKEDIVSGTKAAAAGGFTSVACMPNTKPVNDNKAVTSYIIAKAKAEGSVNVFPVGSITQGSKGELLSEMGELKESGCVAVSDDGHPVTNSELMRRALEYAKGMGIMVISHAEDLSLVGAGVMNEGFVSTELGLKGIPWAAEDAATARDVYLAEFTDSPLHIAHVSTKGSLRIIRNAKARGVKVTCETAPHYFSLTDDAVRGYDTNAKMNPPLRTADDVTAVKEALKDGTIDAIATDHAPHHIDEKDLEFNEALNGIVGLETSLTLSLRLVEEGVLTLPVLVDKMACNPAKILGIDRGTLKPGSVADITVIDPKATWTVDADKLASKSKNSPFLGWEVKGAAAFTIVGGKVVYKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Length
424 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.528 kDa
Sequence
MIIIKNGYVIDPLTKREGKFDILIDGENVVRISQDIGIDDDIEVIDAEDCIVSPGFIDIHSHFRDPGFTEKEDIITGARAAARGGYTTVICMANTNPVVDNVETLRYIVDKAKTAKIEVLQVGTITKGMQGVELVDMEALKEAGAVGFSDDGKPIMDSRLVLEAMQKARELDVPLSFHEEDPKLVYESGINGGKVAEKLNMMGALEEAETVLTARDAALAVSSGAKTNIQHISSKISLGIIKLAKEMGANIIAEATPQHFSITEEEILNCGTNAKVNPPLRREDDRKAIVAALKDDTIQVIATDHAPHTKDEKAREFKEAPSGMIGLETALSLAVTNLVKTGDLTYRDMISKLTINPARFYNLDRGYIKEGHRADIVIFDPDEKYTVKEEEFQSKASNSPFIGKELFGKVKTTIYNGKIVYEDK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Staphylococcus aureus (strain COL)
Length
424 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.372 kDa
Sequence
MKLIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGVDIIDAKGHFVSPGFVDVHVHLREPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLIDDNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVNKAIVAHCEDNSLIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPCETFNLEYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKFEGDK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Length
424 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.372 kDa
Sequence
MKLIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGVDIIDAKGHFVSPGFVDVHVHLREPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLIDDNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVNKAIVAHCEDNSLIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPCETFNLEYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKFEGDK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Staphylococcus aureus (strain N315)
Length
424 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.372 kDa
Sequence
MKLIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGVDIIDAKGHFVSPGFVDVHVHLREPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLIDDNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVNKAIVAHCEDNSLIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPCETFNLEYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKFEGDK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Staphylococcus aureus (strain MRSA252)
Length
424 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.386 kDa
Sequence
MKLIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGIDIIDAKGHFVSPGFVDVHVHLREPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLIDDNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVNKAIVAHCEDNSLIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPCETFNLEYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKFEGDK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Staphylococcus aureus (strain MSSA476)
Length
424 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.372 kDa
Sequence
MKLIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGVDIIDAKGHFVSPGFVDVHVHLREPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLIDDNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVNKAIVAHCEDNSLIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPCETFNLEYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKFEGDK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Staphylococcus aureus (strain MW2)
Length
424 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.372 kDa
Sequence
MKLIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGVDIIDAKGHFVSPGFVDVHVHLREPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLIDDNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVNKAIVAHCEDNSLIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPCETFNLEYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKFEGDK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Lactococcus lactis subsp. lactis (strain IL1403)
Length
423 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.676 kDa
Sequence
MTLLIKNGRLVDPKSNRDEVLDILIENDKIVKIGLNLSVENAEIVDARGLVVAPGLIDVHVHFREPGQTHKETIHSGAKSAAAGGFTRVVMMANTKPILSTPKVLTETLEIADKEDIKIDAVGSITQDFDGEHLTDFDELIKAGAIGFSDDGIPLTDAGVLRKALQKAKLTDSLISIHEEDPNLIGTLGVNDGEVAHKCGFTGAPTVSEYSMMARDSMIAYETGARLHIQHLSAGESVEVVRFAKNLGAKITAEVTPQHFSITEQMIFEQGTNAKLNPPLRSTTDIGKIIEGLKDGTIDVIATDHAPHTREEKNVSLDKAPSGMIGLETSLQLGLTNLVAKGHLTLSELLTKMTVNPAKLYNFDAGYLAENGPADLVIFDAENDYQVGETFDSKATNSPFIKQKVQGQVKYTICDGKIVYQAK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
423 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
48.104 kDa
Sequence
MLLKNCRIIKDNKIIEGDILIDENGRIKKIAKDIKVDDEIIDIKNSLVIPGVIDAHVHFRWGEEKKEDFLSGSLAGINGGVCFAIDMPNNKPPITTKELFYKKLEDCKKDSKINVFLNFGVTENNYLGTVEDAKAYKIFMVKSVGDLFIEDYSKLKDILNQNKLFCIHAEHKDVINENLKKYQLNSWIDHCKIRDEKSEVEAVKEVIKNLKIIDRQSNKKPHVHFCHISTKEALYLIKKVRQELKNIKITVEVTPHHIYLNKDMAEELKGFGKFNPPLREKDDNIALIKGIVNKDVDIIASDHAPHLLEDKLKNVKNCPSGIPGIETIVPLTLNLVNKGLISLFDAIRVLSKNPAKIFNINNKIEEGNLANLTIIDLKKEGKINAELFKSKAKFSPFDGWEVKGFPIYTVINGTLYEAYGCKC
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Sulfurihydrogenibium sp. (strain YO3AOP1)
Length
423 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.638 kDa
Sequence
MILIKNGHIVDPQNNLNDKFDILIEKGEIKKIEKNIQPFAGCEVIDAEGKIITPSFTDIHVHFRDPGQTYKEDIESGSKAAVAGGYTTVVCMPNTIPAIDDVPIVRYIIEKGEEIGLCRVLPSAAITKGRKGKELTEMALLKDAGAVYFTDDGAPVMDSFIMRKAMEYAGSLGTFVADHCEDLNLSQNGVAHEGEIAAALGLPPLPPEAEDTMVARDCILSIQTGMPVHICHISTKLSVEIVAWAKAMGAKVTAEVTPHHLYLTDEEFLDFSCIAKVSPPLRTHEDIEATRWALASGIIDFVATDHAPHAHYEKMQELQACPPGMLGLQFALPIVLELVKKDYFDLNRMVEVMSIQPAKKIGLKPPQIKEGEIAELTIFDPFETWEVNKETILSKSKNTPLLGRKLTGKVKYTFFKGKIVYRD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Uncultured termite group 1 bacterium phylotype Rs-D17
Length
422 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.205 kDa
Sequence
MRLQIKDIKIIDPLQNRDLIGDIFVENGRIVSKFLGDADKVVDGRGKIAVPGLIDIHSHLREPGEERKETIYTGTRSAAKGGITTVFCMPNTKPVIDNAPTVEFVLLKAQKEGLVNVLPIGCATKGSHGVEISEIGVLKKAGIVAVSDDGLPIANSQIMRRTLEYTKMFKLPVISHGEDKELSKNGVMNEGKNSMILGLRGIPKQAEEVIISRDIMLAELTEGYLHIAHVSTAGSVELIRQAKKKSIKVTAETCPHYFTLTDDIVKGYNTNTKMNPPLRRQEDVDAIKQGLADGTIDCIATDHAPHMEEEKNREFDLAPFGIIGFETILSLILNELVDSGVLSLSKALSKMTSNPAKIFNLEGRGTLKEGNIADITIIDMKYSYEFKKENIVSKSKNSPFIGRKFKGGAVMTIVGGNIVWQV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
Length
422 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.817 kDa
Sequence
MRVIRDAVLADGRVRDIRLDGERIDAVGTALDGELFVDANADYRVLPGMIDAHVHFRQPGFEHKETWASGSRSAAAGGVTTVVDQPNTAPPTVTGDAVDEKAAHAAADSVVDWGVNGGVTGEWDPASLFDRSLFALGEVFLADSTGDMGIDAALFRDACQRAASEDVVVTVHAEDADRFDTAAKSRSDADAWSAYRTPEAEAAAVERAVEVGTEAGATIHIAHTSTPEGVDAAAAGGATCEATPHHLFLSRDDLDDLGTFGRMNPPLRSDPRREALFERLADGRIDVVATDHAPHTRAEKAADIWDAPSGVPGVETALPLLLGAAHRGELSYERVRDVTAANPADVFGLERKGHIAAGRDADLVLVDPDDAREIHGDDLHSNCEWTPFEGHVGVFPAMTLVRGTTVWDGDTVSAFDGRNVRQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Streptococcus thermophilus (strain CNRZ 1066)
Length
422 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.949 kDa
Sequence
MLLIKNGRVVDPKSGLDTQADVLVDGKKVVKIAENIDAGDAQVIDATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTNPTISDKETLKEVLTSAAKENIHIKSVATITKNFDGENITDFKGLLEAGAVGFSDDGIPLTNAGIVKKAMELAKENNTFISLHEEDPDLNGVLGFNENIAKKEFHICGATGVAEYSMIARDVMVAYDTQAHVHIQHLSKAESVKVVEFAQKLGAQVTAEVAPQHFSKTEDLLLSKGANAKMNPPLRLESDRQAVIEGLKSGVISVIATDHAPHHADEKNVADVTKAPSGMTGLETSLSLGLTYLVEAGHLSLTELLKLMTSNPSDLYGFDAGYLAENGPADLVIFADKEKRQVTADFKSKAANSPFVGEELTGSVKYTICDGEIVYQV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
Length
422 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.949 kDa
Sequence
MLLIKNGRVVDPKSGLDTQADVLVDGKKVVKIAENIDAGDAQVIDATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTNPTISDKETLKEVLTSAAKENIHIKSVATITKNFDGENITDFKGLLEAGAVGFSDDGIPLTNAGIVKKAMELAKENNTFISLHEEDPDLNGVLGFNENIAKKEFHICGATGVAEYSMIARDVMVAYDTQAHVHIQHLSKAESVKVVEFAQKLGAQVTAEVAPQHFSKTEDLLLSKGANAKMNPPLRLESDRQAVIEGLKSGVISVIATDHAPHHADEKNVADVTKAPSGMTGLETSLSLGLTYLVEAGHLSLTELLKLMTSNPSDLYGFDAGYLAENGPADLVIFADKEKRQVTADFKSKAANSPFVGEELTGSVKYTICDGEIVYQV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Aquifex aeolicus (strain VF5)
Length
422 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.38 kDa
Sequence
MLKLIVKNGYVIDPSQNLEGEFDILVENGKIKKIDKNILVPEAEIIDAKGLIVCPGFIDIHVHLRDPGQTYKEDIESGSRCAVAGGFTTIVCMPNTNPPIDNTTVVNYILQKSKSVGLCRVLPTGTITKGRKGKEIADFYSLKEAGCVAFTDDGSPVMDSSVMRKALELASQLGVPIMDHCEDDKLAYGVINEGEVSALLGLSSRAPEAEEIQIARDGILAQRTGGHVHIQHVSTKLSLEIIEFFKEKGVKITCEVNPNHLLFTEREVLNSGANARVNPPLRKKEDRLALIEGVKRGIIDCFATDHAPHQTFEKELVEFAMPGIIGLQTALPSALELYRKGIISLKKLIEMFTINPARIIGVDLGTLKLGSPADITIFDPNKEWILNEETNLSKSRNTPLWGKVLKGKVIYTIKDGKMVYKD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Streptococcus pyogenes serotype M1
Length
422 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.291 kDa
Sequence
MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVETLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLKEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLIAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKTVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFASKASNSPFIGNKLKGVVKYTIADGEVVYPN
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
Length
422 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.248 kDa
Sequence
MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVETLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLKEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFASKASNSPFIGNKLKGVVKYTIADGEVVYPN
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
Length
422 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.248 kDa
Sequence
MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVETLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLKEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFASKASNSPFIGNKLKGVVKYTIADGEVVYPN
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Streptococcus pyogenes serotype M18 (strain MGAS8232)
Length
422 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.248 kDa
Sequence
MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVETLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLKEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFASKASNSPFIGNKLKGVVKYTIADGEVVYPN
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Length
422 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.355 kDa
Sequence
MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETIDATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVETLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIVKEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMIAYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMNPPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLSLTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFASKAANSPFIGETLKGQVKYTICKGQIVYQA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Streptococcus pyogenes serotype M3 (strain SSI-1)
Length
422 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.248 kDa
Sequence
MILIKNGRVMDPKSQRDQVADVLIDGKQIVKIASAIECQEAQVIDASGLIVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDVETLQEVLASAAKEKIHIYTNASVTQAFNGKDVTDFKALLEAGAVSFSDDGIPLESSKVLKEAFDLANANQTFISLHEEDPQLNGVLGFNEGIAEEHFHFCGATGVAEYSMIARDVMIAYDRQAHVHIQHLSKAESVQVVAFAQQLGAKVTAEVSPQHFSTTEDLLLTAGTSAKMNPPLRTQRDRLAVIEGLKSGVITVIATDHAPHHKDEKAVDDMTKAPSGMTGLETSLSLGLTHLVEPGHLTLMSLLEKMTLNPALLYGFDAGYLAENGPADLVIFADKQERLITENFASKASNSPFIGNKLKGVVKYTIADGEVVYPN
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Length
422 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.325 kDa
Sequence
MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETIDATGHVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVETLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIVKEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMIAYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMNPPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLGLTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFASKAANSPFIGETLKGQVKYTICKGQIVYQA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Desulfotalea psychrophila (strain LSv54 / DSM 12343)
Length
421 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.919 kDa
Sequence
MIIILKGGRVIDPRNRRDEDADIWMEDGQIIAPQETVPEDAKIYDLAGKWVVPGLIDMHVHLRDPGEEYKESIVTGTDAAAAGGFTAVACMPNTDPVNDTGSVTRYILEKSEGAAARVYPVGALSEGLKGESLAEYADMKHAGAVALTDDGNPVVSSQLMRRAMEYAKSHDMLVISHSEEPTLSKRGCMNEGLVATRLGLKGIPAVAESIMVQREIALAGLTGARLHIAHVSCIESLAAIRDAKKRGLPVTAETAPHYFSLTDDAVIGYDTHAKMNPPLRTEEHRQAIRQALADGTLDVIATDHAPHSIVEKEVTFEYAANGIVGLETSLGLSLALVRDGVLTPSRLVELMSSVPAQILSVAGGELGVGAIADVTVIDPELEHTFLIAEGRSRGANSPFDGWKLKGAATLTFVAGEESYCR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Peptoclostridium difficile (strain 630)
Length
421 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.976 kDa
Sequence
MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKIIDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNEDTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNLIMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCMLALKTGAKVDIQHISSGVSVDMVRFAKYLGATVVAEASPHHFTLTEEDVLEFGTNAKMNPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALGITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVSKADNSPFKGKSLYGKVNYTICNGEIVYNA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Length
