Protein
Secreted effector protein PipB
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Function
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Does not appear to be required for the formation or the maintenance of either Salmonella-containing vacuole (SCV) or the Salmonella-induced filaments (Sifs). Not required for intracellular replication in phagocytic cells.
Sequence
MPITNASPENILRYLHAAGTGTKEAMKSATSPRGILEWFVNFFTCGGVRRSNERWFREVIGKLTTSLLYVNKNAFFDGNKIFLEDVNGCTICLSCGAASENTDPMVIIEVNKNGKTVTDKVDSERFWNVCRMLKLMSKHNIQQPDSLITEDGFLNLRGVNLAHKDFQGEDLSKIDASNADFRETTLSNVNLVGANLCCANLHAVNLMGSNMTKANLTHADLTCANMSGVNLTAAILFGSDLTDTKLNGAKLDKIALTLAKALTGADLTGSQHTPTPLPDYNDRTLFPHPIF