Organism
Dictyostelium discoideum
Function
Hydrolyzes membrane phospholipids, such as PtdCho (phosphatidylcholine), producing the free headgroup and PtdOH (phosphatidic acid; signaling molecule on its own).
Similarity
Belongs to the phospholipase D family.
Sequence
MMMKLLFLIALFGCVVNSIRINNDNGLSFQSNCLGGSIQIAESIPLALNLQSNLSTHDAWMELITNAKKSIDMGIFYMTLTDGGQLDPVYGGQLGLDIYKALVDANSRGVSIRIVQNQPSSSMPDTDTQNLAKLGVQVRSINWPSLVGAGILHTKVIVVDQVSAYLGSANLDWRSLAQVKELGVLFQNCPSMVSDTEIAFQQYWDAAVVTELPSDWGVQYQAAYNQTNMASLLLNGNEKFEMFLAVSPPQFVSTDRTGDIDALVSAMNGATKTICISVMDYIPASLYNSPNTFWPVMDNALRAAAYNRGVQVRMLISHWNHTNYAIPQWLHSLDQVNNIDVRWFVVPDFPNEPQVPFTRVNHAKYMVTDEQSYVGTSNWSEDYYTNTGGLSYNIYNDEFTSQLQSIFDRDWNSPYSFPVTTY