phnY

Gene

phnY

Protein

Phosphonoacetaldehyde dehydrogenase

Organism

Rhizobium meliloti (strain 1021)

Length

485 amino acids

Function

Plays an important role in phosphonate degradation by catalyzing the NAD-dependent conversion of phosphonoacetaldehyde (PnAA) to phosphonoacetate (PnA). Has low in vitro activity with the related compounds phosphonopropionaldehyde (3-oxopropyl phosphonate) and glyceraldehyde 3-phosphate.

Similarity

Belongs to the aldehyde dehydrogenase family.

Mass

52.913 kDa

Sequence

MTNAEVTIAVRHEPMRIAGRLVDTDDRVEVRYPWNDTVVGTVPAGRAEHAREAFAIAAAYQPKLTRYERQKILLATAEALAARKEEISDVITLELGISKADSLYEVGRAFDVFTLAGQMCIRDDGEIFSCDLTPHGKARKIFTMREPLTAISAITPFNHPLNMVAHKVAPAIATNNCVVVKPTELTPMTALLLADILYEAGLPPEMLSVVTGWPADIGMEMITNPHVDLVTFTGSVPVGKLIAANAHYKRQVLELGGNDPLIILNDLSDDDLARAADLAVAGATKNSGQRCTAVKRILCQESVADRFVPLVLERAKRLRFGDPMDRSTDLGTVIHEKAAALFEERVMRAAEEGADILYHPGRSGALLPPIVVDRVPHQSDLVLEETFGPIIPIVRVPDDDDATITLSNSTAFGLSSGVCTNDYRRMQKYIAGLKVGTVNIWEVPGYRIEMSPFGGIKDSGNGYKEGVIEAMKSFTNVKTFSLPWP

Protein

Phosphonoacetaldehyde dehydrogenase: phnY

Gene

phnY

Protein

2-aminoethylphosphonate dioxygenase

Organism

Uncultured bacterium HF130_AEPn_1

Length

262 amino acids

Function

Involved in the degradation of the organophosphonate 2-aminoethylphosphonic acid (2-AEP) (Probable). Catalyzes the hydroxylation of 2-aminoethylphosphonic acid to yield (2-amino-1-hydroxyethyl)phosphonic acid (PubMed:22564006).

Similarity

Belongs to the PhyH family.

Mass

30.264 kDa

Sequence

MSYFTQEQKTQWKDNGFVHLKGFLNEALAQDIKDWTQELYEWEEAPGKWMKYFETSSDTGERLLCRVENFIDYHKGIKGFLCGEMIYGMVSELMGEQAVLFKEKINFKYPGGAGFAYHQDAPAFTSFGQKYHITMMVSVDASNEENGCLRMAHGFSEEKTLEQEPDGTVCKKLAAKLDWRPLETGPGDLVLFNSYVPHYSEANTSDRSRRAMFITYNRLSEGEKRLDYFKDKREKFPPEAERIEGKDYSSAESLYNLGNPIK

Protein

2-aminoethylphosphonate dioxygenase: phnY