Protein
1-deoxy-11-beta-hydroxypentalenate dehydrogenase
Organism
Streptomyces arenae
Function
Catalyzes the oxidation of 1-deoxy-11-beta-hydroxypentalenic acid to 1-deoxy-11-oxopentalenic acid in the biosynthesis of pentalenolactone antibiotic.
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Sequence
MHSQTRAAVVTGAASGIGLALSARFARAGAGVVMADVEGGALHRRAAELIAEGARVTAVTADLTDPDAVERLAETAFDRLGDIDVVCNNAGVLGPVGQPLWEVPLERMRQVFEVNHWAHVLVARAFVPRLLERGRPAHLIHTASMSAFVVGAGSAAYAASKHADLAVARSLRADPPGDLRGTAVRVSVLCPGRVDTPMVEGLTAPRGAGGDTSVSAEDVAGVVWEALGSDRFYLFSNSDAPLRLRDQFDDVWRHVPLPPPSPEEELWPVPKTTTATTATTKH