417 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
47.226 kDa
Sequence
MTQVDLVVVGKFLFKEKIIDGSIGIEDDKIAKFSLRELKGDKKIKVEKGKIILPGLIDVHVHLRDFNESYKETIASGTKAAIHGGITTVFDMPNTKPPIMDEKTLKLRELIFKKKSYSDYALGFLIAGNEPAKADFYKIFMGASTGGIYSKNFEEDYKKAPDIVSVHAEEYELINRYPERPPIVEVVAIKKALQASKKMKKPLHICHVSTKDGLKEILKANIPWVSFEVTPHHLFLTRRDYERSKLLKVYPPLRDEEDRRYLWENLKSIPIIASDHAPHTLEDKEAGAAGLPGLETEVALLLDAVNKGMITIWDIVAKMSINPARIFKIKNKGWEEGKDADLIVVDMKKEWTIKAENFYTKANWTPYEGWKVKGKVIMTILRGEVVMEDDEIIGKPRGERIVKEGNAQGNLGSSQEH
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Length
416 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.917 kDa
Sequence
MTITITNIKRVGSEQTESLTIENGLIKGWNLPAEGEIFDGQGGTLAPALIELHAHLREPGQTEKEDLASGLAAASAGGYGTVVCMPNTRPVIDDPALVRSLIEKARGLGFARLRPAAAVTKGEKGEQLTEMSYLKEAGAVMFTDDGLTNENARVLRLGMEYAKSLGMVISVHAEDDALRAGGVMNEGPVSESLGLPGNPAAAAAARVARDMEIVALTGARLHVQHLSTARELDIVRDAKRRGLPVTCEVCPHHLDLTDESLRTFDAMYKVAPPLRTRADADYLLEGLLDGSVDCIATDHAPHTRAEKERDLLDAPSGIAYIEIAFPIMWTRFGERLGLEKLIDLMTAGPARVMGWPEPSLEAGAPADMVVLDLETEREVNPAEFKSKAKFTPWQGQKLRGFPLLTVVDGKVAYRRE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Length
415 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.139 kDa
Sequence
MDRAFCGNFYYNGKFDYLEVTVKDGVIESIKKDAGNIARSYLPGAVLPAATDIHVHFRTPGETDKEDFSTGSLSAIFGGTTLVMDMPNNIIPIKDYNAFSDKLGVINGTSYSDFALYSMETGSNSLIVDSRSIGLKVYLGGSTNAAGTMAIPDQEAEMINEKGFTVIFHGELEECLRKHQSETKNLREHNLSRPIECELAAAGYVGSLNLKSKIMAHVSSPEVSGDFLREVTPHHLLLNDEMPLGSIGKVNPPLRDRNTQERLLYAYISGQFDILSSDHAPHTEKDKAEFEYAKSGIIGVETRIPLMLALVKKKILFLDVLYKTGIERPPSIFGIRKGKIEVGYDADFMCVDFTNEKKVNEDRLHSKLPRSPFNGMDAIFPSHVVMRGEVVIDNYEEISDPLGRFVPKGYYDQKL
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Length
414 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.985 kDa
Sequence
MEVVLEGKFLLDKRTIEGYIGIEDGKISKISLREIKGDHKIKVDKGKVILPGLIDVHVHLRDFEESYKESIESGTKAAVHGGITVVFDMPNTKPPIMDEKTLKLREHLFKRKSYADYALGFLLAGNKPVEADFYKIFMGASTGGIYSKNFEEDYIRALDIVSIHAEDYEIIQKYPERPPIAEIRAIERVIEAVKTHKKPAHICHISTAKGLKLLLDSRLEMLSFEVTPHHLFLTRSDYDKNPLLKVYPPLRSEEDRIALWKNIDKVPVIASDHAPHTLEDKEAGAAGLPGLETEVPLLLDAVNKGLITLQDIVEKMHINPIKIFGIENKGFEKGKDADFTIVDMKREWTIRADNLYTKAGWTPYEGWRVKGKVIMTIIRGEVVMEEDEIIGKPRGERIVKKGKHRRNLGSSEEH
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Length
414 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
46.244 kDa
Sequence
MCMDRAICGNFYYGGKFDYLEVIVSDGKIAGIKKDAGNVPKTNYDGAILPAATDIHVHFRTPGETEKEDFGSGSLSAIYGGTTYVMDMPNNRFPITDYNAFGDKLGSIDSTSFADFSLYSMETGKNAMLLDRRSIGLKVYLGGSTNSTGTEVIEEGDIRKINEMNYPVVFHGESERCLKTHQMEEKNLRDHNLARPIDCEIEAAKYVSGLDIKTKIMAHVSSPDVTGNFLREVTPHHLLLNDEMPLGSFGKVNPPLRDSRTQKRLLDDYISGKFDILSSDHAPHTEDDKREFEFAKSGIIGVETRVPLFLALAQKKIVPLDVLYRTAIENPPSIFGIKKGKIEIGYDADFMVIDFTSMKRINDNRLHSKFPVSPFNGMDAIFPSHVIMRGNVVIDRYEDISDPMGVFIPKPQKE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Length
409 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.471 kDa
Sequence
MHELVLSGRFVLNGEIVGGSIGIDNGLITEISRRDIKGEEVIAFKSEIILPGLIDTHVHLRDFEQKEKETVESGTKAALHGGITAVFDMPNTKPPIMDVKTFEKRLSILEKHAYSDYAASFLLAGNCGEASRARADFYKIFMGASTGGIFSENFESDYSCAPGIVSVHAEDPETIRENPERPPEAEIRAIKKALTAAEKLRKPLNVCHVSTVGGIEAIIKKNLPWVSFEVTPHHLFLTSKDFERNPLLKVYPPLRSEEHRKALWENFSRIPIIASDHAPHTIEDKEAGAAGIPGLETEVALLLDAANRGLITVFDIVEKMHDNPVRFFGIKGRDFSLGNEATFTIIDPKKEWKVKPEEFYTKAKWSPWEGKKLKGKVVMTVIRGMVVMEGDEIIEEPKGVRLDVQGGNH
Protein
Dihydroorotase: pyrC

Gene
PYRC
Protein
Dihydroorotase, mitochondrial
Organism
Oryza sativa subsp. japonica
Length
406 amino acids
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
44.871 kDa
Sequence
MQTAATSTFFANPHVKHLPGPFLRPSPHYGALVHLPSFRNKTPISIAMAASPSPPPLQELTITRPDDWHLHLREGDVLAAVLPHSAMHFGRAIVMPNLKPPVTTTARALEYREEILRALPPGSNFVPLMTLYLTDNTSPEEIKLAKKSGVVFAVKLYPSGATTNSQDGVTDIFGKCLPVLEEMARQEMPLLVHGEVTDQHVDTFDREKVFIEKILAPLVQRLPQLKIVMEHITTMDAVNFVESCKEGHVAATVTPQHLLLNRNALFQGGLQPHNYCLPVLKRETHRQAIVSAVTSGSKQYFLGTDSAPHDKRRKECSCGCAGIYSAPVALSLYAKVFEQAGALDKLEAFTSFNGPDFYGLPRNTSKIVLRKSAWKVPDTYSYSSGEIVPMFTGNTLEWLPSDQLEE
Protein
Dihydroorotase, mitochondrial: PYRC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pyrococcus abyssi (strain GE5 / Orsay)
Length
404 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.881 kDa
Sequence
MELVLVGKFLYNGRIIDGSIGVKDGKITKFSLRELKGDNKIKVEKGKIILPGLIDVHVHLRDFNETHKETIETGTKAAVHGGITTVFDMPNTKPPVMDEKTLKMREFLFKKKSYADYALGFLLAGNEPVKADFYKIFMGASTGGIYSKNFEEDYAKALDITSVHAEDYELISKYPERPPIVEISAIKKALNAARKVKKPLHICHVSTREGLKEILEANIPWVSFEVTPHHLFLTRKDYEKSKLLKVYPPLRDESDRRYLWEKLDNVPIIASDHAPHTLEDKERGAAGLPGLETEVALLLDAVNRGMLELWDVVEKMSLNPARIFRIKNKGWGEGKDADFAIVDMKKEWTIKAEEFYTKAGWTPYEGWKVRGKVIMTILRGEIVMEDDEVIGKPRGERIVKEGDD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Length
403 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
45.559 kDa
Sequence
MIRGKVFYKGEFVEAGIEVENGRIKRIGKLVEGKEVKGVILPAGIDVHVHLRDFAEKRKETIETGTLSALHGGICLVVDQPNTKPPVDDAETYFRRMGKAEKSVYVDYALNLALTNSNHGKIGSIMRKISERYFVPAVGEVFIQHDSEDLQIDYETLSSVYKRFEGVVFTIHAEDPAYVARGSPNFVFRRREAEVLAVERLVELGKFHFCHISTKDSAKEILNSNSTYEVTPHHMLLSVEDYGRLGNLVNVNPPLREREDVEWLFRNFHRIDVLASDHAPHTLEDKEAGASGFPGVETMYPLFVNLASKGYISFKTLVEKIASNPARIFGFKGYGEIEVGNYANFAVFDLKKVDEIRAERLHSKCGWTPFEGFEAVFPDKVYLRGKELLENEMKAGNVLKKRV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Clostridium botulinum (strain Alaska E43 / Type E3)
Length
398 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.227 kDa
Sequence
MELLIKNARIIDAIQDFKGDIYIKDGVINEIAKEINKDNVEVLNCEEKILMPAFIDTHAHFRDPGLTWKEDLESGSKAALKGGYTGVCLMANTKPICSSKEVVQYVRDKSKELDLIDIHQCISVTQNFDGKTLDHLNEFKDDNKVKAISDDGVGVSNSNIMLEAMKIAKENNWVLMSHAESPEFSKSDMRIAENMMTIRDVELAKLSGAHVHMCHVSTKEALKCIIAAKNEGANITLEVTPHHIGLTKEINDYRVNPPIREKEDVEEIIKAIKMGNIDTIGTDHAPHTLEEKSKGSPGMVGLETAFPICYTKLVRENGVSLNELSKLMSLNPAKLLGMNKGKISIGVDADLVLIDIDKKIKVDSNEFISKGRNTPFEGMEYYGEVLATIKSGKIKYKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Clostridium botulinum (strain Eklund 17B / Type B)
Length
398 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.23 kDa
Sequence
MELLIKNARIIDAIQDFKGDIYIKDGVINEIAQEIKKDNVEVLNCEEKILMPAFIDTHAHFRDPGLTCKEDLESGSKAALRGGYTGVCLMANTKPICSSKEVVQYVRDKSKELDLIDIHQCISVTQNFDGKTLDHLNEFKDDNEVKAISDDGVGVSNSNIMLEAMKIAKENNWVLMSHAESPEFSKSDMRIAENMMTIRDVELAKLSGAHVHMCHVSTKEALKCIIAAKDEGANITLEVTPHHIGLTKEINDYRVNPPIREKEDVEEIIKAIKMGNVDTIGTDHAPHTLEEKSKGSPGMVGLETAFPICYTKLVRENGVSLNELSKLMSLNPARLLGMNKGRISIGVEADLVLIDIDKKIKVDSNEFVSKGRNTPFEGMEYYGEVLATIKSGKIKYKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Length
390 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.333 kDa
Sequence
MMILWIMGKAYLSKEIRDVCINFDRRIKEIKSICKPDIALPKGTLILPGAIDLHTHIRGLKLAYKEDVVSGTSEASYGGITLIGDMPNSVPFVNTMETITAKLREFEYYSRVDYFVYSGVTKDLKKVDKFPIAGYKIFPEDLEKEETLEVLKSMKLKILHPEVPLALRGNRKLRLNIWYEIGALYYVKGYQNVHITHATNIRTVRLAKELGFTVDITPHHLLVDREKECLTKVNPPIRDTNERLWLLQAINEVDTVVSDHAPHASFEKQQPYEICPPGIAALSFTVPFILTLVSKGIISIDRAVELISTNPARILNIPYGEIKENNYANFTIIQFKDWRYSTKYSKVIETPLDGFPLRASIYMTIIQGKVGSLEGEVFPVKGINPFGENK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Length
389 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.248 kDa
Sequence
MWIKGKAYYEGEIKEICINFDRSIKEIRANCKPDMTFTNEELILPASVDLHVHVRGAQLSYKETVATATSEAVYGGVGVIVDMPNTVPYINTPERIKERLREFQLYSRTDYGIYSGVSKEVEEIDKLPIAGYKIYPEDLEKEETRYVLEKSKKLKILHPEMPFVSKIERSLRRSYWMETAAINLVKGNMHITHITNFETLQLAKSMGFTTDITAHHLVVDGERDCISKVNPPIRDYVTRLKLFLKGLFEVDCIASDHAPHSKEEKRMNFDLCPPGIAGVSFSTPYIYSLMFKGLISIDRAVSLLSGNPSRILNIPTGKIKEGYRANFTVIKRENWRYTTKFSKVTETPMDGFSLDAKVTNVIVEGKLAFDGENVYPIRGVNIFDSSSRS
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Length
389 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
44.373 kDa
Sequence
MWIKGKAWFNNSIDTICIQIDRFIKNIKKDCKPDIEFKENQLILPASIDMHVHVRGAQLSYKETVATATSEAAYGGIGLIIDMPNTLPPVNTYERVIERIREFENYSRTDFGIYSGVTKEIEKIDTLPIAGYKIYPEDLDRTETKVLLEKSKKLKVLHPEIPLALKVPRKLRNIWMEIAALHYVQGNVHVTHITNYETVKIAKELGFSTDITPHHLLVNGERDCITKVNPPIRDYLTRLGLWKALFEVDTVVSDHAPHSKEEKNLNYDLCPPGIAAVSFTTPFIYSLVFKDLLNIERAVNLLSKNPAKILNIPYGEIRIGYVANFTIISKNDWKYRTKFSKVTETPLDNFPLEAKVEFTIVQGKIAFDGKNVLPIRGVNAFDKSSRYPV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Length
383 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
42.421 kDa
Sequence
MLKECIKIEGRAFLGGKVTRVKLGSGECKTLQLSNKYLILPGMVDIHVHFRDWGLSHKETLRGGAAAALAGGVVAVGDMPNTKPHIRTADLYKKRLEEGSALPIIYKVHMGIPQDLEELRAARPPTIKIYPEDVEAFGWGHIEKAAEACASLGCRLVLHCEDPAYFKEGERPPIAELACVERTRQMAFKTGVKIHLTHITLSQTAEAARGWATVDATPHHLLLDVENCKDSGLCHVNPRLRTPEMRKRLLAAFASGLVDIYATDHAPHTLEEKRSGAPPPGICSLDVALSLLLTLWKRGVVTLSDVVRLYSHRPARFFDLQIDVKKGYFTVVRLEEFTVRGEEFAGTCKHTPFEGFKAFGRVFATSVGGRIYFKDGDVYMINI
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Putative dihydroorotase
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Length
376 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Mass
42.633 kDa
Sequence
MRIYDPFRKKWIEEEIETPFPSKGLVATFPFVDLHVHVRLNGGEDYSSLEEASLVGGFFKVVVQPNTKPLIDSKEVLERHLDLSKNRAVEFLFAVSPFGSIEAEGERVVGFSTDGIEYDYPTLVETMKKKKKALWFDHSQMYEVDGIFYEGAPLPFQKRPRSNEAIAIARTVLTGLEYGFERFHIQHVTTKYSVEVISFLKNLAKVSCEVTPHHLFFCYEDIKNTNFKINPPLGSPEDRRALIEAVKKDVIDVLATDHAPHHEKPDDFLTAPYGSTSIEIAFPAYYTALGDLELVVKKLTKKPLEVLGVEARLTEDTLVFIDPEAEFIVDAKKFKSKGKNSMFDGVRLKGKVVALKLKGRWVMIDGEVIADQKEND
Protein
Putative dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)
Length
350 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.691 kDa
Sequence
MTDQPQQLTIRRPDDWHIHLRDGEMLEAVAPFTSEICGRAIVMPNLVPPVTSVAAARAYRERIVAAVPAAHDFTPLMTCYLTDGLDPDEIEAGFAEGVFTAAKLYPAHATTNSAHGVTSIASIAKVLERMQKIGMPLLIHGEVTDAHIDIFDREARFIETVLHPLRQQFPELKVVCEHITTQEAAAYVLEGNQYLAATITPQHLMFNRNHMLVGGIRPHLYCLPILKRNIHQQALRDAVASGHRRFFLGTDTAPHTRDRKETSCGCAGVFNAPSMLSAYATVFEEIGALAHFEAFCSENGPGFYGLPLNEDKVRLIRQPWTVPESIRVGGNGDNLVPFLAGETLNWQVVL
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Length
350 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
39.144 kDa
Sequence
MTTESYTIKIRRPDDWHIHFRDGEMLRTVVPYTSHYFGRAIVMPNLLTPITEVVSAKAYRGRILAAIPEGDNFQPLMTCYLTDTTESSQIEIGYKEGIFTACKLYPANATTNSSHGVSDIKNIYPLLAVMEKLGMPLLVHGEVTASHIDIFDREARFIEQVMEPLRNQFPALKVVFEHITTKEAAQYVLEGNNNLAATLTPQHLMFNRNHMLVGGIRPHLYCLPVLKRNVHQEALRAAVASGCDRFFLGTDSAPHAQQKKESSCGCAGVFNAPSALPAYATVFEEMNALPHFEAFCSLNGPKFYGLPVNEGFIELTRKPSTVIEHIDCNNEKLIPFLAGEDARWDVKVTD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)
Length
350 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
40.404 kDa
Sequence
MSKFVKKIKIIKPDDWHVHLRDNEILNQVIKYTGKFYKRAVIMPNLNSPITSCLKSIAYRNRILKSMHLNYKFKPLMTCYLTNSTSPKELEFGFSKKIFVAAKFYPNGCTTNSKTGIKKISDITPVLECMEKIGMPLLIHGEEINQNIDIYDREAKFIEKTLDPLRKKFPKLKIVLEHITTKESVEYIKNNDVNYLSATITPHHLMLNRNDMFYGGIQPYLYCLPILKKNKHRMALRKAISNGDKHFFLGSDTAPHLHKNKINMLGCAGIFNAPSSLLSYVKVFEEMRALKHLQSFCSENGPKFYNMPINKETITIIKKPCKIIKKINIGRNVIIPFLSGEILNWSIESD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Agrobacterium vitis (strain S4 / ATCC BAA-846)
Length
350 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.483 kDa
Sequence
MRSLTIRRPDDWHLHLRDGAMLEGVIGDTSRHFARAIIMPNLVPPVVTTADAEAYRQRILAAVPKGDRFEPLMTLYLTEQTSPDDVEEGKTTGLITAVKLYPAGATTNSHGGVRDLDKAMPVLERMAKIGLPLCVHGEVTTPEVDIFDREAVFIDTVLDPLRRRLPELKVTMEHVTTSDGIDYILSADSNLAGSITTHHLIINRNAILVGGIRPHYYCLPVAKRESHRLALRRAATSGDSRFFLGTDSAPHVDPLKECGCGCAGIYTSINTMSCLAHVFEEDEALERLEAFVSLNGPAWYGLQPNDEMITLVRRDAPVAFPAKIETGAGPVTVFDPMFPIHWDVEAAIQA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Length
350 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
40.416 kDa
Sequence
MSKFVKKIKIIKPDDWHVHLRDNEILNQVIKYTGKFYKRAVIMPNLNSPITSCLKSIAYRNRILKSMHLNYKFKPLMTCYLTNSTSPKELEFGFSKKIFVAAKFYPNGCTTNSKTGIKKISDITPVLECMEKIGMPLLIHGEEINQNIDIYDREAKFIEKTLDPLRKKFPKLKIVLEHITTKESVEYIKNNDVNYLSATITPHHLMLNRNDMFYGGIQPYLYCLPILKKNKHRMALRKAISNGDKHFFLGSDTAPHLHKNKINMLGCAGIFNAPSSLLSYVKVFEEMRALKYLQSFCSENGPKFYNMPINKETITIIKKPCKIIKKINVGRNVIIPFLSGEILNWSIESD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7)
Length
350 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
40.404 kDa
Sequence
MSKFVKKIKIIKPDDWHVHLRDNEILNQVIKYTGKFYKRAVIMPNLNSPITSCLKSIAYRNRILKSMHLNYKFKPLMTCYLTNSTSPKELEFGFSKKIFVAAKFYPNGCTTNSKTGIKKISDITPVLECMEKIGMPLLIHGEEINQNIDIYDREAKFIEKTLDPLRKKFPKLKIVLEHITTKESVEYIKNNDVNYLSATITPHHLMLNRNDMFYGGIQPYLYCLPILKKNKHRMALRKAISNGDKHFFLGSDTAPHLHKNKINMLGCAGIFNAPSSLLSYVKVFEEMRALKHLQSFCSENGPKFYNMPINKETITIIKKPCKIIKKINIGRNVIIPFLSGEILNWSIESD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
Length
349 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
39.084 kDa
Sequence
MNDTADKLTFTRPDDWHLHLRDGNAMRSVLPDTARRFARAIIMPNLKPPIVTTEQAAAYRVRILSALPAELAGRFEPLMTLYLTDTTSPEEITRAQASGIVQGIKLYPAGATTHSDAGVTDIARCEATLEKMEELDMPLLVHGEVVDPAVDVFDREKIFIDRVLTPLLQRFPGLRVVFEHITTREAVEFVQTAPNRIAATITAHHLMLNRNALFTGGLRPHHYCLPVLKREIHRQALLEAATSGHSRFFLGTDSAPHPVRDKESACGCAGIYSAHAAIEFYAEVFEQAGRLDRLEAFTSFHGPDFYGLPRNTDRISLIRESWQIPEQVELGEEKLIPLRAGEHARWKLA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Length
349 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
40.557 kDa
Sequence
