plx-2

Plexin-2

1773 amino acids

Involved as a receptor for mab-20/sema-2a in the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, involved in precursor cell sorting and in the formation of distinct sensory rays. Involved in axon guidance of SDQL neurons during neurogenesis.

Belongs to the plexin family.

194.786 kDa

MLFIESAFLVLTSLSAAEAATPFEGGVKQKVFHSAGHIDDFIVSRDQQTIYIASINRITSLHSSNLSIQNEVSIGPVQDSPWCSADGKSCLKDNRPFSTDVHTKILQILPSGQLLQCGSVKLGSCSTFNSKLSLITEASTPVAANSPDASTVSQIIDNRLVVAASPTKESPGCNPNLPGLNVENAGDLEGEAAVYLRAAYRSSFRFVTTFSHQHFIFVVATVTPRETRLPVTTRLIRFCKNDTKFVSYSEIELQCRGEDNTNYPFLTAVVQTGDKLIASFSASPTSSKNSICVFSMQKVKLTFWYNVDRCRSGTDSIKLSHIGRDTKCVNKAHIPLDEDSCELGVGGSIELVEMSTIDVLAKVTSLMAVDQKALFAGTSSSQIVMLKWDEQNSNKLEEYGRKEIGDGRTGSEVVKMTRFGDFILVQMPYGIVMEELSTCAHHESCTDCQVSVDPLCQWCHPTQSCTTSSRCSGPLTTQCPIVDGDPIPSMVSVNSSTSISFNIHHLPPPVGFVYKCYFGSKSHSKSTKATWTASGISCPSEMFGSPKTFEISLMTSISKNPISRHNFTVFDCAGYSTCSTCMSSEFGCQWCSHKCSSSCGSASAKACVKIQPMKVPIAIGSQQEIVLEALNLDTLDRKTEHFCKVNGQVAPAKIASDSIRCGKIQLAGSNETNANMVVPLSLMANDVVVDIANVSLYSCSNLAADCSSCLALSPSLSCGWCNRKCSHECHESKATAVCDPPKIDRFEPSSGPVEGGTVIKVYGNDLGMSVEDVRGKIYVAGSRCNIVEYQVSNMIACQVDKGVSSGPIKISVGRATMAVAESSDLFSFVRVSIFSAYPLYGPISGGTRITLYGQNLSSGSRISVTVGGLPCPIERINSSTVLTCLTPSGSSIGKSAKVVVHVDHSQIQLDQPFEYRSDPSVNSIFPLSSFKAGGRIVSVQGSSFNTVQSARMFLISSPTPPFEIISDLAPCHIINSTLMTCMTPKILETITRRVEYTRQPVGFLMDNVTAVANLGRRIQMSVYPNPSLSPFKGIRYHQGEQSLILEGHNLNLAAEPNDFKIFVGSERCYVTLVDVRQLVCSGPLKQPKPTDERGVPINGDNPLVTVIVGSLRMELGLIEYSDHALPSRLSFLILGLLLFTVITLIVMCLIFKRRRQEREKEYRKIQLQMENLENNVRKECKQAFAELQTNLVLSPKSTGTITSPELIHFPHFVENLLWADQNLTSAPSLARTLPVTLAQFHALLSFKGFIFTIVEAAESDVSISTSEKSTLASLLISVLLRNFSYCTEIVVDLLKAHIARSVQAKRAELLFRNSDSVVEKMFSKWMSICLYSHLTPQMNSYFYLYKALQYQTDKGPVDAVTGDARYTINEAKLLRESVETKTLKIHIVPFEKCDETTHLEVHACDAICQLKQKVASAVYKETPYSQRPRITQFELKLKCAKRGDIKLTDVSAVETLSQKKLPVKLLTLADYGIQDGATLEMTSAVYTAESYRNSLADSGQSSWSSLDRCSPIYSSSKYYHLTNPSSGTMTFKKRTSPSEIPKSIPEVYLTRLLTSKGTVETYVEDFLESVLYMHDSSYPPILKFFFDILDREASINGVSENICQQWKANGYVLRMWTNFVKNPQLVFDVPHSVSMDANLSTVAQTMMDCFSFSEPVLGAHSPSSRLLFAKDVARLRPLSVDLFKRVKNSPPLGMEELRTELVNMANDVSTCKGSSLALSELLSWVRGNGIRISQLLSSNQETSQQRLPQKLSQVLHVCLETDNHIYSTISDYD

plx-2

Plexin-2

1766 amino acids

Involved as a receptor for mab-20/sema-2a in the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis (PubMed:17507686). In early embryonic development, required for proper ventral closure of the epidermis (PubMed:17507686). During male tail morphogenesis, involved in precursor cell sorting and in the formation of distinct sensory rays (PubMed:15030761). Involved in axon guidance of SDQL neurons during neurogenesis (PubMed:26903502).

