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prcA2

Gene
prcA2
Protein
Proteasome subunit alpha 2
Organism
Rhodococcus erythropolis
Length
255 amino acids
Function
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. The R.erythropolis proteasomes are able to cleave oligopeptides after Tyr, Phe and Leu, very poorly after Arg but not after Glu. Thus, displays chymotrypsin-like activity, low trypsin-like activity but no caspase-like activity.
Similarity
Belongs to the peptidase T1A family.
Mass
27.859 kDa
Sequence
MTMPYYASAEQIMRDRSELARKGIARGRSVVVLTYRDGVLFVAENPSRALHKVSELYDRLGFAAVGKYNEFENLRRAGIVHADMRGYSYDRRDVTGRSLANAYAQTLGTIFTEQPKPYEVEICVAEIGRFGSSTPAQLYRITYDGSIADEQEFVVMGGTTEPIVTAMRESYQRDLDLESAVRLAVGALQKGGPAPAGTTEAEPRTLDVSALEVAVLDSNRPRRAFKRIAGSSLEEMLPTPAATEDAPPANGDAPS