MSKFLKKIKIIKPDDWHVHLRDNEILKKVSQYTGTFYKRAIIMPNLEEPITNCFRSISYRRRILNSMTPNTAFQPLMICYLTEKTSPEELQQGFFKKIFVGAKLYPHCSTTNSKYGIKNINNIYHLFNIMEKIKMPLLIHGEENNLNIDIYDREAKFIENTLKPLRKKFPELKIILEHITTEEAISYIEECNSSYLAGTITPHHLMLNRNNMFIDGIQPHLYCLPLLKRKKHQIALRNVISSGSKNFFLGSDTAPHFHKNKINTFGCAGIFNAPSSLLCYVSVFEEMNALQHFQSFCSENGPNFYNMPINKETITLVKKPHKILEKINIGKNIIVPFLAGKRLDWSIEK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.827 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPILERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.76 kDa
Sequence
MTAPSQVLKIRCPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.813 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli (strain K12)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.827 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.798 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFSPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRNGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli (strain SE11)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.826 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHNFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli (strain SMS-3-5 / SECEC)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.813 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli (strain UTI89 / UPEC)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.839 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQYFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Edwardsiella ictaluri (strain 93-146)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.671 kDa
Sequence
MTVMQHTLKIRRPDDWHLHLRDDAMLHSVLPYTSRHFSRAVVMPNLVPPITSVEQCIAYRQRILDAVPQGHAFTPLMTCYLTDALSVDTLMHGQREGVFTAAKLYPANATTNSACGVTSIPGLYPLFEAMQQSGMPLLIHGEVTQADIDIFDREARFIEQVMLPLRRDFPELRIVFEHITTREAAQFVAEGDRYLAATITPQHLMFNRNHMLVGGIHPHLYCLPILKRSVHQQALRKAATSGQTCFFLGTDSAPHLRGRKESACGCAGVFNAPTALQAYATVFEEEQALQHLEAFCSLNGPAFYGLPANEAYIELAQEPASVVDSIASGDETLTPFLAGETLRWSVRA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Enterobacter sp. (strain 638)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.922 kDa
Sequence
MTAQPQVLKIRRPDDWHIHLRDGDMLKTVVPYTSELYGRAIVMPNLAPPVTTVDAAIAYRQRILDAVPTDHDFTPLMTCYLTDSLDPNEVECGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKLGMPLLVHGEVTHAEIDIFDREARFIETVMEPLRQRLQGLKVVFEHITTKDAAEYVRDGNELLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHARHRKEASCGCAGCFNAPTALASYATVFDEMGALEHFEAFASINGPRFYGLPLNETFIELERKESQVEESIALTDDTLIPFLAGEIVHWTVKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.694 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYSSEIYARAIVMPNLAPPVTTVDAAIAYRQRILAAVPAGHNFTPLMTCYLTDSLDPDELERGFQQGVFTAAKLYPANATTNSSHGVTSTAAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIDTVMEPLRKQLPGLKVVFEHITTKDAADYVREGNDQLAATITPQHLMFNRNHMLVGGIRPHLYCLPILKRNVHQQALRELVASGFERVFLGTDSAPHARHRKEASCGCAGCFNAPTALGSYATVFEEMNALQHLEAFCSLNGPKFYGLPVNDSFIELERRESQVPDNIALNDDSLIPFLAGETIHWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Klebsiella pneumoniae (strain 342)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.863 kDa
Sequence
MTAQPQVLKIRRPDDWHIHLRDDDMLKTVVPYTSEFYGRAIVMPNLVPPVTTVAAAIAYRQRIMDAVPAGHDFTPLMTCYLTDSLDPAELERGFNEGVFTAAKLYPANATTNSSHGVTSTDAIMPVLERMEKLGMPLLVHGEVTHAEIDIFDREARFIDTVMEPLRQRLPGLKVVFEHITTKDAAEYVRDGNELLAATITPQHLMFNRNHMLVGGIRPHLYCLPVLKRNIHQQALRELVASGFSRAFLGTDSAPHARHRKEASCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSLNGPRFYGLPVNESYVELVREETTVVDSIALPNDSLVPFLAGETVRWTMKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.821 kDa
Sequence
MTAQSQVLKIRRPDDWHIHLRDDDMLKTVVPYTSEFYGRAIVMPNLVPPVTTVAAAIAYRQRIMDAVPAGHDFTPLMTCYLTDSLDPAELERGFNEGVFTAAKLYPANATTNSSHGVTSTDAIMPVLERMEKLGMPLLVHGEVTHAEIDIFDREARFIETVMEPLRQRLPGLKVVFEHITTKDAAEYVRDGNELLAATITPQHLMFNRNHMLVGGIRPHLYCLPVLKRNIHQQALRELVASGFSRAFLGTDSAPHARHRKEASCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSLNGPRFYGLPVNESYVELVREETTVVDSIALPNDTLVPFLAGETVRWTVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Yersinia pestis bv. Antiqua (strain Nepal516)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.542 kDa
Sequence
MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPITTVASAIAYRERILAAVPAGHKFTPLMTCYLTNSLDAKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNGPRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Yersinia pestis (strain Pestoides F)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.542 kDa
Sequence
MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPITTVASAIAYRERILAAVPAGHKFTPLMTCYLTNSLDAKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNGPRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.57 kDa
Sequence
MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPITTVASAIAYRERILAAVPAGHKFTPLMTCYLTNSLDVKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNGPRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Yersinia pseudotuberculosis serotype O:3 (strain YPIII)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.568 kDa
Sequence
MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPITTVASAIAYRVRILAAVPVGHKFTPLMTCYLTNSLDVKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNGPRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O139:H28 (strain E24377A / ETEC)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.826 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHNFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.813 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O45:K1 (strain S88 / ExPEC)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.839 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQYFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli (strain 55989 / EAEC)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.826 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHNFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O157:H7
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.844 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILHAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEHQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O157:H7 (strain EC4115 / EHEC)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.844 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILHAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEHQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O7:K1 (strain IAI39 / ExPEC)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.843 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDTVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O81 (strain ED1a)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.813 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O8 (strain IAI1)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.826 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHNFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli (strain K12 / MC4100 / BW2952)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.827 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli (strain K12 / DH10B)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.827 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O9:H4 (strain HS)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.813 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Escherichia coli O1:K1 / APEC
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.839 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQYFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.788 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHNFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREAHFIESVMEPLRQRLTALKVVFEHITTKDAADYVHDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shigella boydii serotype 4 (strain Sb227)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.839 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVMPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHNFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREAHFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shigella dysenteriae serotype 1 (strain Sd197)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.8 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFSAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shigella flexneri serotype 5b (strain 8401)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.871 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEAVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVTSGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shigella flexneri
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.841 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEAVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shigella sonnei (strain Ss046)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.827 kDa
Sequence
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Rhizobium etli (strain CIAT 652)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.008 kDa
Sequence
MQSITIRRPDDWHLHLRDGAMLEGVIADTSRTFARAIIMPNLVPPVVTTSDATAYRDRILKALPAGHHFQPLMTLYLTEHTSPDDVEAGAKSGLITAVKLYPAGATTNSHGGVRDLEKAMPVLERMARIGLPLCVHGEVTTPEVDIFDREAVFIDTVLDPLRKRLPELKVTMEHVTTADGIDYIKAAQSNLAGSITTHHLIINRNAILVGGIRPHYYCLPVAKRENHRLALRAAAVSGDARFFLGTDSAPHVDPLKECACGCAGIYTSINTMSCLAHVFEEEGALDKLEAFASLNGPAWYGLSPNEERITLSRQAEPVVFPAKIETGAGPVTVFDPMFPLHWQVMPQA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Rhizobium etli (strain CFN 42 / ATCC 51251)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.754 kDa
Sequence
MQSITIRRPDDWHLHLRDGAILEGVIADTSRTFARAIIMPNLVPPVVTTADAKAYRERILKALPDGHRFQPLMTLYLTEQTSPDDVEAGAASGLITAVKLYPAGATTNSHGGVRDMEKAMPVLERMAKIGLPLCVHGEVTTPDVDIFDREAVFIDTVLDPLRRRLPELKVTMEHVTTAGGIDYIKAAQGNLAGSITTHHLIINRNAILVGGIRPHYYCLPVAKRENHRLALRAAAVSGDPRFFLGTDSAPHVDPLKECACGCAGIYTSINTMSCLAHVFEEEGALDRLEAFASLNGPAWYGLSPNEERITLSKQADPVVFPAKIETGAGAVTVFDPMVPLHWQVSASA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Rhizobium leguminosarum bv. viciae (strain 3841)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.352 kDa
Sequence
MQSITIRRPDDWHLHLRDGAMLEGVIADTSRTFARAIIMPNLVPPVVTSADAKAYRERILKALPDSHRFQPLMTLYLTEHTSPDDVEEGKNSGLITAVKLYPAGATTNSHGGVRDMEKAMPVLERMAKIGLPLCVHGEVTTPEVDIFDREAVFIDTVLDPLRQRLPELKVTMEHVTTSDGVDYIKAARGNLAGSITTHHLIINRNAILVGGIRPHYYCLPVAKRENHRLALRAAAVSGDPRFFLGTDSAPHVDPLKECACGCAGIYTSVNTMSCLAHVFEQEGALERLEAFVSLNGPAWYGLQPNEERITLSRQAEPVVFPARIETGAGPVTVFDPMFPLHWQVVQQA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella agona (strain SL483)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.649 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHAEVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRDLVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQVPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.735 kDa
Sequence
MTAPSQVLKIHRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNHMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAVVFEEMNALAHFEAFCSLNGPQFYGLPVNKGWVELVRDEQQIPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella choleraesuis (strain SC-B67)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.679 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTTLKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQVPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas aeruginosa (strain PA7)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.39 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAALANTVGDAARTFGRAIVMPNLVPPVRNAAEADAYRQRILAARPAASRFEPLMVLYLTDRTSAEEIRTAKASGFVHAAKLYPAGATTNSDSGVTRIDNVFAALEAMAEVGMPLLVHGEVTRAEVDVFDREKQFIDEHLRRVVERFPTLKVVFEHITTGDAAQFVREAPANVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQEALLDAAVSGNPKFFLGTDSAPHARHAKEAACGCAGCYTAYAAIELYAEAFEQRNALDKLEGFASLHGPDFYGLPRNTDRITLVREQWQAPASLPFGDFDVVPLRAGETLRWKLLEAEA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas aeruginosa (strain LESB58)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.377 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAALANTVGDAARTFGRAIVMPNLVPPVRNAAEADAYRQRILAARPAASRFEPLMVLYLTDRTSAEEIRTAKASGFVHAAKLYPAGATTNSDSGVTRIDNIFEALEAMAEVGMPLLVHGEVTRAEVDVFDREKQFIDEHLRRVVERFPTLKVVFEHITTGDAAQFVREAPANVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQEALLDAAVSGNPKFFLGTDSAPHARHAKEAACGCAGCYSAYAAIELYAEAFEQRNALDKLEGFASLHGPDFYGLPRNTDRITLVREEWQAPASLPFGDFDVVPLRAGETLRWKLLEAGA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas aeruginosa (strain UCBPP-PA14)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.407 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAALANTVGDAARTFGRAIVMPNLVPPVRNAAEADAYRQRILAARPAASRFEPLMVLYLTDRTSAEEIRTAKASGFVHAAKLYPAGATTNSDSGVTRIDNIFEALEAMAEVGMPLLVHGEVTRAEVDVFDREKQFIDEHLRRVVERFPTLKVVFEHITTGDAAQFVREAPANVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQEALLDAAVSGNPKFFLGTDSAPHARHAKETACGCAGCYSAYAAIELYAEAFEQRNALDKLEGFASLHGPDFYGLPRNTDRITLVREEWQAPASLPFGDFDVVPLRAGETLRWKLLEAGA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.407 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAALANTVGDAARTFGRAIVMPNLVPPVRNAAEADAYRQRILAARPAASRFEPLMVLYLTDRTSTEEIRTAKASGFVHAAKLYPAGATTNSDSGVTRIDNIFEALEAMAEVGMPLLVHGEVTRAEVDVFDREKQFIDEHLRRVVERFPTLKVVFEHITTGDAAQFVREAPANVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQEALLDAAVSGNPKFFLGTDSAPHARHAKEAACGCAGCYSAYAAIELYAEAFEQRNALDKLEGFASLHGPDFYGLPRNTDRITLVREEWQAPASLPFGDFDVVPLRAGETLRWKLLEAGA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas entomophila (strain L48)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.473 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAVLQHTVGDVARTFARAIIMPNLVPPVRNALEAGGYRERILAARPAGSRFEPLMVLYLTDRTSPEDIRAAKASGFVYAAKLYPAGATTNSDSGVTSIDNIFPAIEALAETGMPLLVHGEVTRSEIDVFDREKRFIDEHMRRLVERFPTLKVVFEHITTADAAQFVTEAPANVGATITAQHLLYNRNHMLVGGIRPHFYCLPILKRNTHQVALLDAATSGNPKFFLGTDSAPHAKHAKEAACGCAGCYTAYAAIELYAEAFEQRNALDKLEGFASKHGPDFYGLPRNTDTITLVRDEWTAPDSLPFGDNTVIPLRAGEKLRWRLLEDNA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.416 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAVLPNTVADVARTFGRAIIMPNLVPPVRNAAEADAYRQRILAARPAGSRFEPLMVLYLTDRTQPEEIRAAKACGFVHAAKLYPAGATTNSDSGVTSIDKIFPVLEAMAEVGLPLLIHGEVTRGDVDVFDREKIFIDEHMRRVVERFPSLKVVFEHITTAEAVQFVKEASANVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQEALLDAATSGNAKFFLGTDSAPHAQHAKEAACGCAGCYSAYAAIELYAEAFEQRNALDQLEAFASLNGPRFYGLPANTDSITLVREEWTAPASLPFGELTVIPLRAGEKLRWRLLEDHS
