pph-5

Gene

pph-5

Protein

Serine/threonine-protein phosphatase 5

Organism

Caenorhabditis elegans

Length

496 amino acids

Function

Serine/threonine-protein phosphatase (PubMed:23569206, PubMed:26593036). Dephosphorylates cdc-37 (PubMed:23569206). Probably by dephosphorylating separase sep-1, may be involved in sep-1-mediated exocytosis of cortical granules during meiotic anaphase and mitotic cytokinesis (PubMed:21878498).

Similarity

Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

Mass

56.462 kDa

Sequence

MAATITDDIVATVLESIEEKSYEDEKEKAGMIKDEANQFFKDQVYDVAADLYSVAIEIHPTAVLYGNRAQAYLKKELYGSALEDADNAIAIDPSYVKGFYRRATANMALGRFKKALTDYQAVVKVCPNDKDARAKFDECSKIVRRQKFEAAISTDHDKKTVAETLDINAMAIEDSYDGPRLEDKITKEFVLQLIKTFKNQQKLHKKYAFKMLLEFYNYVKSLPTMVEITVPTGKKFTICGDVHGQFYDLCNIFEINGYPSETNPYLFNGDFVDRGSFSVETIFTMIGFKLLYPNHFFMSRGNHESDVMNKMYGFEGEVKAKYTQQMCDMFTETFCWLPLCHLINEKIFVCHGGLFKEDGVTLEDIRKTDRNRQPPDEGIMCDLLWSDPQPINGRSPSKRGVGCQFGPDVTSKWCETNGIEYVVRSHEVKPEGYEMHHNGQCFTVFSAPNYCDQMNNKGAFITITGDNLTPRFTPFDAVPHPKLPPMAYANSLFGFN

Protein

Serine/threonine-protein phosphatase 5: pph-5