prtT

Thiol protease/hemagglutinin PrtT

868 amino acids

Appears to be specific for arginine-containing peptide bonds. Possesses hemagglutinin activity.

Belongs to the peptidase C10 family.

96.445 kDa

MKRIFYTLGLLLLCLPMLQAGPVTRSKAEQTAKNFFAKRQPTLSSSTASLRMDFVYKAAEREEALFFVFNRGEKDGFLLVAADDRFPEVIGYAFKGHFDAARMPDNLRGWLKGYEREMLAVMDGKAEPIDPIREAKPTRDLPSSIAPILETGEHASDPILWDQGYPFNTLHPLLPSGQQAYTGCVATAMGQIMRHYKWPEKASGEYDYYDDMTGTHTHYSGTFGETYNWSKMPGNISVGISPEEVKALSTFMRDVSFSVNMQFADFGSGTFSIFVERALRETFHYKKSLRYIHRSLLPGKEWKDMIRKELAENRPVYYAGADGSMGHAFVCDGYEPDGTFHFNWGWGGMSNGNFYLNLLNPGSLGTGAGDGGYSTDQEVVIGIEPASNEAPGIVPDPTITLYGLQHNMSDEALDLSVKIKNYSTYAGDVKLAYRLTLPNGTETTNPAVTVPIVWEDIIGESTGNITIPCSQFAEGKNTISILYRTDGMADWKELKHILMGLVNKIEVTMPAGDVAYSVADARIVLKDGSLSHNLKAYSDCKLSATVYNPGTEEFRSRVTFALRNTEGRLYFLGRHLVELHPGDEDGEKVSLTITGLKARAGQYMLVCTGDMELLMEDASWIELASIEVAEHTSTHSSLLVASNPQIDLLTVHRANPETLPTFSITNEGGATFSGKIEIVAIKAFSETFFQAKEEHMSLAQGETKVLSPELTANSSLYTNAELFPDGIYYIVIREQGFWDPIDLFGDYYYRIRLITDLSSSXIAGKDVSTIVLYPNPAHDYVHVAIPPTYAGSTLRLFDIQGRMQLSTKIRICRYASRRRTSSEGHLYRCGRRHGREALYSLIQSVNSKTDKGNAGWEIPSGHCPCTVC

prtT

Transcriptional activator of proteases prtT

696 amino acids

Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases including a serine alkaline protease (alk1), a metalloprotease (mep), an aspergillopepsin (pep1), a sedolisin (sed2) and two dipeptidyl-peptidases (dppIV and dppV) (By similarity).

Belongs to the prtT family.

78.917 kDa

MMHIQTLRKITILDVQDKQRCLSTNQNVPDNVFQLIACWCYFPPFLSIAKIKPLIALKAGISENPVLIGCRRIKMAHCPYSEAMTRTTSVEDVKFEIPAWDNSNVDVADGSGRPESSTSGDTIRPKGRIRRSMTACNTCRKLKTRCDLDPRGHACRRCLSLRIECKLPETAERFQDNASMWSDATAAIPSIEERLISLERSMTEMTSMMRRMMDRSPSISGSSVSMLTRSGITDETASIEGSQSSSFAPRPIRLLQDLQSDFTGEANVLPADSRSLGDLFTKGIIDPKLSQKLIQLFVDHFGIWISVDNPSDIHNELRATDPLLYSTACLLASRYVPGIPLSVIHAMYLQIRHATVNVLWNKTPLKHETLQALALLALWPTAVQKETPMDSWLLSGISINHAIISFDFLNHAPSDLIVDNDMVAKLRVWNALCLTQLQSAIGNARPFHIQQRYLEHCPRLLEHPAATFEDGKIVAEIQLYLIALKLQNFSHRMRLGDFEYEEIERWKMEWAHLLKLSLWYCQLLLYRTAMRFHWESEHLISEILRNSRLILSKFLLVRFPNALAFPDQIYYIVGYAALNLCDFSPMDPLIDQVQTFLLHLSPNEDHIAYRFSYTITELKRRCATGPNPHNVVKGAFGDTRKLSMGQQIPFMNPLMDTMMGEYGGLEHLIPEVPPNSLPDMLTSVAGELQAFRTAIL

prtT

Transcriptional activator of proteases prtT

696 amino acids

Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases including a serine alkaline protease (alk1), a metalloprotease (mep), an aspergillopepsin (pep1), a sedolisin (sed2) and two dipeptidyl-peptidases (dppIV and dppV). However, it is not a virulence determinant in leukopenic mice.

Belongs to the prtT family.