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas fluorescens (strain SBW25)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.409 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAALPHTVADVARTFGRAIIMPNLVPPVRNAEQADAYRQRILAARPAGSRFEPLMVLYLTDRTQPEEIREAKASGFVHAAKLYPAGATTNSDSGVTSIDKILPAIEAMAEVGMPLLIHGEVTRGDVDVFDREKIFIDEHMRRVVELFPTLKVVFEHITTADAVQFVTEASANVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQVALLDAATSGNPKFFLGTDSAPHAQHAKEAACGCAGCYTAFAAIELYAEAFEQRNALDKLEGFASINGPRFYGLPANTDRITLVREDWTAPASLPFGELTVIPLRAGETLRWRLLEESK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas mendocina (strain ymp)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.171 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAVLPHTVGDAARTFGRAIIMPNLVPPVRNAAEADAYRQRILAARPAGSRFEPLMVLYLTDNTSPEDVRAAKASGFVHAAKLYPAGATTNSDSGVTSIDKIFPALEAMAEVGMLLLVHGEVTRAEIDVFDREKAFIDEHLTRVVERFPTLKVVFEHITTRDAVQFVEAASANVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNVHQEALLDAATSGNVKFFLGTDSAPHAKHAKEAACGCAGCYTAFAAIELYAEAFEQRNALDKLEAFASFHGPDFYGLPRNTDSITLVREEWTVPASLPLGENSVVPLRAGETLRWKLLEGQA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.389 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAVLPHTVGDVARTFARAIIMPNLVPPVRTANEAGAYRERILAARPAGSRFEPLMVLYLTDNISPEDIRAAKASGFVYAAKLYPAGATTNSDSGVTSIDNIFPAIEAMAEVGMPLLVHGEVTRSEIDVFDREKRFIDEHMRRVVERFPTLKVVFEHITTSDAAQFVTEAPANVGATITAQHLLYNRNHMLVGGIRPHFYCLPILKRNTHQVALLDAATSGNPKFFLGTDSAPHARHAKEAACGCAGCYTAYAAIEMYAEAFEQRNALDKLEGFASLHGPAFYGLPANTDTITLVREEWTAPESLPFGEQTVVPLRAGEKLRWRLLEKNA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas fluorescens (strain Pf0-1)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.48 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAVLTNTVADVARTFGRAIIMPNLVPPVRNAAEADGYRQRILAARPAGSRFEPLMVLYLTDRTQPEEIREAKASGFVHAAKLYPAGATTNSDSGVTSIDKIFPVLEAMAEAGMPLLIHGEVTRGDVDVFDREKIFIDEHMRRVVERFPTLKVVFEHITTGDAVQFVNEASANVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQEALLDAATSGSAKFFLGTDSAPHAQHAKEAACGCAGCYTAYAAIELYAEAFEQRNALDKLEAFASLNGPRFYGLPANTDRITLVRDEWTAPTSLPFGELTVIPLRAGEKLRWRLLEEHA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas putida (strain GB-1)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.31 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAVLPHTVGDVARTFARAIIMPNLVPPVRNAAEAGAYRERILAARPAGSRFEPLMVLYLTDRTSPEDVRAAKASGIVYAAKLYPAGATTNSDSGVTSIDNIFPAIEALAEVGMPLLVHGEVTRSEIDVFDREKRFIDEHMRRVVERFPTLKVVFEHITTSDAAQFVTEAPANVGATITAQHLLYNRNHMLVGGIRPHFYCLPILKRNTHQVALLDAATSGNPKFFLGTDSAPHARHAKEAACGCAGCYTAYAAIEMYAEAFEQRNALDKLEGFASLHGPAFYGLPANTDTITLVREEWTAPDSLPFGEQTVVPLRAGEKLRWRLLEENA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.415 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAVLPHTVGDVARTFARAIIMPNLVPPVRNVTEAGAYRERILAARPAGSRFEPLMVLYLTDRTSPEDVRAAKASGFVYAAKLYPAGATTNSDSGVTSIDNIFPAIEALAEVGMPLLVHGEVTRSEIDVFDREKRFIDEHMRRVVERFPTLKVVFEHITTSDAAQFVTEAPANVGATITAQHLLYNRNHMLVGGIRPHFYCLPILKRNTHQVALLDAATSGNPKFFLGTDSAPHARHAKEAACGCAGCYTAYAAIEMYAEAFEQRNALDKLEGFASLHGPAFYGLPANTDTITLVREEWTAPESLPFGEQTVVPLRAGEKLRWRLLEKNA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas putida (strain W619)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.409 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAVLPHTVGDVARTFARAIIMPNLVPPVRNADEAGAYRERILNARPAGSRFEPLMVLYLTDRTSPEDIRAAKASGIVYAAKLYPAGATTNSDSGVTSIDNIFPAIEALAEVGMPLLVHGEVTRSEIDVFDREKRFIDEHMRRLVERFPTLKVVFEHITTADAAQFVTEAPANVGATITAQHLLYNRNHMLVGGIRPHFYCLPILKRNTHQVALLDAATSGNPKFFLGTDSAPHARHAKEAACGCAGCYTAYAAIEMYAEAFEQRNALDKLEGFASLHGPAFYGLPANTDTITLVREEWTAPDSLPFGEQTVIPLRAGEKLRWRLLEDNA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.768 kDa
Sequence
MTVQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLTPPITTVASAIAYRERILAAIPAGHKFTPLMTCYLTNTLDVNELTRGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRRQFPELKIVFEHITTKDAADYVLAGNPFLGATITPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQDALRQAVASGSDRFFLGTDSAPHTKHRKESSCGCAGVFNAPSALPAYASVFEEMNALQHLEAFCSLNGPRFYGLPVNEDFVELVRVPFQQPEEISLGNESIIPFLAGQTINWSVKA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.598 kDa
Sequence
MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPITTVASAIAYRERILAAVPVGHKFTPLMTCYLTNSLDVKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNGPRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Yersinia pestis bv. Antiqua (strain Antiqua)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.542 kDa
Sequence
MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPITTVASAIAYRERILAAVPAGHKFTPLMTCYLTNSLDAKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNGPRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Yersinia pseudotuberculosis serotype IB (strain PB1/+)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.57 kDa
Sequence
MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPITTVASAIAYRERILAAVPAGHKFTPLMTCYLTNSLDVKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNGPRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Yersinia pestis
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.542 kDa
Sequence
MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPITTVASAIAYRERILAAVPAGHKFTPLMTCYLTNSLDAKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNGPRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Yersinia pestis bv. Antiqua (strain Angola)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.542 kDa
Sequence
MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPITTVASAIAYRERILAAVPAGHKFTPLMTCYLTNSLDAKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNGPRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Synechococcus sp. (strain CC9605)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.466 kDa
Sequence
MSDQISIIAPDDWHVHLRDGEMLNQVVAHTARRFQRAIVMPNLRPPVTTVAAAQAYRDRIQAACPADLEFTPLMTAYLTDSIAPAELETGFREGVFAAAKLYPANATTNSAAGVTDLLQIDPVLETMARIGMPLLIHGEVTDPEIDIFDREAAFIERHLEPLRERHPELKVVLEHITTEQAVQYVSSADRHLAATITPHHLHINRNAMFAGGLRSDFYCLPVAKRECHRQALRRAATSGDPSFFLGTDTAPHERSSKESACGCAGIFNAPFALESYAQVFDQEGALEHFEAFTSLNGPAFYKLPANTHRITLQRRDHLVPELVNGLVPFHAGEILSWAVANAPDQVQL
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Coxiella burnetii (strain RSA 331 / Henzerling II)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.675 kDa
Sequence
MKKITLIRPDDWHCHLRDGSYLPRTVADIAAQFNRAIVMPNLVPPITTVQQAKAYYDRIKAHVPKSSNFEPLMTLYLTESTPQQEIKAAQQSGIIVACKLYPAGATTHSQAGVKDLKAIYTLLETMQSVDLPLLIHGEVVDYAVDIFDREAVFIERELLPLVETFPQLRIVFEHISTKIAVDFVLEAPSKLGATITPHHLLFNRNDLLSGSIRPHYYCLPILKTSEDQMALIQAATSGNPKFFLGTDSAPHSQTKKQSICGSAGIYNAPAAIALYAEIFASQNALDKLEGFASRFGAEFYGLPLNNSQITLIHQPWQVAESLPFGNELVVPLFAGQTLQWQIKSHEHK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Cronobacter sakazakii (strain ATCC BAA-894)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.591 kDa
Sequence
MTAQPQVLTIRRPDDWHVHLRDGDMLKTVVPYTSETYGRAIVMPNLAPPVTTVEAAIAYRQRILDAVPEHHAFEPLMTCYLTDTLDADELERGFQQGVFTAAKLYPANATTNSSHGVTSVDNIMTVLERMEKLGMPLLVHGEVTHSEVDIFDREARFIETVMEPLRKRLQGLKVVFEHITTKDAADYVREGNSLLGATITPQHLMFNRNHMLAGGIRPHLYCLPILKRNVHQQALRELVASGCERVFLGTDSAPHARHRKETSCGCAGCFNAPSALGAYATVFEEMNALAHFEAFASLNGPGFYGLPVNEGTVTLVREESVMPETIAIADDTLVPFLAGEAVRWTVKR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella dublin (strain CT_02021853)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.633 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHAEVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNAGWVELVRDEQQVPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella enteritidis PT4 (strain P125109)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.633 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHAEVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNAGWVELVRDEQQVPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella gallinarum (strain 287/91 / NCTC 13346)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.633 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHAEVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNAGWVELVRDEQQVPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella heidelberg (strain SL476)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.604 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILNAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTTLKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNAGWVELVRDEQQIPGNIALADDSLVPFLAGETIRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella newport (strain SL254)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.688 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTTLKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQHVPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella paratyphi A (strain ATCC 9150 / SARB42)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.642 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGSDNLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRDLVASGFTRAFLGTDSAPHSRHRKETRCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQIPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.725 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTTLKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALCSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQVPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella paratyphi C (strain RKS4594)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.679 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTTLKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQVPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella paratyphi A (strain AKU_12601)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.642 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGSDNLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRDLVASGFTRAFLGTDSAPHSRHRKETRCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQIPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella schwarzengrund (strain CVM19633)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.663 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQIPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella typhi
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.69 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGSYNLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRDLVASGFTRAFLGTDSAPHSRHRKETRCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQIPENIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.605 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGIPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTALKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPMNTGWVELVRDEQQIPGNIALADDSLVPFLAGETVRWSVKK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Serratia proteamaculans (strain 568)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.518 kDa
Sequence
MTAQPQALKIRRPDDWHIHLRDDDMLKTVLPYTSQVFGRAIVMPNLALPITTVAAACAYRDRILAAVPQGHDFTPLMTCYLTNSLDAAELVNGFEQGVFTAAKLYPANATTNSSHGVSDVKAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIEQVMEPIRQQFPELKIVFEHITTKEAAQYVQEGNRFLGATITPQHLMFNRNHMLVGGIRPHLFCLPILKRNIHQDALRKAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPNAIPAYASVFEQLGALDHLEAFCSLNGPRFYGLPVNTDFIELQRVATTQPEEIAMGSETVIPFLAGESLSWSVKA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Azotobacter vinelandii (strain DJ / ATCC BAA-1303)
Length
348 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.856 kDa
Sequence
MPDRLILLRPDDWHIHLRDGAALSRTVTDAARTFGRAIVMPNLVPPVRNASEAGAYRQRIQAARPADSRFEPLMTLYLTDKTSPEDIRTAKAQGFVHAAKLYPAGATTNSDAGVTRIDNIFPILEAMAEAGLPLLVHGEVTHSEVDVFDREKRFIDENLVRIIEHFPTLKVVFEHITTRDAVQFVETSSSNVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRRTHQEALLDAATSGNTKFFLGTDSAPHARHAKEAACGCAGCYTAYAAIELYAEAFEQRSALDRLEAFASHHGADFYGIPRNTDHITLIREEWTAPACMTFGEHSLVPLRAGEKLRWRLLEEKM
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Jannaschia sp. (strain CCS1)
Length
347 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.943 kDa
Sequence
MTQSLTIRRPDDWHLHLRDGAMMRAVLPETARHFARAIIMPNLVPPVVTAQDALAYRDRIEAALPDGADFTPLMTLYLTEQTDPDDVEAAFADGLIHAVKLYPAGATTNSQSGVATLKNVYPVLERMAQIGLPLCIHGEVTDPQVDIFDREQAFIDTVLIPLRADLPDLKVTLEHITTSHGIDYVVGADGDIAGTITTHHLMINRNHMLVGGIRPHYYCLPIVKRASHQHALRRAATSGHPRFFLGTDSAPHLDGAKETACGCAGVFSATNTMSCLAHVFDEDGALVNLEAFTSLNGPARYGLAPNAATMTLEKRDHPTNYPAKFDTDDGPLTLFDPSTPLYWHVKD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
