Protein
Pickpocket protein 28
Organism
Drosophila melanogaster
Function
Osmosensitive ion channel that mediates the cellular and behavioral response to water. Plays an essential role in gustatory water reception. Part of a complex that plays a role in tracheal liquid clearance. Probable role in sodium transport.
Similarity
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
Sequence
MRTLTESRRRQSGSSGCKKDSESDDDENTICSRAAIKRSVVYYLKNSTLHGLKYIAEESITIPERIFFGLAFVLVVILSVFFISNVYVKWSASPIIISTSAKQKLTSNMPFPAITICNLNQALLSKVDRIGRTSTNFSLLMGLCDQGGDTTISYIGTWKYFKAILVDVAQPCEKMLLYCSFGSREEDCSWLFTSILTDDGLCCNFNALHPSYLIRNYSDDVRLETAHPNTRYELIDWTPEKGYARNLPEFYFPRTSGGTGIRMGLTVVLNASIAEYYCTKSMSVGFKVLVHNPAELPKVSNYGFVVTAGREARIPIEPVYEDALPTIRSIKKSVRRCLFSDENDLAYYRTYSRKNCELECEAKLLLRECSCVLYYLPRIDPLARVCGPNDNQCTDRVQTEIESSLTNLSCENCWPGCFELTYRATLSTASIVSDPRFQAGENLPEYIFHGPYSNASEISILHFYYMTNIFRSTTKSEMFGFTEFLSNTGGLLGLFMGFSIFSVIEIFFYITVRPYCASRTLRQRHKRRLEQLSWLTPIRMPVRRALRRNRGGLLRNPPPPAYSDLQKFRGKLDKPETCKRKLWRTLQVRPVVDRADEELPTYPYLD