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pnoA

Gene
pnoA
Protein
Nitronate monooxygenase
Organism
Pseudomonas sp
Length
349 amino acids
Function
Nitronate monooxygenase that uses molecular oxygen to catalyze the oxidative denitrification of alkyl nitronates. Acts on propionate 3-nitronate (P3N), the presumed physiological substrate. Is likely involved in the degradation of P3N, that allows Pseudomonas sp. JS189 to grow on 3-nitropropionate/P3N as the sole source of nitrogen, carbon, and energy (PubMed:20382807). Also probably functions in the detoxification of P3N, a metabolic poison produced by plants and fungi as a defense mechanism (By similarity). Is not active against 3-nitropropionate, nor with neutral or nitronate forms of 1-nitropropane, 2-nitropropane, nitroethane, nitromethane, 1-nitropentane, and 2-nitroethanol (PubMed:20382807).
Similarity
Belongs to the nitronate monooxygenase family. NMO class I subfamily.
Mass
36.457 kDa
Sequence
MSNSLLSLLNIELPIIQSPMVGVSTPRLAAAVSNAGGLGSIGIGASNVEQARAMLRETAALTDRPFNVNLFCHVPARADAAREAQWLAFLAPLFAEFESPAPAALREIYTSFVEDFAMLEMLLEEKPAVVSFHFGLPPQSSIDALKDAGIVLLACVTNLAEAQQAEHAGVHALVAQGYEAGGHRGVFDPQQDSEMGTFALVRVLTDACQLPVIAAGGIMDGAGIKAVMQLGASAAQLGTAFILCPESSANPAYRDALQGPRAHQTRVTSAISGRPARGMVNRNYIDLETNAPALPDYPIAYDANKALNAAAANKANTDFAVQWAGQGAPLARSMPAAALVNLLAAEMKA