Length
347 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.615 kDa
Sequence
MTAQHTILKIRRPDDWHIHLRDDRMLETVLPYTSRFFGRAIVMPNLTPPITSVASAIAYRQRILAAVPQGDNFHPLMTCYLTDTLDANEIVSGFEQGVFTAAKLYPANATTNSSHGVTSVATISGILEKMQKIGMPLLIHGEVTDPAIDIFDREARFIETILEPLRQDFPELKVVLEHITTKEAAEYVIAGNDYLAATITPQHLMFNRNHMLVGGIRTHLYCLPILKRNTHQQALREAVASGCDRLFLGTDSAPHAKHRKESSCGCAGVFNAQAALSTYATVFEEMNALDKLEAFCSLNGPRFYGLPVNDSWIELHREAVTFPEEIALGDESLIPFLAGQSLNWSVR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pectobacterium carotovorum subsp. carotovorum (strain PC1)
Length
347 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.643 kDa
Sequence
MTAQPTILKIRRPDDWHIHLRDDRMLETVLPYTSRFFGRAIVMPNLTPPITTVASAIAYRQRILAAVPQGDDFHPLMTCYLTDALDANEIVSGFEQGVFTAAKLYPANATTNSSHGVTSVANISGILEKMQKIGMPLLIHGEVTDAAVDIFDREARFIETVLEPLRQQFPELKVVLEHITTKEAAQYVVEGNDYLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNTHQQALREAVASGCERLFLGTDSAPHAKHRKESSCGCAGVFNAQAALSTYATVFEEMNALDKLEAFCSLNGPRFYGLPVNDSWIELYRETVTFPEEISLGDESLIPFLAGQSLNWSVR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Rhizobium meliloti (strain 1021)
Length
347 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.106 kDa
Sequence
MQDLVIRRPDDWHLHLRDGGMLRGVIADTSRHFARAIIMPNLVPPVVTSADAAAYRERILAAIPAGDRFEPLMTLYLTEGTDPGDVEAGFRSGLVKAVKLYPAGATTNSSSGVRDIDKAMPVLERMAEIGLPLCVHGEVTTAEVDIFDREAVFIETVLDPLRRRLPDLRITMEHVTTKDGVDYIREHAANLAGSITTHHLIINRNAILVGGIKPHYYCLPVAKREAHRLALRQAAISGDVRFFLGTDSAPHVDPLKECACGCAGIYTSINTLSCLAHVFEEEGALDRLEAFTSLNGPAWYGLPANEETITLRKQEEPVSYPARIETEAGPVTVFDPMFPLHWAVTQA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Acidovorax sp. (strain JS42)
Length
347 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.041 kDa
Sequence
MTATTDTLTITRPDDWHLHVRDGEPLRTVVPHTAAQFGRAIIMPNLRPPVTTAQQAAEYKQRILAAVPEGVAFEPLMTLYLTDNLPPDEIARARDAGVVAAKLYPAGATTNSDAGVTDLRKTYKTLEAMQKAGLLLLVHGEVTSSDIDLFDREAVFIEQQLIPLRRHFPELKIVFEHITTKEAAQYVKEAGRFTAATITAHHLLYNRNAIFTGGIRPHYYCLPVLKREVHRQALVQAATSGSDKFFLGTDSAPHPAHLKEHATGCAGCYTAHAAIEMYAEAFDNAGALDKLEGFASVHGPAFYGLPRNTGTVTLRRESWTPPDSFAFGEAALKPLRAGEALPWRLVA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)
Length
347 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.238 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAVLPHTVADVARTFGRAIIMPNLVPPVRNAQQADAYRQRILAARPAGSRFEPLMVLYLTDQTTPEDIRTAKASGFVHAAKLYPAGATTNSDSGVTSIDKIFPALEAMAEVGMLLLVHGEVTRGEIDVFDREKVFIDEHLRRVVERFPTLKVVFEHITTGEAVQFVNEASANVAATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQASLLDAATSGSGKFFLGTDSAPHAQHAKENACGCAGCYTAYAAIELYAEAFEQRNALDKLEGFASLHGPAFYGLPANQDTITLVRDEWTAPASLPFGELTVIPLRAGEKLRWRLEEHA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Length
347 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.239 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAVLPHTVADVARTFGRAIIMPNLVPPVRNAQQADAYRQRILAARPAGSRFEPLMVLYLTDQTTPEDIRTAKASGFVHAAKLYPAGATTNSDSGVTSIDKIFPALEAMAEVGMLLLVHGEVTRGEIDVFDREKVFIDEHLRRVVERFPTLKVVFEHITTGDAVQFVNEASANVAATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQVALLDAATSGSGKFFLGTDSAPHAQHAKENACGCAGCYTAYAAIELYAEAFEQRNALDKLEGFASLHGPAFYGLPANQDTITLVRDEWTAPTSLPFGELTVIPLRAGETLRWRLEEHA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas syringae pv. syringae (strain B728a)
Length
347 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.253 kDa
Sequence
MSDRLTLLRPDDWHIHLRDGAVLPHTVADVARTFGRAIIMPNLVPPVRNAQQADAYRQRILAARPATSRFEPLMVLYLTDQTTPDDIRTAKASGFVYAAKLYPAGATTNSDSGVTSIDKIFPALEAMADVGMLLLVHGEVTRGEIDVFDREKVFIDEHLRRVVERFPSLKVVFEHITTGEAVQFVNEASANVAATITAHHLLYNRNHMLVGGIRPHFYCLPILKRNTHQTALLDAATSGSGKFFLGTDSAPHAQHAKENACGCAGCYTAYAAIELYAEAFEQRNALDKLEGFASLHGPAFYGLPANQDTITLVRDEWTAPASLPFGELTVIPLRAGETLRWRLEEHA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudomonas stutzeri (strain A1501)
Length
347 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.222 kDa
Sequence
MSARLTLLRPDDWHIHLRDGAALPHTVADAARQFARAIIMPNLVPPVRNADEAEAYRQRILAARPAGSRFEPLMVLYLTDSTTPDDIRRAKASGFVHAAKLYPAGATTNSASGVTAIDNIFGVLETMAEVGLPLLVHGEVTRSEIDIFDREKYFIDEQLSRVTARFPTLKVVFEHITTRDAVQFVQAAGANVGATITAHHLLYNRNHMLVGGIRPHLFCLPVLKRNLHQEALLDAATSGSPKFFLGTDSAPHAQHAKEAACGCAGCYTAFAAIELYAEAFEQRQALDKLEPFASHFGPDFYGLPRNTDEITLVRTEWDVPASLPFGEQVVVPLRAGERLHWRLESNA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
Length
347 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.731 kDa
Sequence
MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDTLDPDELERGFREGVFTAAKLYPANATTNSSHGVTSVDTIMPVLERMEKLGMPLLVHGEVTHADIDIFDREARFIETVMEPLRQRLTALKVVFEHITTKDAAEYVRDGNELLAATITPQHLMFNRNHMLVGGIRPHLYCLPILKRNVHQQALRELVASGFSRAFLGTDSAPHARHRKETSCGCAGCFNAPTALGSYATVFEEMNALAHFEAFCSLNGPRFYGLSVNETYVELVREEQLVPESITLADDSLVPFLGGERVRWSVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Sinorhizobium medicae (strain WSM419)
Length
347 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.366 kDa
Sequence
MQHLVIRRPDDWHLHLRDGGMLRGVIADTSRHFARAIIMPNLVPPVVTSADAATYRERILAAIPAGHRFEPLMTLYLTEGTDPDDVEEGFRSGLVKAVKLYPAGATTNSSSGVRDIDKAMPVLERMAEVGVPLCVHGEVTTADVDIFDREAVFIETVLDPLRRRLPDLRITMEHVTTKDGVDYIREHAVNLAGSITTHHLIINRNAILVGGIKPHYYCLPVAKREMHRLALREAAISGDVRFFLGTDSAPHVDPLKECACGCAGIYTSINSLSCLAHVFEEEGALDRLEAFTSLNGPAWYGLPPNEETITLRKQEEPVGYPAKIETEAGPVTVFDPMFPLYWTVIEA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Delftia acidovorans (strain DSM 14801 / SPH-1)
Length
346 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.233 kDa
Sequence
MTASTNTLTITRPDDWHLHVRDGEAMRSVVPHTAAQFARAIIMPNLKPPVTTAEQALEYKQRILSAVPEGMAFEPLMTLYLTDNLPPEEIVRAKAAGVVACKLYPAGATTNSDHGVTDLRKIYPTLEAMQREGLLLLVHGEVTSSDIDLFDREAAFIDQHLIPLRRDFPELKIVFEHITTREAAQYVTEADRFVGATITPQHLLFNRNAIFTGGIRPHYYCLPVLKRETHRLALVEAATSGLPKFFLGTDSAPHAAHLKEHATGCAGCYSAHAAIEMYAEAFDNAGALDKLEAFASFNGPDFYSLPRNTGKITLVRESWTPPDSFAFGEAQLKPLRSGEALPWKLV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199)
Length
346 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.002 kDa
Sequence
MTETLTIRRPDDWHVHLRDRDVLRGVVPYTARQFARAIVMPNLSPPMTDVAGVAAYRDRILAALPQGSAFTPLMTLYLTDSTDIEEVARGFAEGVFVAAKLYPAHATTGSAHGVTDIRNIYPVLEKMQEIGMPLLIHGEVTDSHVDIFDREAVFIERTLTRLVADMPALRIVFEHITTEEAAQFVEGAGDSIAATITPQHLHINRNAMLVGGIRPHAFCLPVAKREKHRLALRKLATSGFSRVFLGTDTAPHAKHLKEAACGCAGIFNAPFALESYVTVFDEEGALDRFEAFASLNGPAFYRMPVNEDRIVLERAPIEVPEVIDCNGTAIVPFHAGETLGWRIAAA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Rhizobium leguminosarum bv. trifolii (strain WSM2304)
Length
346 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.931 kDa
Sequence
MQSITIRRPDDWHLHLRDGAMLEGVIADTSRTFARAIIMPNLVPPVVTTSDATAYRERILKALPAGHRFQPLMTLYLTEHTSPDDVEAGARSGLITAVKLYPAGATTNSHGGVRDMEKAMPVLERMAAIGLPLCVHGEVTTPEVDIFDREAVFIDTVLDPLRRRLPELKVTMEHVTTSDGIDYIKAAKANLAGSITSHHLIINRNAILVGGIRPHYYCLPVAKRENHRLALRAAAVSGDARFFLGTDSAPHVDPLKECACGCAGIYTSINTMSCLAHVFEEEDALDRLEAFTSLNGPAWYGLQPNEERITLSRQAEPVVFPAKIETGAGSVTVFDPMYPLHWHVVA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
Length
346 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.417 kDa
Sequence
MTQSLTIRRPDDWHLHLRDGAMLEGVLPETTRHFARAIVMPNLVPPVVTGAEAAAYRERIMAALPAGARFEPLMVLYLTETTDPADVRAAAASGLVKAVKLYPAGATTNSASGVRDFDRVRGVLETMAEIGLPLCVHGEVTDPAVDIFDREAVFLERVLEPIRRATPGLRVVLEHVTTRDGLDYVRGGGPDMAGTLTTHHLIINRNHILAGGIRPHYYCLPVAKRETHRLALREAATGGEGCFFLGTDSAPHADAAKESACGCAGCFTATNTLSILAHVFEEEGALDRLEGFVALNGPAFYRLPPNEERITLRKGEPLVLPARIETGAGPVTLFDPGFPLLWHVES
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
Length
346 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.657 kDa
Sequence
MTQSLTIRRPDDWHLHLRDGAMLAAVLPETARHFARAIVMPNLVPPVVTGAQAAAYRDRILATLPKGMNFEPLMTLYLTEQTDPDDLAAAHTSGLITSVKLYPAGATTNSASGVKDFDKVRPVLERMAEIGCPLCVHGEVTDREIDIFDREAVFIDRVLDPIRRATPGLRVIMEHITTKDGADYVAANPEGLGATITVQHLMFDRNDMLVGGMRPHYYCLPILKRRHHREALVAAATSGDARYFLGTDSAPHPTHAKEAECCAAGCFTAPIALSCLAHVFEEAGALDKLEGFTSLNGPAFYGLPVNADTITLSKADPLDIPKTLPAGEHTVTVFDPGVPLHWRVTR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Ruegeria sp. (strain TM1040)
Length
346 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.869 kDa
Sequence
MTQSLTITRPDDWHLHLRDGDMLRAVLPETARHFGRAIIMPNLVPPVVTGAEASAYRDRILAALPEGMTFEPLMTLYLTEDTDPADVAAAHASGLVKAVKLYPAGATTNSSSGVRDFDKVRPVLEKMAEIGLPLCTHGEVTDHDIDIFDREAVFIDRVLDPIRQSTPGLRVVMEHITTKDAADYVRSQDKDLGATITTHHLIINRNHILVGGIKPHYYCLPVAKREEHRLALRQAATSGDARFFLGTDSAPHTDANKLQTCGCAGCFTATNTMALLAHVFEEEGALDKLEGFASKNGPAFYRLPENDGQITLVKQDAPVAFPEQIDTPDGPVTVFDPSFAVHWTVT
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Agrobacterium radiobacter (strain K84 / ATCC BAA-868)
Length
346 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.039 kDa
Sequence
MQKLTIRRPDDWHLHLRDGAMLEGVIGDTSRHFARAIIMPNLVPPVVTTADATAYRERILKALPAGDRFQPLMTLYLTEHTNPDDVEEGKKSGLITAVKLYPAGATTNSHGGVRNLDKAMPTLERMAKIGLPLCVHGEVTTPEVDIFDREAVFIETVLDPLRQRLPELKVTMEHVTTSDGIDYIKSAKANLAGSITTHHLIINRNAILVGGIRPHYYCLPVAKRESHRLALRAAATSGDSRFFLGTDSAPHVDPLKECACGCAGIYTSINTMSCLAHVFEQDGALDKLEAFASLNGPAWYGLAPNEERITLIRRVESVTFPEKIETGAGTVTVFDPMFPLHWDVEG
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6)
Length
346 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.732 kDa
Sequence
MEKITLTRPDDWHLHLRDGEALKAVLPDTVRQFARAIVMPNLKPPVRTVAEAAAYHDRILAAIPPGRTFEPLMTLYLTDNTSPAEIQAAKESGFVKAVKYYPAGATTNSDLGVTDIRKCDAVFEAMQTVDLPLLLHGEVTDHRVDVFDREKVFIETYLRPLKERFPQLRIVLEHITTKDAVEFVLASDEKVAATITPQHLLFNRNSIFQGGIRPHFYCLPILKRETHREALLEAATSGNPKFFLGTDSAPHGRDRKESDCGCAGCYSALHALELYATVFEAADALDKLEGFASFYGPDFYQLPRNTEKITLTKTPWQIPDALPFPESSLVPLWAGQELSWKFAPVA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Synechococcus sp. (strain RCC307)
Length
346 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.412 kDa
Sequence
MTPAPDQLVLRRPDDWHVHLRDDVMLEQVLPATARQFARAIVMPNLRPPVTTVDAAIAYRQRIEAALPDGMAFTPLMTAYLTDDISPDELERGHREGVFTAAKLYPANATTNSAAGVSDLACITAVLERMQAIDMPLLIHGEVTDPDIDIFDREAVFIERHLIPLRRQFPQLRVVFEHITTEQAAQFVVDGDPLMAATITPHHLHINRNAMFQGGLRSDFYCLPVAKRERHRLALRQAATSGDPSFFLGTDSAPHPRAGKESSCGCAGIYNAPYALESYLAVFEAEGALQHFEAFASENGPRFYKLPLNEDTITLKRTAQLVPAQLEGQGLVPFHASEVLDWRLAD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Chelativorans sp. (strain BNC1)
Length
346 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.286 kDa
Sequence
MKTLTIRQPDDWHLHLRDGSVLQAVAEHSAAHFARAIIMPNLVPPVVTTRDAAAYRERILAALSEGSAFTPLMTLYLTESSCADDIEAGFRSGLIKAVKLYPAGATTNSQSGVRNIEAVYPVLERMAKIGLPLCVHGEVTDPAVDIFDREAVFIERVLQPLRRRLPELRIVMEHVTTKDGVDFALSQDENVGATITTHHLIINRNAILAGGIRPHYYCLPVAKRESHRLALRAAAISGEGRFFLGTDSAPHLDPLKECACGCAGVFNAPNTMACLAHVFEEEGALDRLEAFTSLNGPAFYRLPPNEKRITLRRYDEPLEMERKVSVGDEAITVFDPMFPIHWKVED
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Laribacter hongkongensis (strain HLHK9)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.353 kDa
Sequence
MHTLTLTRPDDWHLHLRDGEALAAVAAYSAREFARAIVMPNLKPPVTTVVQAAAYRERILAALPPGGPAFEPLMTLYLTDNTPPAEIDRVAESGFVHALKLYPAGATTNSDAGVTSLSGCLPTLTRMAELGVPLLVHGEVTDPQIDVFDREAVFIDTVLQPLLAELPTLRVVMEHITTRQAAEFVLAAPDNIAATVTPQHMLMNRNALFTGGLRPHHYCLPVLKREEHRAAIARAVTSGSTRFFLGTDSAPHARHAKEAACGCAGIFSAHAALPLYAEAFEDAGALDRLEAFASFNGPDFYRLPRNTGTVTLKREEWTVPASLPYGNDTLVPLRAGETLRWQLAG
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella frigidimarina (strain NCIMB 400)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.674 kDa
Sequence
MTQITLTTPDDWHLHFRDGDMLGETVPATARLFQRAIVMPNLVPPVTTAAMALAYRDRILAARPQGSNFEPLMTLFLTNNTSAQDIIDAKAAGVVAGKLYPAGATTNSDAAVKALDELFPIFEVMAQQGMLLLVHGEVTESHIDIFDREKMFIDRYLSRIVEAIPSLKVVFEHITTKEAAEFVAEASANVAATITPQHLLLNRNDLLVGGVRPHNFCLPVLKRNIHQHALQAAVATGSSKFFLGTDSAPHEKHRKESACGCAGCYSAWSALELYAQVFDNLGALDKLEGFASLHGADFYGLPRNSGTVTLVKQEWTVPEEIILPNGNPIVPFFAGQKVNWKVKTA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella halifaxensis (strain HAW-EB4)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.868 kDa
Sequence
MTQITLLTPDDWHLHFRDGDMLQETVPATARLFQRAIVMPNLLPPVTDAKMVTEYRERILAARPAGSTFEPLMTIFLTNNTTEQDIIDAKAAGVVAAKLYPAGATTNSDAAVKALDALFPVFEAMAKHGMLLLVHGEVTESHIDIFDREAMFIERYLARIVAAFPALKVVFEHITTKDAADFVMSAPDNVAATITPQHLLLNRNDLLVGGVRPHNFCLPVLKRSTHQEALRAVIATGSSKFFLGTDSAPHEKHRKESACGCAGCYSAWSALELYAQVFDDLGALDKLEGFASLHGPDFYGLPRNTSTVTLVKEKWTVPSEIILPNGNPIVPFFAGEEVNWKVKNA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.845 kDa
Sequence
MTQITLLTPDDWHLHFRDGDMLQETVPATARLFQRAIVMPNLLPPVTDAKMVTEYRERILAARPAGSTFEPLMTIFLTNNTTEQDIIDAKAAGVVAAKLYPAGATTNSDAAVKALDALFPVFEAMAKHGMLLLVHGEVTESHIDIFDREAMFIERYLARIVAAFPTLKVVFEHITTKDAADFVMSAADNVAATITPQHLLLNRNDLLVGGVRPHNFCLPVLKRSTHQEALRAAVATGSSKFFLGTDSAPHEKHRKESACGCAGCYSAWSALELYAQVFDDLGALDKLEGFASKHGPDFYGLPRNTSTVTLVKEKWTVPSEIILPNGNPIVPFFAGEEINWKVKTA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella piezotolerans (strain WP3 / JCM 13877)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.649 kDa
Sequence
MTQLTIITPDDWHLHFRDGDMLQETVPATARLFNRAIVMPNLLPPVTDAKLASAYRERILAARPAGSTFEPLMTIFLTNNTTEQDIIDAKAAGVVAAKLYPAGATTNSDAAVKALDALFPIFEAMEKHGLLLLVHGEVTESHIDIFDREALFIERYLARIVNAFPGLKVVFEHITTKDAADFVMSAADNVAATITPQHLLLNRNDLLVGGVRPHNFCLPVLKRSTHQEALRAVVATGSSKFFLGTDSAPHEKHRKESACGCAGCYSAWSALELYAQVFDDLGALDKLEGFASIHGPDFYGLPRNTGSVTLVKETWTVPSEIILPNGNPIVPFFAGEEVSWKVKTA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Nitrosomonas eutropha (strain DSM 101675 / C91)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.476 kDa
Sequence