Belongs to the plexin family.

195.78 kDa

MLPESVFLLLISHFLRAVTQPPFETEGVKQKLFHFSGHIDDFIVSRDQQTIYVASLNRLTSLSISNFSIQHEVSLGPVQDSPWCSADGKSCLKDNRPFPTDVRTKILQILPTNQILQCGSVKLGSCSTFNSKLSLITESTIAVAANSPDASTVSKIIDNRLIVAASATKESPYRDPFPAVAIRNLPGLNVENAGDLEGEAAVFLRAAYKNAFKFLYTFTHQHFVFVVAMVTPRESRLPMTTRLIRFCRNDTKFESYSEIELQCRGEDNTNYPFLNAIIQSYDKLIASFSTSSTSPKSSICVFSMQKVKLTFWYNVDRCRSGTDSIRLPHIGRDTKCVNKAHIPLDEDSCELGVGGSIELVEMSTKDIMGKVTSLMAVDQKAIFAGTTTSQIVMFKWDEHHSNQLEEYGRKEVGDGRTGSEVSKMVKFGDFVIVQMPYGIILEELSTCSHHSSCTECLVSVDPLCQWCHPTQSCTTSARCTSPVTSQCPIVDGDPIPSIVSVNSSTPISFNIHHLPPPVGFTYRCQFGTSTSSIKANWTTTGVSCPSEIFTSPNTFEILLLTSISNNPISRHNFTVYDCSGYGTCSSCMSSEYNCAWCSGLHKCSNSCGALEKSKACVKIQPMRLPIAIGSQQEIVLEASNLDTLDRRHEHFCKVNEQVSLAKIASDSIRCGKIQLTLSNTTSANMVVPLSLITRDSVIDIANVSLYSCTNLASDCSSCLALSPSLSCGWCNRQCSHECHESKATAVCDPPRIDKFEPTSGPIEGGTIIKIYGNDLGMSVEDVRGKIYVAGSRCNIVEYHVSNMIACQVDKGVSSGPIRISVGRATVAVAESSELYSFVRTSIFSAYPLYGPISGGTRITLYGQNLSSGSQTSVTVGGMPCPIERVNSSTVLTCLTPSGTRIGKSARVVVHVDHSQTQLDQPFEYRSDPSISSIFPMTSFKAGGRIVYVQGNSLNTVQTAKLFLISSPTPPFYIISDLAPCHIINSTLMTCMTPKILETITRRVEYTRQPMGIYPNPTLSPFKGVRYHQGEQSLILEGHNLNLAAEPNDFKIFIGNERCYVTLVDVRQLVCSGPVRQPKATDERGIPINGDNPLVTVIVGSLRMELGLIEYSDHALPSRLSLLILGLLLFIVVTLTVMCLVFKRRRQEREKEYRKIQLQMENLENNVRKECKQAFAELQTNLVLSPKSANSVNLGPELINFPHFVENLLWSDNNLTSAPSLARTLPVTLAQFHALLSFKGFIFTIVEAAESDVSISTSEKSMLASLLISVLLRNFSYCTEVVVDLLRAHIARSVQNKRAELLFRNSDSVVEKMFSKWMSICLYSHLTPQMNSYFYLYKALQYQTDKGPVDAVTGDARYTINEAKLLRESVDTKTLKIRVIPFEKCDESIDLEVHACDAICQVKQKVASAVYRETPYSQRPRITQFELKYKCPKRGDVKLTDVLPIETLSQKKLPVKLFTLADYGISDGCTLEMSPAVYTAESYRNSLADSGQSSWSSLDRCSPIYSSSKYYHLTNPSSGTMTFKKKSSNDSNLLPKSIPEVYLTRLLTSKGTVETYVEDFLESVLYMHDSSYPPILKFFFDILDREASVNGVSENICQQWKANGYVLRVWANFVRNPQLVFDVPHSISMDANLSTVAQTMMDCFSFSEPVLGAHSPSSRLLFAKDVARLRPLSVDLFKRVKNSPPLGMDELRTELVNMANDVSTCKGSSLALSELLSWVRGNGIRISQLLSSNEQFSQQRLPQKLSQVLHVCLETDNHIYSTISDYE