pikD

Gene

pikD

Protein

Phosphatidylinositol 4-kinase

Organism

Dictyostelium discoideum

Length

1180 amino acids

Function

Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate.

Similarity

Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

Mass

132.681 kDa

Sequence

MNKISDTIIITSTSNEDEVDNNNNNNNLKEIDRSPRVNNNNNNILTNVNNNKNNTITSSGGSDSSSSSSNNNNNKIKKSKKHKEKEHMDSIVKLYSGKFDSWMVICHLFKYRDNPGIVDFLCNKMYNLEDKDIDFYITQLCILLINQPHDQKASFSSLARFILDRCASSFRFAIKAYWIFQAFEEDGEKNLFSIEGSVYLHSPSTSPKDVPMYSNDQIVPIDLDKIYNQSQYDDDDFDLSDDDGGFEIIKKNDHHYENDHHIENDPKKDINSNNNNNNNINNNNSNNDDNNNNEILPNENSDNSINDENNQYGNSNNNNNISGENDNIKIDINSQNKSDSNIETLNSTLCEETKTSPIKDDMENNNNNNNNNNNNNNNNNNNNNINNNNINNNNINNNNNINYGHINGSLSTLDGIGQPYISQPNDPIENITQILKRNRIIYKKVEEKKELATRLREFCEMSVITCSRPLITRPRTSSLPSPLISYNSGKIGGNYHKILSPSSVDSTSLISEDDKIIEKEEEDNVVEDDDDDEVNSEDFIPTATTTATTTTTTIPNHLSKTTSGVGINSNSSTPININSAGAGAGGGGEINHIGYDDISYLDKCKTPPAESKLSDHDFEFELSKSHRCDYLNDILSFIQKLAHISKILLPIPIDLRQAKLKHEISLLNINLPLGLYVPLWQSSNHHCVVRIPPEEVKILNSRERVPFLLVLEVIESEHEALSSNIFEVVSSYLQYTTGNSALKKDDIKRKYYSEKFKKSFLNSSINSTISNSSDSCTTETTTTSPVATSPTLPINIPHSKLINDGSNSISKSLPVTPTQSTVLNNLISTSTAISPPSQQQQLPSPSNTTTTTTTTTTNTNNTTTTTTTTTTTLSTSPTNEKILNENKQNSSPFGESWQEKIERYKKISPFGDYPNWRLYSVIVKTGDDCRQEQMAVQLISKFDEIWKETRLPLYLRPYSILVTSSGGGIIETIPDTMSLHNLKKSTPGFTTLLNYFKSTYGDPSGLRFRTAQSNFIESMAAYSIVTYILQIKDRHNGNILIDKEGHIVHIDFGFILSNSPGNISFESAPFKLTQELVDVMGGIQSGQFQYFKVLCVRGLIEARKQVDKIISLIEIMMSGPKMSCFVGGKEVIEQLKARFFLDVNERECSTLVENLISYSIDHFKTRYYDKYQSWLNGIYQ

Protein

Phosphatidylinositol 4-kinase: pikD