MTNKLTFTRPDDWHLHLRDGKAMQSVLPDTARRFARAMIMPNLKLPVVTTEQAAAYRARILSALPQELVGQFEPLMTLYLTDTTTPEEISRAKASGIVQAVKLYPAGATTHSDAGVTDIDRCKATLAMMEKLDMPLLVHGEVVDPAVDIFDREKIFIDRVLIPLLQRFPGLRVVFEHITTREAVEFVQSISNRIAATITAHHLMLNRNALFTGGLQPHHYCLPVLKREIHRQALVAAATSGHSRFFLGTDSAPHPLKDKESACGCAGIYSAHAAIEFYAEIFEQAGRLDRLEAFASFYGPDFYGLPRNTDQISLSKESWQIPGEVEFGGDRLVPLRAGEQVCWRL
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / NCIMB 11848 / C-107)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.245 kDa
Sequence
MVTTLQLTRPDDWHLHLRDGKMLTDIVPATGRRFARAIIMPNLRPPITTTTQALAYRKRILAAQPKNLDFEPLMTLYLTDNTIPEEITRARDSGHIYAVKLYPAGATTNADFGVTCLHKLYPVLEALQQQQLPLLIHGEVTDPAVDIFDRERVFIESHLIPLLHDFPALRVVLEHITTQEAVDFIEAAPPNIAATITPHHLLFNRNALLAGGIQPHYYCLPVLKREIHRQALVAAATSGNPKFFLGTDSAPHAKTAKETACGCAGIYSSHAALELYAEAFEEASALEKLEAFASFHGPDFYGLPRNQDTVTLIKTPWQVPESLPYGDDALIPLRGGTTVAWRLAE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Acaryochloris marina (strain MBIC 11017)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.498 kDa
Sequence
MQKLTLTRPDDWHLHLRDGDALKAVLPHSARQFARAIVMPNLKPPVRTVADAADYRNRILAALPVGQTFEPLMTLYLTDNTSPEEISAAKASKFVKAVKYYPAGATTNSDFGVTDIRKCDRIFAAMEQEDIPLLLHGEVTDTNIDVFDREKVFIETHLIPLVSRFPKLRVVLEHITTSEAVTFVLNTNENIGATITPQHLLFSRNAIFKGGIRPHYYCLPILKREKHRQALLQAATSGNPKFFLGTDSAPHARNSKEQSCGCAGCYSALHAMELYAEAFESANALDKLEAFASFYGPDFYQLPRNTKTITLAKQTWQIPDEVPFPGTGLVPLRAGEEITWKIMDG
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Agrobacterium fabrum (strain C58 / ATCC 33970)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.95 kDa
Sequence
MKSLTLRRPDDWHLHLRDGAMLEGVIGDTSRHFARAIIMPNLVPPVVTTADASAYRERILKAIPEGDRFEPLMTLYLTEDTVADDVEEGKKSGLITAVKLYPAGATTNSHGGVRDFNKAMPVLERMAKIGLPLCVHGEVTTPDVDIFDREKAFIDTVLEPLRQRLPELKVTMEHITTRDGVDYIKSSNANLAGSITTHHLIINRNAILVGGIKPHYYCLPVAKREEHRLALRAAATSGDARFFLGTDSAPHVDPLKECACGCAGIYTSINTMSCLAHVFEDENALDKLEAFASLNGPAWYGLAPNDETITLVKREEAVAFPEKIETGAGPVTVFDPMFPLHWDVN
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Methylobacillus flagellatus (strain KT / ATCC 51484 / DSM 6875)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.72 kDa
Sequence
MTTTITITRPDDWHLHLRDGAALSAVLPDSARRFGRAIVMPNLRPPVTTTALAYAYRERIMQAMPAGSGFEPLMTLYLTDNTSAEEIDRAKASGIVHGVKLYPAGATTNSDSGVTNIGHCVKALEAMEKHGIPLLVHAEVTDVDVDVFDRERVFIERNMVPLLERFQGLRVVFEHITTKDAANFVAGAPENVAATITAHHLLMNRNAMFNGGIRPHHYCLPVLKREEHRLALVAAATSGNPKFFLGTDSAPHAKSAKEAACGCAGMYTAHAGIELYTEVFDAAGSLDRLEAFASFHGPDFYRLPRNTDKITLEKTAWEVPASLPFAGDELVPLRAGSHISWRLKD
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Hahella chejuensis (strain KCTC 2396)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.661 kDa
Sequence
MSDLVITRPDDWHLHLRDGDALATTVPATARLFSRAIVMPNLVPPVTHTAQAEAYRHRILSHVPAGAAFDPLMTLYLTNNTSPEEIVAARQSGIVYGCKLYPAGATTNSDAGVTDVANVFSVLEKMSDMGMPLLIHGEVVQADVDIFDREKRFIDETLTPLTERFPNLKIVLEHITTRDAVEFVNQAGSNVGATITAHHLLYNRNHMLVGGIRPHFYCLPILKRSEHQLALRDAAASGSDRFFLGTDSAPHPKEKKEAACGCAGCFTAPSALELYAEAFDELGALDKLEGFASLHGPTFYGLPINSGKVRLSKQEWTMPASMALGDSSIVPFRAGETIRWKAELL
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Halorhodospira halophila (strain DSM 244 / SL1)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.158 kDa
Sequence
MDTLTLPRPDDWHLHLRDGALMQAVAPQAAAVFSRAIIMPNLQPPVTTVEQAAAYRQRILGALPAGSTFEPLMTLYLTDKTSPEEIVRAAASGFVHAVKLYPAGATTHSDAGVTDLLLCYDALAAMEEQGLPLLIHGERTGPELDIFERETAFIDDVLQPLLDRHPRLKVVLEHVTTAVGAELVTGDDPRLAGTFTPQHLLYNRNDLLVGGLKPHYYCMPILKREADREALLEAATSGHPRVFLGTDSAPHPRGAKESACGCAGCYTAPIALSLYAEAFEAAGALERLADFAGRNGPAFYGLPVNPETVTLERAPLEVPASYPGGDEPVVPLRAGESLAWRLHQP
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Sinorhizobium fredii (strain NBRC 101917 / NGR234)
Length
345 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.852 kDa
Sequence
MQELVIRRPDDWHLHLRDGGVLRGVIGDTSRHFARAIVMPNLVPPVVTSADAAAYRQRILAAIPAGDRFEPLMTLYLTEGTDPDDVEAGYGSGLVKAVKLYPAGATTNSHSGVRDIAKAMPVLERMAEIGMPLCVHGEVTTPEVDIFDREAVFIETVLDPLRRRLPDLRITMEHVTTKDGVDYIKEHAGNLAGSITTHHLIINRNAILVGGIKPHYYCLPVAKRERHRQALRAAAVSGDVRFFLGTDSAPHVDPLKECACGCAGIYTSVNTMSCLAHVFEEEGALDRLEAFTSLNGPAWYGLPANEETITLRKANEPVRYPAKIETEAGLITVFDPLFPLYWAVA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Erythrobacter litoralis (strain HTCC2594)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.576 kDa
Sequence
MTETLTIRRPDDWHLHFRDGAMMRGVVPYTARQFARAIVMPNLTPPVTTTALGAAYRERILAAVPEGVDFRPLMTAYLTDETDADDLIDGYTHGVFTAAKLYPANATTNSASGVTDVEALYPVFERMAAAGMVLCIHGEVTDADVDVFDREKEFIERTMAPLHAAIPALKIAFEHITTSDAVDFVVGANDNIGATITPQHLHINRNAMLVGGIQPHNYCLPVAKRETHRLALRQAATSGPPKFFLGTDSAPHEKHTKESACGCAGIFGAPYALESYLAVFEEEDALDKFEAFASLNGPAFYGLPVNDETITLERVPHNVPDSLETEGGKVVPFHAGQELNWRLK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Leptothrix cholodnii (strain ATCC 51168 / LMG 8142 / SP-6)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.312 kDa
Sequence
MTTTLTLIRPDDWHLHVRDGAALAAVVPHTARQFARAIIMPNLRPPVTTAAQAVAYRERIAAAVPAGVDFTPLMTLYLTDNTPADEIVRAQAAGVVALKLYPAGATTNSDAGVTDVRKTYAALEAMQRAGMPLLVHGEVTDPAVDVFDREAVFIDQVMRPLRRDFPELKVVFEHITTQEAADYVAEADAHTAATITAHHLLYNRNAIFTGGLRPHYYCLPVLKREVHRLALVKAATSGSSKFFLGTDSAPHPAHLKEHAAACAGCYTALSAIELYAQAFDDAGALDKLEGFASLHGPDFYGLPRNSGTLTLRREPWQLPETLAFGDAQLKPLCGGETLDWRLLA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Cupriavidus necator (strain JMP 134 / LMG 1197)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.509 kDa
Sequence
MTQKLTITRPDDWHLHLRDGAALAAVLPDTARQFGRAIIMPNLKPPVTTVEQAQAYRARILAALPAGMSFEPLMTLYLTDNTPAEEIVAAKASGFVHGVKLYPAGATTNSDAGVTDIRRCAGALEAMQRVGLPLLVHGEVTDGDIDIFDREAVFIDRVMTPLRRDFPELKVVFEHITTRDAAQYVRDASGPVGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETHREALVAAATSGSDRFFLGTDSAPHARGLKEHACGCAGCYTALHAMELYAEAFDAAGALDKLEAFASFNGPAFYGLPRNTGTLTLEREDWQLPAELPYGDATLVPLRAGETLRWKAR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.579 kDa
Sequence
MTQKLTITRPDDWHLHLRDGAALAAVLPDTARQFARAIVMPNLKPPVTTVAQAQAYRARILAALPAGMQFEPLMTLYLTDNTGPEEIAAARASGFVHGVKLYPAGATTNSDAGVTDIRRCYPALEAMQRAGLPLLVHGEVTDPAIDIFDREAVFIERVMTPLRRDMPELKVVFEHITTKDAAQYVRDASGPVGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETHREALVAAATSGSERFFLGTDSAPHARGLKEHACGCAGCYTALHAMELYAEAFDAAGALDKLEAFASFNGPAFYGLPRNTGTLTLEREDWELPAELPYGDTTLVPLRGGETLRWKAR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.849 kDa
Sequence
MMSLTITRPDDWHVHLRDGIQLNDTVRDISRYMGRAIIMPNLMPPATCTDTALAYRERIVAAKTPDNQFEPLMVLYLTDNTSPDEIRKAKATGLIHAAKLYPAGATTNSDSGVTSISNLYPVLEAMAEVGMLLLVHGEVTDSSIDIFDREKVFLETILAQVVTDFPKLKIVLEHITTSDAVEFVNKAPDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALIAAATSGSKKFFLGTDSAPHLKDKKEASCGCAGSYTAHAAIELYAEAFEAAGALDKLEAFASFYGADFYGLPRNTDTITLEKTPWQVPDSYPLANDRVVPIRAGEMLDWQVIS
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella sediminis (strain HAW-EB3)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.011 kDa
Sequence
MTQITLLTPDDWHLHFRDGDMLKETVPATARLFQRAIVMPNLLPPVTDAKMVIEYRERILAARPEGSDFEPLMTLFLTNDTTEQDIIDAKAAGVVAAKLYPAGATTNSDAAVKALDALFPIFEKMAEVGMLLLVHGEVTESHIDIFDREALFIERNLRRIVDAFPTLKVVFEHITTKEAADFVMSASDNVAATITPQHLLLNRNDLLVGGVRPHNFCLPVLKRNIHQEALRAAIATGSSKFFLGTDSAPHEKHRKESACGCAGCYSAWSALELYAQVFDDLGIIDKLEGFASIHGPDFYGLPRNTSTVTLVKEKWTVPSEIILPNGNPIVPFFAGEEVSWKVKS
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella woodyi (strain ATCC 51908 / MS32)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.682 kDa
Sequence
MTQITLLTPDDWHLHFRDGDMLQETVPATARLFQRAIVMPNLLPPVTDAKLASAYRERILAARPEGSSFEPLMTIFLTNDTSKQDIIDAKAAGVVAAKLYPAGATTNSDAAVKGLDALFPIFETMAEIGMLLLVHGEVTESHIDIFDREALFIERNLSRIVDAFPQLKVVFEHITTKEAAEFVTSASDNVAATITPQHLLLNRNDLLVGGVRPHNFCLPVLKRNIHQEALRAAVATGSSKFFLGTDSAPHEKHRKESACGCAGCYSAWSALELYAQVFDDLGVIEKLEGFASTHGPDFYGLPRNTGTVTLVKESWTVPSEIILPNGNPIVPFFAGEEVNWKVKS
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.068 kDa
Sequence
MQTLTIIRPDDMHLHLRDGDALKAVAPYTARQMGRAVIMPNLKPPVVSVADALAYKARIMAALPEGSAFEPLMTLYLTDQATPELVREAKAAGIVAFKLYPAGATTNSDSGVTDLFKLIPVLEEMAKQGILFLVHGEVTDPEIDIFDREAAFIGRVMKPVLAQVPNLKVVFEHITTAEAARLVLEAGDNVAATVTPQHLLLNRNDLLVGGVRPHHFCLPVLKRETHRQALVAAVTGEKAHKFFLGTDSAPHAKSAKENACGCAGMFSAMTAIELYAEVFEKAGALDKLEAFASKNGARFYGIPENADTITLVKQSQTVPASVPYGDGELVPMRAGGEIGWTVQY
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Neisseria gonorrhoeae (strain NCCP11945)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.055 kDa
Sequence
MQTLTIIRPDDMHLHLRDGDALKAVAPYTARQMGRAVIMPNLKPPVVSVADALAYKARIMAALPEGSAFEPLMTLYLTDQATPELVREAKAAGIVAFKLYPAGATTNSDSGVTDLFKLIPVLEEMAKQGILFLVHGEVTDPEIDIFDREAAFIGRVMKPVLAQVPNLKVVFEHITTAEAARLVLEAGDNVAASVTPQHLLLNRNDLLVGGVRPHHFCLPVLKRETHRQALVAAVTGEKAHKFFLGTDSAPHAKSAKENACGCAGMFSAMTAIELYAEVFEKAGALDKLEAFASENGARFYGIPENADTITLVKQSQTVPASVPYGDGELVPMRAGGEIGWTVQY
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Neisseria meningitidis serogroup C (strain 053442)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37 kDa
Sequence
MQTLTIIRPDDMHLHLRDGDALKAVVPYTARQMGRAVIMPNLKPPVVSVADALAYKARIMAALPEGSAFEPLMTLYLTDNATSELVREAKAAGIVAFKLYPAGATTNSDSGVTDLFKLIPVLEEMAKQGILFLVHGEVTDPEIDIFDREAAFIGRVMKPVLAQVPNLKVVFEHITTAEAARLVLEAGDNVAATVTPQHLLLNRNDLLVGGVRPHHFCLPVLKRETHRQALVAAVTGEKAHKFFLGTDSAPHAKSAKENACGCAGMFSAMTAVELYAEVFEKAGALDKLEAFASKNGARFYGIPENAGTITLVKQSQTVPASVPYGDGELVPMRAGGEIGWTVQY
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.054 kDa
Sequence
MQTLTIIRPDDMHLHLRDGDALKAVAPYTARQMGRAVIMPNLKPPVVSVADALAYKARIMAALPEGSAFEPLMTLYLTDQATPALVREAKAAGIVAFKLYPAGATTNSDSGVTDLFKLIPVLEEMAKQGILFLVHGEVTDPEIDIFDREAAFIGRVMKPVLAQVPNLKVVFEHITTAEAARLVLEAGDNVAATVTPQHLLLNRNDLLVGGVRPHHFCLPVLKRETHRQALVAAVTGEKAHKFFLGTDSAPHAKSAKENACGCAGMFSAMTAIELYAEVFEKAGALDKLEAFASKNGARFYGIPENTDTITLVKQSQTVPASIPYGDGELVPMRAGGEIGWTVQY
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Neisseria meningitidis serogroup B (strain MC58)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.084 kDa
Sequence
MQTLTIIRPDDMHLHLRDGDALKAVAPYTARQMGRAVIMPNLKPPVVSVADALAYKARIMAALPEGSAFEPLMTLYLTDNATPELVREAKAAGIVAFKLYPAGATTNSDSGVTDLFKLIPVLEEMAKQGILFLVHGEVTDPEIDIFDREAAFIGRVMKPVLAQVPNLKVVFEHITTAEAARLVLEAGDNVAATVTPQHLLLNRNDLLVGGVRPHHFCLPVLKRETHRQALVAAVTGEKAHKFFLGTDSAPHAKSAKENACGCAGMFSAMTAIELYAEVFEKAGALDKLEAFASKNGARFYGIPENTDTITLVKQSQTVPASVPYGDGELVPMRAGGEIGWTVQY
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.258 kDa
Sequence
MQTLTIIRPDDMHLHLRDGDALKAVVPYTARQMGRAVIMPNLKPPVVSVADALAYKARIMAALPEGSAFEPLMTLYLTDQATPELVREAKAAGIVAFKLYPAGATTNSDSGVTDLFKLIPVLEEMAKQDILFLVHGEVTDPEIDIFDREAAFIERVMKPVLAQVPNLKVVFEHITTAEAARLVLEAGDNVAASVTPQHLLLNRNDLLVGGVRPHHFCLPVLKRETHRQALVAAVTGEKAHKFFLGTDSAPHAKSAKENACGCAGMFSAMTAVELYAEVFEKAGALDKLEAFASKNGARFYGIPENTDTITLVKQSQTVPASVPYGDGELVPMRAGGEIGWMVQY
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Ralstonia pickettii (strain 12J)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.76 kDa
Sequence
MTDTLTIVRPDDWHLHLRDGDALADVVGDTARQFGRAIIMPNLKPPVTTTAQARAYRERILAALPAGTQFEPLMTLYLTDNTSPEVIREARASGFIHGVKLYPAGATTNSDAGVTDLRRCAKTLEAMQEVGMPLLVHGEVTDPTVDIFDREAVFIDTVMLPLRRDFPALKVVFEHITTKHAAEYVRDAEGPVGATITAHHLLYNRNALFVGGIRPHYYCLPVLKRETHRLALVAAATSGHPRFFLGTDSAPHAKGVKEHACGCAGCYTALHAMELYAEAFEDANALDKLEGFASLHGPDFYGLPRNAGTLTLTRSQWQLPAEVPFGEQTLVPLRGGEMLRWKSV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Ralstonia solanacearum (strain GMI1000)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.816 kDa
Sequence
MIDTLTIVRPDDWHLHLRDGDALADVVGDTARQFGRAIIMPNLKPPVTTTAQARAYRERILAALPAGTRFEPLMTLYLTDNTTPEEVRAARASGFVHGVKLYPAGATTNSDAGVTDLRRCAKTLEAMQDVGMPLLVHGEVTDPTVDIFDREAVFIDTVMQPLRRDFPALKVVFEHITTKHAAEYVRDAQGPVGATITAHHLLYNRNALFVGGIRPHYYCLPVLKRETHRLALVAAATSGHPRFFLGTDSAPHAKGLKEHACGCAGCYTALHAMELYAEAFEDANALDKLEGFASLHGPDFYGLPRNAGTLTLTRSQWQLPAEVPFGEQMLVPLRGGEMLRWKTV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Roseobacter denitrificans (strain ATCC 33942 / OCh 114)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.565 kDa
Sequence
MTKTLTIRRPDDWHLHLRDGAMLRAVLPETTAHFARAIIMPNLVPPVVTFAQAQDYHARILAALPEGAEFTPLMTLYLTEDTDPDDVAAAHANGLVHAVKLYPAGATTNSASGVANFDNIRAVLERMAEIGLPLCVHGEVTDDDIDIFDREAVFIDRVLDPIRQATPGLRVVMEHITTRNAVDYATAQDDTLGATITTHHLVINRNHILAGGIKPHYYCLPVAKREEHRLALRAAATSGDARFFLGTDSAPHTDANKLLPCGCAGCFTATNTMSILAHVFEEEQALERLEGFASLHGPAFYRLPANEARLTLTKTPATFPSHIETEDGPVTVFDPGFVPNWTVV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.867 kDa
Sequence
MDTITLLQPDDWHAHLRDGLALKRTVPDLAQQFARAICMPNLVPPVKTVDEAEAYRERIMAHVPEGVHFDPRMVLYFTDHTSPSEVKKIKDSAHVNAIKLYPAGATTNSDNGVSDIRKVYAVIEQLEEHQVPLLLHGEVTHHHVDIFDREKRFLDEVLSPLLKQFPKLKLVLEHITTSEAAHFVLEQDRNVAATITPQHLLFNRNDMLVGGIKPHFYCLPILKRQTHQQTLIEVATSGNPKFFLGTDSAPHSKNAKENACGCAGCYSAPTAIELYAQAFDQVNKIERLEGFASHFGADFYGLPRNTNTITLVKEDQIIPEQLDYLDDEKIIPLYAGKTIQWRKV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Acinetobacter baumannii (strain AB307-0294)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.724 kDa
Sequence
MNSITLLQPDDWHAHLRDGLALKRTVPDLAKQFARAICMPNLVPPVKTVEEALAYRERILAHVPEGNNFDPRMVLYFTDHTSPDEVRKIKESEHVNAIKLYPAGATTNSDNGVSDIRKVYAVIEQLEEHQVPLLLHGEVTHNHVDIFDREKRFLDEVLSPLLKQFPKLKVVLEHITTSDAAHFVLEQDRNVAATITPQHLLFNRNDMLVGGIKPHFYCLPILKRQTHQTTLLEVATSGNPKFFLGTDSAPHAQNAKENACGCAGCYSAPNAIELYAQAFDQVGKLERLEGFASHFGADFYGLPRNTSTITLVKEDNLVPESFDYLDNQKIIPLHAGKTLQWRKV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Acinetobacter baumannii (strain AB0057)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.724 kDa
Sequence
