Function
Serine/threonine kinase regulating cell substrate adhesion, phagocytosis, motility, chemotaxis, and actin cytoskeleton organization. It is a downstream component of Rap1-regulated adhesion, and it is a regulator of myosin II phosphorylation. It is also a negative regulator of development initiation.
Sequence
MDDQQPLQTYNQPPPPLPKHIQLQIQQRQLQLQQQEEQERLQQQQQQQQQQQDQQQHKLEEGSRRRSLSDVVGGVNISNKETPKRAFRIYWANDNHMYWTLLLDSTNTVGDVSEGLKDKVPSSGTQCYLYKRTKANFGRWKDRRLSNEDSVWDIVDRRRKNHKSDPIFVLKRKKSTFSISQKKSPQNESDTSPLSSSGEFLNPYTNPTGSNNIVPSNAGHSRNTSSNSNNSANTSSNNLLAHHQFNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNSSNSNSNNSSNTTTTTTTTTTTTTTSTSTNSINTSNNNNNNNSGSNINPSSFISPMSSLVSLSLSSSPASSAPHSPTLSSQPSSPHTITPITTSPPPPQRNNSSKSLKSTMEMEPPAEYISLLSNNPPPTNGSGSRPPSGSFIPGSIVNGSRSSASDLIGFKPPVCQQQQQQQQQQQQQQQQQVQQQQQQPQQVQQLQQLQQLQQQYQQQQPQQQIQPLSPQQQSQQQQQSPVKQSESIPQSPNLQSITQSSSSNKPLSGSTGMNRSSSPSPFAKKNIGGGGGGGSLADRKNRLSVQPKDIMRLMRFYFGDSLDGTFFTIAVQNDTSAKDVCASVEQKLLLPSGSTFVSLVLPIQPNGSKIERVLGEDEIIIEVKDTWEDPSQTFFQVTHKQQAPNNKRLSRQIQAEPHVIPSEWRRSTDAISLRASSDDMWKRKSIPIFLQVTGPPNTHSHSHSPQRQLPNMSGSPHSHHHHQNNNNNNNNNNNNNNNNDLDDDDSDDESDFDVSTLRGWVHWIPSADLEYIKRIGSGTYSKVYKGKYRDKFVAIKTMRGSNMTTEQIESFKKECDILSTIQSPLLISFYGSCIEESQLSMVVEYCSKGTLHKVLNNPLLDFDWDKWFKWMTEVVEGVRYLHSMNPPMVHRDLKTLNILISSDWTAKLCDFGLTRTMTMTNVSTLGMLRGTMAYTAPEIYDGLLFNTKSDVYSLGVIMWEAIQRCISGVYLRPFHEHPISMDIQIIILTSKNKVRPKISENCPEQLKTLITRCWDENPDKRPNCDEILEILLTMKQAHDENKDEWESIRTKLPKQTIKAVSSSSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTNTNSTVNNVVVPSSSNATIVVAPSVSSNSSNINTSMDNKSMSSLSDSPVLPSVGIVSTSSLTGNSNINNNNNNIHDNNNPNNNNSNNSNNTSLDVPPVGVILTRDRRNSIIAVGEVPVIVKPPETPDGTTMVTEVFDFEVPQDSPSLEPLSSNNIISTANILNIGYVNNENNSIIIEGNKSTLNEIGNNNNNNNNNNNNNNNNNNSSNNNSINNNSSNNDENNCINNCINIESNESCIKSNTPEQITLKCVDER