78.951 kDa

MMHIQTLRKITILDVQDKQRCLSTNQNVPDNVFQLIACWCYFPPFLSIAKIKPLIALKAGISENPVLIGCRRIKMAHCPYSEAMTRTTSVEDVKFEIPAWDNSNVDVADGSGRPESSTSGDTIRPKGRIRRSMTACNTCRKLKTRCDLDPRGHACRRCLSLRIECKLPETAERFQDNASMWSDATAAIPSIEERLISLERSMTEMTSMMRRMMDRSPSISGSSVSMLTRSGITDETASIEGSQSSSFAPRPIRLFQDLQSDFTGEANVLPADSRSLGDLFTKGIIDPKLSQKLIQLFVDHFGIWISVDNPSDIHNELRATDPLLYSTACLLASRYVPGIPLSVIHAMYLQIRHATVNVLWNKTPLKHETLQALALLALWPTAVQKETPMDSWLLSGISINHAIISFDFLNHAPSDLIVDNDMVAKLRVWNALCLTQLQSAIGNARPFHIQQRYLEHCPRLLEHPAATFEDGKIVAEIQLYLIALKLQNFSHRMRLGDFEYEEIERWKMEWAHLLKLSLWYCQLLLYRTAMRFHWESEHLISEILRNSRLILSKFLLVRFPNALAFPDQIYYIVGYAALNLCDFSPMDPLIDQVQTFLLHLSPNEDHIAYRFSYTITELKRRCATGPNPHNVVKGAFGDTRKLSMGQQIPFMNPLMDTMMGEYGGLEHLIPEVPPNSLPDMLTSVAGELQAFRTAIL

prtT

Transcriptional activator of proteases prtT

660 amino acids

Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases (By similarity).

Belongs to the prtT family.

73.604 kDa

MKRSSFDAGLDGRQQDRRHSAVPDERPTPLKISKARACAECKRHKIRCEFRPGETSCTKCLRSGIKCVVNDFSQKFVDDDGVWKARASATIQQLQAAVSHLLRQNGLPELSTYTVGDSPNGPSPAAPSYHTGNRHSMNGSPSDVKPDGPGLVVTREPSQEPDLQDRELVPAPMRSLYEVTKLRDLRHNHIEQPKSTLLEEDFLSRGLISLQEAEELFAYFSRTMNQLLWGGIILVHRDLTSVRRASSLLAAAVLTVAALHIPNRTETLNLCYSEYVSLVSSMSLTRAHTLDDVRALCVGAFWLSELSWKLSGHAVRIATELGLHQSYQKMIRGHSDQYERAQLWYLLYVCDHHFSIAYGRPPVIHEDQAIKNYETFLQAPMVVPGDIRLLAQVALFMILTEAYRTFGSDTEQALTEEDFGQLRVFNVAIDQWRLLWQPRSEYLTLAAADSPYVRTYPSKGVVLHYHFAKFQLNSLSLRALSPTNTPVFSMDRKESANIAISSAMACLNMVLEEQDIRDAIVGVPIFTHTMVTFSALFLLKVAVNWNSAYLSLDSGLVRSLVERVIELLNCVSAGERHLTRHIARGLSKMLERFDSWDMSNGVPAGTVGERAGSGVPGGANAMAQGFPPPDLIYDMVGTYGFGLDENLLDPSMANFEYLAQ

prtT

Transcriptional activator of proteases prtT

641 amino acids

Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases including a serine alkaline protease (alp1) and a metalloprotease (NpI).

Belongs to the prtT family.

72.655 kDa

MTRTTVEPIKYEAPSWEHKSVHVSDDHRRIIPNVGDDATRPKGRIRRSMTACNTCRKLKTRCDLDPRGHACRRCLSLRIDCQLPETSERFQDSTPMWSDATTAIPSIEERLTSLERSMREMTGMLRQILNQSPSVSNISVPPLARSVHTEETASIEGNSFGPFLPKPVRLIQDLQSEFFGETNRIPVESPFLGNSFEKGILDSKLSLKLVQLFVDNFGPLVSINNQSDFHNEMRNTDSLLYSTACLLASRYVPGIPPPIVHTMNLQVRHKAVNLLWEKPPLKYESLQALALLCLWPAAGQKEFPIDGWLLSGTAINHALVSFDFLNHVPSELLIDNDIAAQLRLWNAFCLTQLHFAVGNARPFHLPQRYLDYCPRLLEHPAATVEDGKVVAEIQLYLITLRLQANEQRMRFAEVEYEEIERWKVEWAHLLGKVKQRGPSRINANYSTAGDENSTFELSLWFCQILLHRTAMRFQAESERLTSEILQGSRLIISKFLQLRFVTALRVVDQAYFIVGYAALNLCDFNFLDPLIDQIQMFLLHLSPNEDHIAYRFSCMIAEFKRRCAECNDPCSAVDGSQCSFGDARKMSMEQVQFVPPLVDSMIGGYSALEQLIPEVMPHSFPESVISGMAVTEAIPVGSAPY

prtT

Transcriptional activator of proteases prtT

637 amino acids

Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases (By similarity).

