ptlI

Gene

ptlI

Protein

Pentalenene oxygenase

Organism

Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)

Length

449 amino acids

Function

Catalyzes the conversion of pentalenene to pentalen-13-al by stepwise oxidation via pentalen-13-ol, a precursor of neopentalenolactone antibiotic.

Similarity

Belongs to the cytochrome P450 family.

Mass

50.757 kDa

Sequence

MSQHTFVAGTAPGAVPVVGHAWQMMRRPLHFMSSLSAHGDLVKIRIGPTSAYVPCHPELLRQVLTNDRVFDKGGVFYDRARDIAGNGLVTCPYRDHRRQRRLMQSAFQRTQLERYSTAMRAEIDATAARWHDGTVIDAFPELYGMALRTVARTLYSTPVTEELAQRVEQAFDTVLNGLFRQMFLPHSLRRLPTPANLRYRNNLRFLHDTVQDLITEYRRDDTQRDDLLSALLASRDEDGGRLGDTEIHDQVITVMAAGTETVAGTLTWIFHLLSRHPEIEARLYEEIDTVLDGKPPHWDDLPSLSLTDRIITEALRMYPPAWIFTRLTASDVDLAGVRLPEGTTIVFSPSSVQRHSEAYDDASRFDPDRWLPDRTSAVARQAFTAFGTGARKCIGDLFARTEATLALATMLSQWRVTVEPDADVRPVALATVYHPRRLRLRLTARTPGQ

Protein

Pentalenene oxygenase: ptlI

Gene

ptlI

Protein

Type IV secretion system protein PtlI homolog

Organism

Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)

Length

61 amino acids

Mass

6.266 kDa

Sequence

MIHAHSNARLLRWAILAIAPATLGACAPNGPPGLPYPDGKPLIPINTAAPEQGSSCQTRAP

Gene

ptlI

Protein

Type IV secretion system protein PtlI homolog

Organism

Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)

Length

61 amino acids

Mass

6.294 kDa

Sequence

MIHAHSNARLLRWAILAIAPVTLGACAPNGPPGLPYPDGKPLIPINTAAPEQGSSCQTRAP

Gene

ptlI

Protein

Type IV secretion system protein PtlI

Organism

Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)

Length

61 amino acids

Function

Component of the type IV secretion system ptl required for secretion of assembled pertussis toxin (PTX) through the outer membrane.

Mass

6.294 kDa

Sequence

MIHAHSNARLLRWAILAIAPVTLGACAPNGPPGLPYPDGKPLIPINTAAPEQGSSCQTRAP