MNSITLLQPDDWHAHLRDGLALKRTVPDLAKQFARAICMPNLVPPVKTVEEALAYRERILAHVPEGNNFDPRMVLYFTDHTSPDEVRKIKESEHVNAIKLYPAGATTNSDNGVSDIRKVYAVIEQLEEHQVPLLLHGEVTHNHVDIFDREKRFLDEVLSPLLKQFPKLKVVLEHITTSDAAHFVLEQDRNVAATITPQHLLFNRNDMLVGGIKPHFYCLPILKRQTHQTTLLEVATSGNPKFFLGTDSAPHAQNAKENACGCAGCYSAPNAIELYAQAFDQVGKLERLEGFASHFGADFYGLPRNTSTITLVKEDNLVPESFDYLDNQKIIPLHAGKTLQWRKV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Acinetobacter baumannii (strain ACICU)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.724 kDa
Sequence
MNSITLLQPDDWHAHLRDGLALKRTVPDLAKQFARAICMPNLVPPVKTVEEALAYRERILAHVPEGNNFDPRMVLYFTDHTSPDEVRKIKESEHVNAIKLYPAGATTNSDNGVSDIRKVYAVIEQLEEHQVPLLLHGEVTHNHVDIFDREKRFLDEVLSPLLKQFPKLKVVLEHITTSDAAHFVLEQDRNVAATITPQHLLFNRNDMLVGGIKPHFYCLPILKRQTHQTTLLEVATSGNPKFFLGTDSAPHAQNAKENACGCAGCYSAPNAIELYAQAFDQVGKLERLEGFASHFGADFYGLPRNTSTITLVKEDNLVPESFDYLDNQKIIPLHAGKTLQWRKV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Acinetobacter baumannii (strain SDF)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.749 kDa
Sequence
MNSITLLQPDDWHAHLRDGLALKRTVPDLAKQFARAICMPNLVPPVKTVEEALAYRERILAHVPEGNNFDPRMVLYFTDHTSPDEVRKIKESEHVNAIKLYPAGATTNSNNGVSDIRKVYAVIEQLEEHQVPLLLHGEVTHNHVDIFDREKRFLDEVLSPLLKQFPKLKVVLEHITTSDAAHFVLEQDRNVAATITPQHLLFNRNDMLVGGIKPYFYCLPILKRQTHQTTLLEVATSGNPKFFLGTDSAPHAQNAKENACGCAGCYSAPNAIELYAQAFDQVGKLERLEGFASHFGADFYGLPRNTSTITLVKEDNLVPESFDYLDNQKIIPLHAGKTLQWRKV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.724 kDa
Sequence
MNSITLLQPDDWHAHLRDGLALKRTVPDLAKQFARAICMPNLVPPVKTVEEALAYRERILAHVPEGNNFDPRMVLYFTDHTSPDEVRKIKESEHVNAIKLYPAGATTNSDNGVSDIRKVYAVIEQLEEHQVPLLLHGEVTHNHVDIFDREKRFLDEVLSPLLKQFPKLKVVLEHITTSDAAHFVLEQDRNVAATITPQHLLFNRNDMLVGGIKPHFYCLPILKRQTHQTTLLEVATSGNPKFFLGTDSAPHAQNAKENACGCAGCYSAPNAIELYAQAFDQVGKLERLEGFASHFGADFYGLPRNTSTITLVKEDNLVPESFDYLDNQKIIPLHAGKTLQWRKV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Acinetobacter baumannii (strain AYE)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.724 kDa
Sequence
MNSITLLQPDDWHAHLRDGLALKRTVPDLAKQFARAICMPNLVPPVKTVEEALAYRERILAHVPEGNNFDPRMVLYFTDHTSPDEVRKIKESEHVNAIKLYPAGATTNSDNGVSDIRKVYAVIEQLEEHQVPLLLHGEVTHNHVDIFDREKRFLDEVLSPLLKQFPKLKVVLEHITTSDAAHFVLEQDRNVAATITPQHLLFNRNDMLVGGIKPHFYCLPILKRQTHQTTLLEVATSGNPKFFLGTDSAPHAQNAKENACGCAGCYSAPNAIELYAQAFDQVGKLERLEGFASHFGADFYGLPRNTSTITLVKEDNLVPESFDYLDNQKIIPLHAGKTLQWRKV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.816 kDa
Sequence
MQQITLTQPDDWHLHFRDNDMLLETVPATARTFKRAIVMPNLVPPVVNAELASAYRDRILAARPQGSEFEPLMTLFLTNTTSIDDIRAAKKAGVVAAKLYPAGATTNSDAAVKGIEALFPVFAEMAEQGMLLLIHGEVTESHVDIFDREKLFIEQFLVKIVNQFPQLKVVLEHITTSDAVDFVSASSHNVAATITPQHLLLNRNDLLVGGVRPHNFCLPVLKRSTHQQALRKAVATGSSKFFLGTDSAPHEKSAKESACGCAGCYSAWSALELYAQVFEELDALDKLEGFASHHGADFYGLPRNTKQVTLVKEEWTIPEVITLPNGEPIVPFFAGQTVNWALKA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Microcystis aeruginosa (strain NIES-843)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.398 kDa
Sequence
MRRLTMTRPDDWHLHLRDGAAMKAVLPHTVRQFARAIIMPNLKPPVRSVADAASYRERILAAVPEGQQFEPLMTLYLTDNTSPEEIVAAKASQFVKAVKYYPAGATTNSDLGVTDLRRCDGVLAAMEQVDMPLLLHGEVTDGDIDVFDREKVFIEKHLIPLITRFPKLRVVFEHITTADAVKFVLSANNNVAATITPQHLLFSRNILFTGGIRPHFYCLPILKREDHRLALLQAATSGNPKFFLGTDSAPHSRYSKESSCGCAGCYSALHALELYAEAFESVDAIDQLEGFASFHGPDFYQLPRNTEQITLTKSPWRIPDELPFPESGLVPLRAGEEITWQLGE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.656 kDa
Sequence
MQSLTIPRPDDWHLHLRDGAMLQTTVPATAAVFHRAVVMPNLVPPVTTVAAAMEYRERILAEIPAGMSFNPLMALYLTADTTPAEIAEAAANEHVIGFKLYPSGATTNSAAGVKSVEALAPVLAAMQEHQVPLLVHGEVTDSDIDIFDRERVFIERHLIPITERFPQLKLVLEHITTADAVKFVENANSNVAATMTPQHLLMNRNDLLVGGIRPHNYCLPILKRRSHQQALQQAALSGNPKFFLGTDSAPHVQANKETACGCAGCYSAPAAIELYAEFFSQHNALDKLANFASVFGADFYQLPRNTETIELVQQPWTVAETVDTATGPMVPYWAGSDLQWKLRG
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Teredinibacter turnerae (strain ATCC 39867 / T7901)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.497 kDa
Sequence
MTDSLTLLRPDDWHIHLRDGTALETTVPHAAASFARAIIMPNLVPPVTNAEEALAYRARIEAQIPAETPFEPLMVLYLTNNTTPETIAAAKAAGVVACKLYPAGATTNSASGVTDIQHIYPALEEMERQGVLLLLHGEVTDSAIDIFDREAVFIERTLRKVVADFPKLKIVLEHITTQQAAEFVAQAPDNVAATITAHHLLYNRNHMLAGGIRPHYYCLPILKRQTHQQALVAAATSGSPKFFLGTDSAPHAKSRKEAACGCAGSYTAFAAIELYAEAFEDAGALDRLEGFASHFGPDFYGLPRNSDTITLRREPWSVPDTLTFGDESLVPVKAGETLNWRVQK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.551 kDa
Sequence
MTQKLTITRPDDWHLHLRDGAALAAVLPDTARQFARAIIMPNLKPPVTTVDQASAYRARILAALPAGMAFEPLMTLYLTDNTPPEEIVAARASGFVHGVKLYPAGATTNSDAGVTDIRRCAATLEAMQREGVPLLVHGEVTDGDIDIFDREAVFIDRVMKPLRRDFPELKVVFEHITTRDAAQYVAEAEGPVGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKREIHREALVKAATSGSPRFFLGTDSAPHARGLKEHACGCAGCYTALHAMELYAEAFDAAGALDKLEAFSSFNGPAFYGLPRNSGTLTLTREDWELPAELPYGDTTLVPLRAGETLRWKAS
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.534 kDa
Sequence
MTQKLTITRPDDWHLHLRDGAALAAVLPDTARQFARAIIMPNLKPPVTTVAQAQAYRARILAALPAGLQFEPLMTLYLTDNTTAEEIAAAKASGFVHGVKLYPAGATTNSDAGVTDIRRCYPALEAMQRAGLPLLVHGEVTDPSIDIFDREAVFIDRVMTPLRRDMPELKVVFEHITTKDAAEYVRDASGPVGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETHREALVAAAVSGSPRFFLGTDSAPHARGLKEHACGCAGCYTALHAMELYAEAFDAAGALDKLEAFASFNGPAFYGLPRNTGTLTLEREDWELPAELPYGDTTLVPLRGGETLRWKAR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.001 kDa
Sequence
MTDSLTIARPDDWHLHFRDGDLLAETVPATANVFGRAIVMPNLTPPVNTVAEAAEYRERILAQVPAGVNFEPLMVLYLTDSTPVQEVERAANSDFVHALKLYPAGATTNSDSGVTDPGKITHLYEAMEKHDVPLLVHGEVTDAEVDIFDRERVFIDRYLADIRDQFPALRIVFEHVTTAEGVNFVREANALTAATVTPQHLLMNRNDLLVGGVRPHNYCLPILKRRQHQEAIQKAVIEGNSRFFLGTDSAPHARTKKEAACGCAGCYSARAALPLYATFLEQHNALDKLEGFASHFGADFYRLPRHTDTVTLVRKPWAVPTVIDAAGEPVVPFFAGEQLPWSLG
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Aromatoleum aromaticum (strain EbN1)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.31 kDa
Sequence
MQTISLIRPDDWHLHVRDGAALATVVPHTARRFGRALIMPNLRPPVTTAAQALEYRARILAAVPPGQHFEPLMSLYLTDNTSPDEIDRAKASGAVVAVKLYPAGATTNSDAGVTAIEKVHAVLERMEKLGMVLCVHGEVTHGDVDVFDREQVFIEQVLAPLVARFPALRVVFEHITTAEAARFVQDAGPNVAATVTAHHLLLNRNAIFAGGIRPHHYCLPVLKRETHRRALVEAATSGNAKFFLGTDSAPHSRAAKETACGCAGCYTAHAAIELYAEAFEQAGALDRLEAFASLNGPAFYGLAPNAERITLAKDAWEVPGEYEYLHDDPLVPLRAGETVAWRVL
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Azoarcus sp. (strain BH72)
Length
344 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.002 kDa
Sequence
MQSITFTRPDDWHLHVRDGAALAAVVPHTAERFGRALIMPNLRPPVTTTAQALAYRDRIRAAVPAGLAFEPLMSLYLTDNTAPDEIERARASGAVIAAKLYPAGATTNSDAGVTAIDKIYPVLERMEACGLVLCVHGEVTGGEVDVFDRERVFMEKILSPLVRRFPALKVVFEHITTAEAAQFVRAAGANVAATVTAHHLLLNRNAIFAGGIRPHHYCLPVLKRETHRVALVEAVTSGNPRFFLGTDSAPHARSTKEAACGCAGCYTAHAGIELYAEVFDAAGALERLEAFASLNGPAFYGLAPNADKITLVRESWSVPAGFPYLDDDPLVPLRAGESVGWRLA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella oneidensis (strain MR-1)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.851 kDa
Sequence
MKTLTITRPDDWHIHLRDGAQLTDTVRDISRYMGRAIVMPNLVPPAIDTETALAYYDRIKARVPAGSQFEPLMVLYLTDKTSPDEIRKAKASGKVFAAKLYPAGATTNSDSGVTDLKNIYPALEAMQEVGMLFLVHGEVTDSSIDIFDRERVFIENILSKIVTDFPNLKIVLEHITTKDAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLAAAASGNKKFFLGTDSAPHAKDRKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNSDTITLVKKAWDIPASYPLGDTNVVPIRAGEQIDWQVE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.63 kDa
Sequence
MTTITITRPDDWHIHLRDGAQLKDTVRDISRYMGRAIVMPNLVPPAIDTETALAYYDRIKAQVPAGSQFEPLMVLYLTDKTSPDEIRKAKASGKIVAAKLYPAGATTNSDSGVTDVKNIYPVLQAMQEVGMLFLVHGEVTDSAIDIFDRERVFIENILSKIVADFPALKIVLEHITTKDAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLGAAASGNKKFFLGTDSAPHAKDKKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNSDTITLVKKSWDVPATYPLGDTNVVPIRAGEAIDWQVE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella sp. (strain ANA-3)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.816 kDa
Sequence
MTTLTITRPDDWHIHLRDGAQLKDTVRDISRYMGRAIVMPNLVPPAIDTETALAYYDRIKAQVPAGSQFEPLMVLYLTDKTSPEEIRKAKASGKIVAAKLYPAGATTNSDSGVTDLKNIYPALEAMQEVGMLFLVHGEVTDSSIDIFDRERVFIENILSKIVADFPKLKIVLEHITTKDAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLGAAASGNKKFFLGTDSAPHAKDRKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNSDTITLVKKSWDVPVSYPLGDNNVVPIRAGEQIDWQVE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella sp. (strain MR-4)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.816 kDa
Sequence
MTTLTITRPDDWHIHLRDGAQLKDTVRDISRYMGRAIVMPNLVPPAIDTETALAYYDRIKAQVPAGSQFEPLMVLYLTDKTSPEEIRKAKASGKIVAAKLYPAGATTNSDSGVTDLKNIYPALEAMQEVGMLFLVHGEVTDSSIDIFDRERVFIENILSKIVADFPKLKIVLEHITTKDAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLGAAASGNKKFFLGTDSAPHAKDRKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNSDTITLVKKSWDVPVSYPLGDNNVVPIRAGEQIDWQVE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella sp. (strain MR-7)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.816 kDa
Sequence
MTTLTITRPDDWHIHLRDGAQLKDTVRDISRYMGRAIVMPNLVPPAIDTETALAYYDRIKAQVPAGSQFEPLMVLYLTDKTSPEEIRKAKASGKIVAAKLYPAGATTNSDSGVTDLKNIYPALEAMQEVGMLFLVHGEVTDSSIDIFDRERVFIENILSKIVADFPKLKIVLEHITTKDAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLGAAASGNKKFFLGTDSAPHAKDRKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNSDTITLVKKSWDVPVSYPLGDNNVVPIRAGEQIDWQVE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella sp. (strain W3-18-1)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.618 kDa
Sequence
MTTITITRPDDWHIHLRDGAQLKDTVRDISRYMGRAIVMPNLVPPAIDTETALAYYDRIKAQVPAGSQFEPLMVLYLTDKTSPDEIRRAKASGKIVAAKLYPAGATTNSDSGVTDVKNIYPVLQAMQEVGMLFLVHGEVTDSAIDIFDRERVFIENTLSKIVADFPALKIVLEHITTKNAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLGAAASGSKKFFLGTDSAPHAKDKKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNSDTITLVKKSWDVPATYPLGDTNVVPIRAGEAIDWQVE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Psychromonas ingrahamii (strain 37)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.554 kDa
Sequence
MTTTRTITRPDDWHLHLRDGEVLKDTVRDTSRYMGRAVIMPNLVPPVTNTALALAYQARIFAAQPKAGFKPLMTLYLTDNTSADEIKKAKASGQIYAAKLYPAGATTNSESGVTSVEKIKEALQAMQEVGMLLLIHGEVTASDIDIFDREEIFLQKVLAPIVASYPNLKIVLEHITTANAVDFVNNAGDNVAATITAHHLMFNRNHMLVGGIRPHLYCLPILKRNIHQQALIKAATSGAKKFFLGTDSAPHAVNRKEAACGCAGCYTAHAAIELYAEVFEQAGALDKLEAFASFNGPDFYNLPRNSDTITLEKSAWDVPASMSFGNQQVVPIKANEQMLWKVL
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.291 kDa
Sequence
MTRQITITRPDDWHLHVRDGDILNDVVPATAACFGRAIIMPNLVPPVTDASAAMAYRDRILAAARGTDFQPLMTLYLTESTTAETIREAKAAGVVAAKLYPAGATTNSASGVTDIRNIYPVLEAMADCGMLLLVHGEVTDSDIDIFDREKVFLERVLAPTLTAFPSLRVVLEHITTAESAEFVRNHQGNNLGATLTPQHLMYNRNHMLVGGIRPHLYCLPILKRNKHQEALREAVASGDPRFFLGTDSAPHAKDKKEAACGCAGCYSAYGAIGLYADIFEELGILDKLEAFASFNGADFYGLPRNTDTVTLVREPWTMPENLPLAGGGIVPLKAGETVNWRLA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Marinomonas sp. (strain MWYL1)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.087 kDa
Sequence
MNEITIIKPDDWHLHFRDQDMLLETVAATARCFERAVVMPNLVPPVTTAELALSYKERILAARPAGSTFMPVMTIYLTDKTSVQDIQDAKKAGVLAAKMYPAGATTNSDSGVNSLESLYPVFEALADNGMLLLIHGEVTQKHIDIFDREKEFIDQHMVNIVDRVPNLKVVFEHITTKDAVDFVLAARDGVAATITPQHLLLNRNDMLDGGVRPHNYCLPVLKRSTHQQALREVVKSGSPKFFLGTDSAPHAKHRKESDCGCAGCYSAWSALELYTQVFDELGALDKLEGFASLYGADFYGLPRNTEKVTLVRESWEVPNSITLPNGEPIVPFFAGKQISWKLK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Variovorax paradoxus (strain S110)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.837 kDa
Sequence
MTDTLTITRPDDWHLHVRDGAALEAVVPHSARQFGRALVMPNLRPPVTTAAQAVAYRDRIRAAVPPGTAFEPVMSLYLTDKLPPEEIALAAEAGVRALKLYPAGATTNSDAGVTDIRHTYKTLEAMQKHGLLLLVHGEVTDPAVDLFDREAVFIDRVMIPLRRDFPELKVVFEHLTTQEGAHYVRDANRFTAATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETHRVALVQAATSGSDRFFLGTDSAPHPAHLKEHALGCAGCYTALTAIELYAEAFDSVDALDKLEGFASFHGPDFYGLPRNSGTITLKRESWTVPETVPYGDATLKPLRGGETVHWKLM
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Helicobacter hepaticus (strain ATCC 51449 / 3B1)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.495 kDa
Sequence
MPQTLQLTNPMDMHLHLREGEMLSAILPFSANPFSAAVVMPNLKTPITTTAQALAYKRQILSLCSTSFEPLMSIFLTPDLDKQELIRAKEAGIHILKLYPKGSTTGSEKGVKEMLCEKTLHIFEIAQELGFILSIHGESNGFCMEREYEFLPIFAHIAQHFPRLRIIIEHMSDRRSLELIEQYPNLYATLTLHHITMNLDDVLGGGINPHHFCKPMLKTKKDQQALLQAALNAHPKVSFGSDSAPHLESAKLNSKGAAGIFSAPILLPALAEVFAFHNALDCLQTFISNRAIANYKLKHFPIKTITLERVENPVPPYINTPLGHIIPLRAQTNLSWRIKEENR
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Synechococcus sp. (strain WH8102)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.069 kDa
Sequence
MAEQLTITAPDDWHVHLRDEEMLERVVAYTARCFRRAIVMPNLRPPVTTVDAARSYRDRILSACPEGVAFTPLMTAYLTDNSDPDDLERGFQEGVYTAAKLYPANATTNSAAGVTDLDQIGRVLSRMEAIGMPLLIHGEVTDADVDVFDREAVFIERHLKSLRTRHPELKVVFEHITTEQAVDYVGSSDRNLAATITPHHLQINRNSMFLGGLRSDFYCLPVVKRERHRLALRRAATSGDPRFFLGTDSAPHPRAGKETSCGCAGIFNAPFALESYAQVFAEEEAMHHLEGFASLHGPAFYGLPANNDTVTLEKVAVDVPELVNGLVPFHAGETLPWRLQPCM
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Synechococcus sp. (strain CC9902)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.057 kDa
Sequence
MSDQIQLIAPDDWHVHLRDGEMLKQVVPYTAQMFRRAIVMPNLRPPVVTVEAAKAYRDQIVAACHPNWGFTPLMTAYLTDDIAPEEIERGFHEGVFTAAKLYPANATTNSAAGVTELRHIHGVLLVMERIGMPLLIHGEVTDVDVDVFDREAVFIERSLKPIRDRYPGLKVVLEHITTEQAVDFVGSADQNLAATITPHHLHINRNAMFAGGLRSDFYCLPVAKRERHRLALRRAAMSGDRRFFLGTDSAPHARPGKESSCGCAGIFNAPHALESYAMAFAQDDKLDKLEAFASLHGPAFYGLPVNEGIVTLQRDDKLVPNVVNGLVPFHAGETLPWRLQPCT
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella baltica (strain OS223)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.692 kDa
Sequence
