About Products Protein Database Contact

ptn-b

Gene
ptn-b
Protein
Pleiotrophin-B
Organism
Xenopus laevis
Length
161 amino acids
Function
Secreted growth factor that mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors (By similarity). Binds cell-surface proteoglycan receptor via their chondroitin sulfate (CS) groups (By similarity). Thereby regulates many processes like cell proliferation, cell survival, cell growth, cell differentiation and cell migration (By similarity). Has antibacterial activity against both Gram-positive and Gram-negative bacteria (PubMed:20308059).
Similarity
Belongs to the pleiotrophin family.
Mass
18.173 kDa
Sequence
MHHQHGLFMLALLAFLLVMTVLGTDTGKKDKQEKKVKKSDCGDWQWSVCVPTSGDCGLGTREGTRSGKECKQTIKTQKCKIPCNWKKQFGAECKYQFQEWGDCDPETGLKTRNGNLKRALHNAECQKTVTLSKPCGKVTKPKLQESKKKKKEGKNKEKLLD