Belongs to the prtT family.

70.953 kDa

MTRTGPPINPISWDTKTIVPDDGSRIDSVACQDARPKGRIRRSMTACHTCRKLKTRCDVDPRGHSCRRCLSLRLDCELPETTERFQDNASTWSDATAVPSIEERLVSLERGMGEMIHLMRQIVKSSPSMPCSPTFQTRNHSIDGTSSSDSMSSSFYPLKPAQLIRDLQAECFGERAHFSDADILGDIVTQGIVDSKLSVKLIELFVEHFGHWVSINHSSSLQRSNTLLFNTACLLASRYMPGLPQHTVRDISLYVQHAVAKVLWKPPPMTSDMLQALTLLCLYSTSIHKEGLMDDWLLSGISINHALISFNFLNTLPGDNLSPDELLAQLRLWNTLCATQLHSALANGRTVNIQQQYINQCPRILEHAGATPEDGRIVAEIQLYRIALRLQHSQSRLQFAESEYEELERWRMEWAHLLTTNGDSTLNLNLWFCQLLLHRTAARLQPDSERLLPEICGTARLIITQFLQTRFTSAPALIDHVYFIVGYAALTLCDYTLTDPLINQVRGFLLHLAPGGDNLSYRIACIVGEVQRRYSEATAVVAAGSHSSSPVAEVKGAQMFGSSHHHRTGMELSQLMSSPEGLDSLVEGYNCLEQMMPGYAASQPAFEAPDLFHHSPTTGVTGGAMPIGLVPRALHDW

prtT

Transcriptional activator of proteases prtT

623 amino acids

Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases.

Belongs to the prtT family.

70.224 kDa

MTRTVDEIKYETPSSWEHKSLDVAEDGRRLAPHSDTARPKGRIRRSMTACHTCRKLKTRCDLDPRGHACRRCLSLRIDCKLPETTDRFQDSAAMWPDATSAIPSIEERLTSLERCMREMTGMMRQMLDHSPGFANASVPHLTKSIITDENASMEGSPSSPFLPKPVRLIQDLQSDFFGEAETSPVDSPLSSDGNAKGAIDSKLSLKLLQTFVDHFGACVSIYNLSDIHNDMKAPDSLLYNTACLLASRYVPGIPTSTVHAIYLQVRHAVVNILWEKPPLKYETLQALALLCLWPATAQKEPPMDSWLLSGISINHAIIALDFLNYAPSEVMVDNETAAQLRLWNTYCLTQLHFAVGNARPFHIQQRYLDHCPRILEHPAATLEDARVVAEIQLYLMTLRLQSNSSRMRLADLDYEEIERWKREWAHLFSGESSTLELSLWFCQTLLHRTAMRLQPRSDRLASEVLQTSRLIISRFLQIRYSTALSLVDQVYFIVGYAALNLCDFNLMDPLIEQVQMFLLHLSPNEDHIAYRFSCMVAEFKRRCGSAECNDPSSTVKGSPLSSYGDSRKMSMGQAPFMPPLMDGMIEGYGFEQLMPEVMPSSFPDGILNGMPVTGLAAYRSATL

prtT

Transcriptional activator of proteases prtT

622 amino acids

Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases (By similarity).

Belongs to the prtT family.

70.51 kDa

MTRTTTLEEVKFEIPTWDNNNHIEVADGSGRSESNASGDTIRPKGRIRRSMTACNTCRKLKTRCDLDPRGHACRRCLSLRIECKLPDTAERFQDNASMWSDATAAIPSIEERLNSLERSMTEMTSMMRQMVDRSPSISGSSVSLLTRSGLTEETASVEGSQPSFIAPRPIRLIQELQSDFLGEPNVLPAESRSLSESFSNGVLDPKLSLKLIQLFVEHFGSWVSIDSPSDIHNDLRPTDPLLYRTACLLASRYVPGIPSSVIQAEYLQIRHAAVNILWNSQPMKYETLQALTLLSLWPTTIQKEAPMDSWLLSGISINHAIISFDFLNHAPAELIVDNDMVAKLRLWNALCLTQLQFAIGNARPFHIQQRYLEHCPRLLEHPAATFDDGKMVAEIQLYLVTSKLQNDPHRMRSAEIEYEEIERWKMEWAHLLTGEQHSTLELNLWYCQLLLYRTAMKCQWESEPLVSEVLRNARLIISKFLLVRFSTALGFVDQTYYIVGYAALNLCDFNPMDPLIDQVQTFLLHLSPNEDHIAYRFSYTISELKRRCTACPNPNSAVKGAFGDARKLNLGQLHFMPQVLDTMMGDYSALEQLMPEVSPHSLPDMLNNVTGELQAGYRTAIL