MTTITITRPDDWHIHLRDGAQLKDTVRDISRYMGRAIVMPNLVPPAIDTETALTYYDRIKAQVPAGSQFEPLMVLYLTDKTSPDEIRKAKASGKIVAAKLYPAGATTNSDSGVTDLKNIYPALEAMQEVGMLFLVHGEVTDSSIDIFDRERVFIENILSKIVADFPELKIVLEHITTKDAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLAAAASGSKKFFLGTDSAPHAKDKKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNADTITLVKKSWDVPATYPLGDTNVVPIRAGEAIDWQVE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella baltica (strain OS155 / ATCC BAA-1091)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.715 kDa
Sequence
MTTITITRPDDWHIHLRDGAQLKDTVRDISRYMGRAIVMPNLVPPAIDTETALTYYDRIKAQVPAGSQFEPLMVLYLTDKTSPDEIRKAKASGKIVAAKLYPAGATTNSDSGVTELKNIYPALEAMQEVGMLFLVHGEVTDSSIDIFDRERVFIENILSKIVADFPELKIVLEHITTKDAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLAAAASGSKKFFLGTDSAPHAKDKKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNADTITLVKKPWNVPATYPLGDTNVVPIRAGEAIDWQVE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella baltica (strain OS185)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.758 kDa
Sequence
MTTITITRPDDWHIHLRDGAQLKDTVRDISRYMGRAIVMPNLVPPAIDTETALTYYDRIKAQVPAGSQFEPLMVLYLTDKTSPDEIRRAKASGKIVAAKLYPAGATTNSDSGVTDLKNIYPALEAMQEVGMLFLVHGEVTDSSIDIFDRERVFIENILSKIVADFPELKIVLEHITTKDAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLAAAASGSKKFFLGTDSAPHAKDKKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNADTITLVKKPWDVPATYPLGDTNVVPIRAGEVIDWQVE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella baltica (strain OS195)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.729 kDa
Sequence
MTTITITRPDDWHIHLRDGAQLKDTVRDISRYMGRAIVMPNLVPPAIDTETALTYYDRIKAQVPAGSQFEPLMVLYLTDKTSPDEIRRAKASGKIVAAKLYPAGATTNSDSGVTDLKNIYPALEAMQEVGMLFLVHGEVTDSSIDIFDRERVFIENILSKIVADFPELKIVLEHITTKDAVDFVTQASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLAAAASGSKKFFLGTDSAPHAKDKKEAACGCAGSYTAHAAIELYAEAFESVNALDKLEAFASFNGPDFYNLPRNADTITLVKKPWNVPATYPLGDTNVVPIRAGEAIDWQVE
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1)
Length
343 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.531 kDa
Sequence
MQRITLTRPDDWHLHLRDGEQLATVLPHTATVFGRAIIMPNLKPPVTTVDQAAAYRERILAALPAGAHFEPLMTLYLTDNTPPAEIEKAAASGFVHAVKLYPAGATTNSDAGVTDLARCEETLAAMAERGLPLCVHGEVTRDEVDIFDREAHFIDEVLDPLVQRHSRLRVVFEHITTQAAVDYLRQAPDRVGATLTVQHLMANRNHMLVGGVRPHYYCLPILKRERDRQALVEAATSGHPRFFLGTDSAPHPKGAKESACGCAGVYSAHAALPFYAEIFEAAGALDRLEGFASHHGADFYGLPRNRDSVTLERAATPIPEAFPMGDDTLVPFRAGGEVAWRVV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.267 kDa
Sequence
MTKLTITRPDDWHVHLRDGDVLTDTVRDTGRYMGRAIIMPNLVPPATNVDSALAYYERIKAVCTTNFEPLMVLYLTDNTTAEDIRAAKASGKVVAAKLYPAGATTNSDSGVTDVKNIYPVLEAMQEVGMLFLVHGEVTDSSIDIFDREATFINNTLKQVVADFPSLKIVLEHITTKDAVDFVMGASDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLAAAASGSKKFFLGTDSAPHAKDRKEAACGCAGSYTAHAAIELYAEAFESVGALDKLEAFASFNGPDFYGLPRNTDSITLVKRSWEVPATYPLGDTGVVPIRAGETIDWQVED
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Photobacterium profundum (strain SS9)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.604 kDa
Sequence
MTTITITRPDDWHVHLRDGDVLKDTVRDISRYMGRAIIMPNLIPPVIDTESALSYRERIIAQGPQGNFSPLMVIYLTDNTSAEEIHKAKASGHVYAAKLYPAGATTNSDSGVTSIDHIRPALQAMQEAGMQLLIHGEVTAHDIDIFDREKVFLETVLAPIVEQFPNLRMVLEHITTADAVEFVTNAGPNVGATITAHHLMFNRNHMLVGGIRPHFYCLPILKRNIHQDALVKAATSGNPKFFLGTDSAPHAQGRKESACGCAGSYTAHAAIELYAEVFEAADALDKLEAFSSFNGPDFYNLPRNTDTITLKKESWNVPETMAFGGDEVVPIRAGEAMLWKVI
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Vibrio campbellii (strain ATCC BAA-1116 / BB120)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.798 kDa
Sequence
MTTLTITRPDDWHVHLRDGEVLKDTVRDISRYNGRALIMPNTVPPVTNTEMALAYRDRILAEQHGEQFEPLMALYLTDNTTPDEIRKAKATGKIVAAKLYPAGATTNSDSGVTDAKNIYHVFEAMEEVGMLLLVHGEVTHNHVDIFDREKEFLDTVLAPIVNDFPNLKIVLEHITTSDAANFVNNASDNVAATITAHHLLFNRNHMLVGGIKPHFYCLPILKRNTHQQALIEAATSGSKKFFLGTDSAPHAKGAKESACGCAGSYTAHAALELYAEVFENEGKLENLEAFASLNGPDFYGIARNTDTVTLEKASWDVPETMPFGSDIVVPIRANEKIEWEVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.462 kDa
Sequence
MTTLTITRPDDWHVHLRDGDVLADTVRDISRYNGRALIMPNTVPPVTTTEMALAYRERIMAAQPQAHFEPLMALYLTDNTSPEEIRKAKASGKVVAAKLYPAGATTNSDSGVTSAKNIYPVLQAMQEVGMLLLVHGEVTTHEVDIFDREKTFLDTVLAPIVNDFPQLKIVLEHITTADAVTFVQQAGDNVAATITAHHLLFNRNHMLVGGIRPHFYCLPILKRATHQHALVAAATSGSKKFFLGTDSAPHAKGRKEAACGCAGSYTAHAALELYAEVFEKEGKLENLEAFASFNGPDFYGLPRNQETVTLTKQAWPVAESMPFGSDIVVPIRAGENIEWTVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.829 kDa
Sequence
MTTLTITRPDDWHVHLRDGEVLKDTVRDISRYNGRALIMPNTVPPVTNTEMALAYRDRILKEQHGEQFEPLMALYLTDNTTPEEIRAAKATGKIVAAKLYPAGATTNSDSGVTDAKNIYHVLEAMEEVGMLLLVHGEVTHHHVDIFDREKEFLDTVLAPIVNDFPNLKIVLEHITTADAAQFVNNASDNVAATITAHHLLFNRNHMLVGGIKPHFYCLPILKRNTHQQALIEAATSGSKKFFLGTDSAPHAKGAKESACGCAGSYTAHAALELYAEVFEKEGKLENLEAFASFNGPDFYGIARNADTVTLEKSAWDVPESMPFGNDIVVPIRANEQIEWKVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Vibrio tasmaniensis (strain LGP32)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.599 kDa
Sequence
MTQLTITRPDDWHVHLRDGEVLKDTVRDISRYNGRALIMPNTIPPVTDTEMALAYRERIMAEQPSEQFQPLMALYLTDNTTPDEIRKAKESGAVVAAKLYPAGATTNSDSGVTSAQKIYHVLEAMQEVGMLLLVHGEVTAHDVDIFDREKEFLDTVLAPIVNDFPNLKIVLEHITTADAATFVKNANENVAATITAHHLLYNRNHMLVGGIKPHFYCLPILKRNTHQLALIEAATSGSKKFFLGTDSAPHAKGAKESACGCAGSYTAHAAVELYAEVFDLEGKIENLEAFASHNGPDFYGMPRNADTITLVKEEWNVAETMPFGSDIVVPIRGGETIAWAVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Vibrio vulnificus (strain CMCP6)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.449 kDa
Sequence
MTTLTITRPDDWHVHLRDGEVLADTVRDISRYNGRALIMPNTVPPVTTSEMALAYRDRIQAHNQTEQFSPLMSLYLTDNTTADEVRKAKASGAVVAAKLYPAGATTNSDSGVTDVKKIYPVLQAMQEVGMLLLVHGEVTTHDVDIFDREKTFLDNVLAPIVQDFPDLKIVLEHITTSDAVVFVKNANENVAATITAHHLLYNRNHMLVGGIKPHFYCLPILKRNTHQLALISAATSGNKKFFLGTDSAPHAKGAKESACGCAGSYTAHAAVELYAEVFEQAGKLENLEAFASHNGPDFYGLPRNQDTITLVKDAWPVPASMPFGGDIVVPIRAGENMEWKVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Vibrio vulnificus (strain YJ016)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.477 kDa
Sequence
MTTLTITRPDDWHVHLRDGEVLADTVRDISRYNGRALIMPNTVPPVTTTEMALAYRDRIQAHNQTEQFSPLMSLYLTDNTTADEVRKAKASGAVVAAKLYPAGATTNSDSGVTDVKKIYPVLQAMQEVGMLLLVHGEVTTHDVDIFDREKTFLDNVLAPIVQDFPDLKIVLEHITTSDAVVFVKNANENVAATITAHHLLYNRNHMLVGGIKPHFYCLPILKRNTHQLALISAATSGNKKFFLGTDSAPHAKGAKESACGCAGSYTAHAALELYAEVFEQAGKLENLEAFASHNGPDFYGLPRNQDTITLVKDAWPVPASMPFGGDIVVPIRAGENMEWKVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.127 kDa
Sequence
MEKLTITRPDDWHLHLRDGAALKAVLPHTVRQFARAIVMPNLKPPVRSVADAAAYRERILAAIPAGGQFEPLMTLYLTDNTNPEEIIAAKASQFVKAVKYYPAGATTNSDFGVTDIHRCDAVLAAMEQVDLPLLLHGEVTDSNIDIFDREKVFIEKYLIPLREKFPRLRVVLEHITTSDAVQFVLSANNIAATITPQHLLFSRNALFKGGICPHFYCLPILKREEHRLSLLHAATSGNPKFFLGTDSAPHARNSKESLCGCAGCYSALHAMELYAEAFESVNSLDKLEAFASFYGPDFYQLPRNTAQITLMKNPWRIPAELPFPESGLVPLRAGEEITWQMV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.081 kDa
Sequence
MTHLTLTRPDDWHIHLRDGDSLADTVRDAGRYMGRAIVMPNLVPPVTTTEAAIAYYERIKAHSSTAFEPLMVLYLTDKTSPDEIRAAKASGKVVAAKLYPAGATTNSDSGVTDVNNIYGVLKAMEEEGLLLLVHGEVTDSAIDIFDRERIFIENILSKVVADFPGLKIVLEHITTKDAVDFVMSAGDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLAAATSGSKKFFLGTDSAPHAKDKKEAACGCAGSYTAHAALELYAEAFEAEGALDKLEAFASFNGPDFYGLPRNADTVALVKSPWQVPESYPLGSTTVVPIRAGEIIGWKVED
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Aliivibrio fischeri (strain ATCC 700601 / ES114)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.794 kDa
Sequence
MTTLTITRPDDWHLHLRDGDVLTDTVRDSGRYNGRALIMPNLVPPVTTTEQALSYRERIQAENKSDSFAPLMSLYLTEKTTSEEIRKAKATGHIVAAKLYPAGATTNSDSGVSDVKNVYPILKTMQEEGMLLLIHGEVTTHDIDIFDREKTFLDTVLAPIVNDFPELKIVLEHITTKDAADFVKNAGPNVAATITAHHLLFNRNHMLVGGIKPHFYCLPILKRNTHQQALVEAATSGNPKFFLGTDSAPHAKDKKEAACGCAGSYTAHASIELYAEVFENEGKLENLEAFASFNGPDFYNLPRNTDTITLVKEAWIAPETMAFGNDFVVPIRAGEAVEWLVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Aliivibrio fischeri (strain MJ11)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.808 kDa
Sequence
MTTLTITRPDDWHLHLRDGDVLTDTVRDSGRYNGRALIMPNLVPPVTTTEQALSYRERIQAENKSDSFAPLMSLYLTEKTTSEEIRKAKATGHIVAAKLYPAGATTNSDSGVSDIKKVYPILKTMQEEGMLLLIHGEVTTHDVDIFDREKTFLDTVLAPIVNDFPELKIVLEHITTKDAADFVKNAGPNVAATITAHHLLFNRNHMLVGGIKPHFYCLPILKRNTHQQALVEAATSGNPKFFLGTDSAPHAKDKKEAACGCAGSYTAHASIELYAEVFENEGKLENLEAFASFNGPDFYNLPRNTDTITLVKEAWIAPETMAFGNDFVVPIRAGEAVEWLVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Aliivibrio salmonicida (strain LFI1238)
Length
342 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.79 kDa
Sequence
MTTLTITRPDDWHLHLRDGDVLTDTVRDSGRYNGRALIMPNLVPPVITTEQALSYRERIQAVNSSNTFAPIMSLYLTEKTTSDEIRKAKATGYIVAAKLYPAGATTNSDSGVSDVQKVYPILKTMQEEGMLLLIHGEVTTHDIDIFDREKTFLDTVLAPIVNDFPELKIVLEHITTKDAADFVKNAGPNVAATITAHHLLFNRNHMLVGGIKPHFYCLPILKRNTHQLALIEAATSGSPKFFLGTDSAPHSKEKKEAACGCAGSYTAHASIELYTEVFENEGKLDNLEAFASFNGPDFYNLPRNTDTITLVKEAWITPETMSFGNDVVVPIRAGEAVEWLVK
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Sphingopyxis alaskensis (strain DSM 13593 / LMG 18877 / RB2256)
Length
340 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
36.843 kDa
Sequence
MTDRLTIRRPDDWHVHLRDGAMLAHVAPYTARQFARAIVMPNLSPPVTTAEEGRAYRDRITAAVPADLDFTPLIVAYLTDATDADEIARGHAEGVFTAAKLYPAHATTGSAHGVTDVANIMGVLERMQDIGMPLLIHGEVTDHDVDIFDREAVFIERTLEPLVRALPGLKIVFEHITTAEAAQFVADAPANVAATITPQHLHINRNAMLVGGIRPHAYCLPVAKREHHRLAVRAAATSGSPKFFLGTDSAPHAVHMKEASCGCAGIFNAPFALESYAMAFDQDGALANFEGFASEHGPRFYGLPLNEGTVTLERAEITVPDRIGDVVPFHAGETIGWRLV
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Helicobacter acinonychis (strain Sheeba)
Length
339 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.001 kDa
Sequence
MEITLFDPIDAHLHVREGVLLKAVLKYSSEPFSAAVIMPNLSKPLIDTQITLEYEGEILKNSSNFKPLMSLYFNDGLTLEELQHAKHQGIKFLKLYPKGMTTNAQNGTSDLLGEKTLEILEDAQKLGFILCIHAEQAGFCLDKEFLCHSVLETFAHSFPKLKIIIEHLSDWRSIALIEKHDNLYATLTLHHISMTLDDLLGGSLNPHCFCKPLIKTQKDQERLLSLALKAHPKISFGSDSAPHVISKKHSANIPAGIFSAPILLPALCELFEKHNALENLQAFISDNAKKIYTLDNLPSKKVRLSKKPFIVPTHTLCLNEKIAILREGETLSWNIQEIA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Helicobacter pylori (strain P12)
Length
339 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.996 kDa
Sequence
MEITLFDPIDAHLHVRENALLKAVLRYSSEPFSAAVIMPNLSKPLTDTPTTLEYEEEILNHSSNFKPLMSLYFNDDLTLEELQRAHEKGIRFLKLYPKGMTTNAQNGTSDLLGEKTLEILENAQKLGFILCIHAEQAGFCLDKEFLCHSVLETFALSFPKLKIIIEHLSDWRSIALIEKHANLYATLTLHHISMTLDDLLGGSLNPHCFCKPLIKTKKDQERLLSLALKAHPKISFGSDSAPHFISKKHSTSIPAGIFSAPILLPALCELFEKHNALENLQAFISDNAKKIYALDNLPAKKARLSKKPFIVPTHALCLNEKIAILRGGETLSWNLQEIA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Helicobacter pylori (strain G27)
Length
339 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.022 kDa
Sequence
MEITLFDPIDAHLHVREDALLKAVLRYSSEPFSAAVIMPNLSKPLIDTPTTLEYEEEILKNSSNFKPLMSLYFNDGLTLEELQRAQEKGIRFLKLYPKGMTTNAQNGTSDLLGEKTLEILENAQKLGFILCIHAEQAGFCLDKEFLCHSVLETFALSFPKLKIIIEHLSDWRSIALIEKHTNLYATLTLHHISMTLDDLLGGSLNPHCFCKPLIKTKKDQERLLSLALKAHPKISFGSDSAPHFVSKKHSASIPAGIFSAPILLPALCELFEKHNALENLQAFISDNAKKIYTLDNLPNKKARLSKKPFIVPTHTICLNEKIAILRGGETLSWNLQEIA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Helicobacter pylori (strain HPAG1)
Length
339 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
38.044 kDa
Sequence
MEITLFDPIDAHLHVRENALLKAVLRYSSEPFSAAVIMPNLSKPLIDTPTTLEYEEEILKNSSNFKPLMSLYFNDDLTLEELQRAHEKGVRFLKLYPKGMTTNAQNGTSDLLDEKTLEILENAQKLGFILCIHAEQAGFCLDKEFLCHSVLETFALSFPKLKIIIEHLSDWRSIALIEKHDNLYATLTLHHISMTLDDLLGGSLNPHCFCKPLIKTKKDQERLLSLALKAHPKISFGSDSAPHFVSKKHSANIPAGIFSAPILLPALCELFEKHNALENLQAFISNNAKTIYGLDNLPSKKARLSKKPFIVPTHALCLNEKIAILRGGETLSWNLQEIA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Helicobacter pylori (strain J99 / ATCC 700824)
Length
339 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.915 kDa
Sequence
MEITLFDPIDAHLHVRENALLKAVLEYSSEPFSAAVIMPNLSKPLIDTPITLEYEEEILKNSSNFKPLMSLYFNDGLTLEELQRAKNKGIKFLKLYPKGMTTNAQNGTSDLLGEKTLEVLENAQKLGFILCVHAEQAGFCLDKEFLCHSVLETFALSFPKLKIIIEHLSDWRSIALIEKHDNLYATLTLHHISMTLDDLLGGSLDPHCFCKPLIKTKKDQERLLSLALKAHPKISFGSDSAPHFISKKHSANIPAGIFSAPILLPALCELFEKHNALENLQAFISDNAKKIYALDNLPSKKAHLSKKPFIVPTHTLCLNEKIAILRGGETLSWNLQEIA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Helicobacter pylori (strain Shi470)
Length
339 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.998 kDa
Sequence
MEITLFDPIDAHLHVRENALLKAVLRYSSEPFSAAVIMPNLSKPLINTPTTLEYEEEILNHSSNFKPLMSLYFNDGLTLEELQRAQEKGVRFLKLYPKGMTTNAQNGTSDLLGEKTLEILENAQKLGFILCIHAEQAGFCLDKEFLCHSVLETFALSFPKLKIIIEHLSDWRSIALIEKHDNLYATLTLHHISMTLDDLLGGSLNPHCFCKPLIKTKKDQERLLSLALKAHPKISFGSDSAPHFISKKHSANIPAGIFSAPILLPALCELFEKHNALENLQAFISDNAKKIYALDNLPAKKVRLSKTPFIVPTHTLCLNEKIAILRGGETLSWNIQEIA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Helicobacter pylori (strain ATCC 700392 / 26695)
Length
339 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
37.883 kDa
Sequence
MEITLFDPIDAHLHVRENALLKAVLGYSSEPFSAAVIMPNLSKPLIDTPTTLEYEEEILNHSSNFKPLMSLYFNDGLTLEELQCAKEKGVRFLKLYPKGMTTNAQNGTSDLLGEKTLEVLENAQKLGFILCIHAEQTGFCLDKEFLCHSVLETFALSFPKLKIIIEHLSDWRSIALIEKHDNLYATLTLHHISMTLDDLLGGSLNPHCFCKPLIKTKKDQERLLSLALKAHPKISFGSDSAPHFISKKHSANIPAGIFSAPILLPALCELFEKHNALENLQAFISDNAKTIYGLENLPSKKARLSKKPFMIPTHTLCLNEKIAILRGGETLSWNLQEIA
Protein
Dihydroorotase: pyrC

Gene
pyrC
Protein
Dihydroorotase
Organism
Serratia marcescens
Length
204 amino acids
Function
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Mass
22.899 kDa
Fragment
single
Sequence
DPAVDIFDREARFIEQVMEPIRQHFPELKIVFEHITTKEAAQYVQAGNRFLGATITPQHLMFNRNHMLVGGIRPHLFCLPILKRNVHQEALRQAVASGSDRFFLGTDSAPHLKHRKESSCGCAGCFNAPNAIPAYAAVFEQLGALEHFEAFCSLNGPRFYGLPLNEDFIELQRVPTTQPEEIALGNESVIPFLAGETLNWSLKD
Protein
Dihydroorotase: pyrC