Protein
pH-response regulator protein palH/prr-4
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
Required for the proteolytic cleavage of the transcription factor pacc-1 in response to alkaline ambient pH.
Similarity
Belongs to the palH/RIM21 family.
Sequence
MEPRQLFSDPTADPISTAGAASNALSCASFNLPEGGILQLPNGEIITLSAPAAFKPPSCNLALRSVPNIIASGGVVGGTASGTMGLKADDDSHFSDWRDPFYASTFPQCYALAATTIIAYTLVIMLFITPRSFLDGGVVVLGRKGFTNGGGGTSIGGRPWLQKVAALSVAISLTIANAATFRAAEQQYSWGVQNAKQLQEDVLGGAELKIIRIISDTFLWLAQAQTLIRLFPRQREKVIIKWTAFALITLDVIFQSLNSFKYGGSDLTRPKFTEAVPALSYLFALALGVLYAAWVLYYSIMKKRYAFYHPLMKNMILVAVLSVVSILVPVVFFILDISKPDFAGWGDYVRWVGAAAASVIVWEWVERIEALEREEKKDGILGREVFDGDEMLEASQSEHAWPKMKRKGSGGSDSQDTESGGGGKDGGPSLSRFGAWSKISTLTSKHRTEPSSRNEPNEGSSPVAETTNDDERPRFLSPPLWPARPTPAATPVSRTDTTSAASTMYAVRYHTMTELTSYGTPPPTRNMGRLSGSESRGSSRHRDYGSASPGSAPAQDARSTQNSHVGAKASSAGSRWHALTPTVSSRDFVTRSEPRSSKMQRDENSRWDLRARVEEFAATQAENLREKFRPTLDTNNLPVTVIPAPPRRGAAIAQLCEEEELNHSSREGTVREESRNSNASGTVIAVGGAQTPIQTSFSPPPRAANSSMSTAQMPRPQLSPIVTQGSFTNNRYNHLPVTVIPAPPRQDPARAPSQPQSPSLVALGKQPARSDSSTTPSP