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phaB

Gene
phaB
Protein
Acetoacetyl-CoA reductase
Organism
Acinetobacter sp. (strain RA3849)
Length
248 amino acids
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
26.727 kDa
Sequence
MSEQKVALVTGALGGIGSEICRQLVTAGYKIIATVVPREEDREKQWLQSEGFQDSDVRFVLTDLNNHEAATAAIQEAIAAEGRVDVLVNNAGITRDATFKKMSYEQWSQVIDTNLKTLFTVTQPVFNKMLEQKSGRIVNISSVNGLKGQFGQANYSASKAGIIGFTKALAQEGARSNICVNVVAPGYTATPMVTAMREDVIKSIEAQIPLQRLAAPAEIAAAVMYLVSEHGAYVTGETLSINGGLYMH
Protein
Acetoacetyl-CoA reductase: phaB

Gene
phaB
Protein
Acetoacetyl-CoA reductase
Organism
Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D)
Length
246 amino acids
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
26.124 kDa
Sequence
MARIALVTGGIGGIGTSICTRLAKDGCTVVANCHPSEAAAAEEWKQARAAEGFDIAVFTADVSSFDDSARMVREITEQVGPIDILVNCAGITRDKTFKKMEQAHWEAVINVNLNSVFNVTRQVWDGMLERGFGRIINISSVNGQRGQFGQANYSAAKAGMHGFTMALAQEGASKGVTVNTISPGYVETAMTLAMNDDVRNSIISGIPMRRMAQPDEIAAAIAFLAGDESGYMTGANLPVNGGLFMH
Protein
Acetoacetyl-CoA reductase: phaB

Gene
phaB
Protein
Acetoacetyl-CoA reductase
Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Length
246 amino acids
Function
Catalyzes the chiral reduction of acetoacetyl-CoA to (R)-3-hydroxybutyryl-CoA. Is involved in the biosynthesis of polyhydroxybutyrate (PHB), which is accumulated as an intracellular energy reserve material when cells grow under conditions of nutrient limitation.
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
26.37 kDa
Sequence
MTQRIAYVTGGMGGIGTAICQRLAKDGFRVVAGCGPNSPRREKWLEQQKALGFDFIASEGNVADWDSTKTAFDKVKSEVGEVDVLINNAGITRDVVFRKMTRADWDAVIDTNLTSLFNVTKQVIDGMADRGWGRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVSPGYIATDMVKAIRQDVLDKIVATIPVKRLGLPEEIASICAWLSSEESGFSTGADFSLNGGLHMG
Protein
Acetoacetyl-CoA reductase: phaB

Gene
phaB
Protein
Acetoacetyl-CoA reductase
Organism
Paracoccus denitrificans
Length
242 amino acids
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
25.615 kDa
Sequence
MAKVALVTGGSRGIGAAISKALKEAGYTVAANYAGNDDAARAFTEETGIKTYKWSVADYDACAAGIKQVEEELGPIAVLVNNAGITRDAMFHKMTPQQWKEVIDTNLTGLFNMTHPVWSGMRDRKYGRIVNISSINGQKGQAGQANYSAAKAGDLGFTKALAQEGARAGITVNAICPGYIGTEMVRAIDEKVLNEGIIPQIPVAAWAEPEEIARCVVFLASEDAGFITGSTHQAPNGGQFFV
Protein
Acetoacetyl-CoA reductase: phaB

Gene
phaB
Protein
Acetoacetyl-CoA reductase
Organism
Rhizobium meliloti (strain 1021)
Length
241 amino acids
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
25.37 kDa
Sequence
MSRVALVTGGSRGIGAAICVALKAAGYKVAANYAGNDERAKAFEQESGIPVYKWDVSSYQACVDGIARVEADLGPVDILVNNAGITRDAMFHKMTPEQWGEVIGTNLTGVFNMTHPLWSGMRDRGFGRIVNISSINGQKGQMGQVNYSAAKAGDLGLTKALAQEGAAKGITVNAICPGYIGTEMVRAVPEKVLNERIIPQIPVGRLGEPEEVARCVVFLASDDAGFITGSTISANGGQYFA
Protein
Acetoacetyl-CoA reductase: phaB

Gene
phaB
Protein
Acetoacetyl-CoA reductase
Organism
Zoogloea ramigera
Length
241 amino acids
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
25.285 kDa
Sequence
MSRVALVTGGSRGIGAAISIALKAAGYKVAASYAGNDDAAKPFKAETGIAVYKWDVSSYEACVEGIAKVEADLGPIDVLVNNAGITKDAMFHKMTPDQWNAVINTNLTGLFNMTHPVWSGMRDRSFGRIVNISSINGQKGQMGQANYSAAKAGDLGFTKALAQEGAAKGITVNAICPGYIGTEMVRAIPEKVLNERIIPQIPVGRLGEPDEIARIVVFLASDEAGFITGSTISANGGQFFV
Protein
Acetoacetyl-CoA reductase: phaB

Gene
phaB
Protein
Acetoacetyl-CoA reductase
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
240 amino acids
Function
Catalyzes the reduction of acetoacetyl-CoA to (R)-3-hydroxybutyryl-CoA (PubMed:26358291). When expressed in E.coli with Synechocystis PhaA, PhaC and PhaE confers the ability to synthesize up to 12% (w/w) poly(3-hydroxybutyrate) (PHB) depending on the carbon source (PubMed:11010896).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
25.333 kDa
Sequence
MLSLGLEDKVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNTEALGVVANVTDLESMTAAAAEITDKLGPVYGVVANAGITKDNFFPKLTPADWDAVLNVNLKGVAYSIKPFIEGMYERKAGSIVAISSISGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANAVAPGFIDTEMTLAIREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVASSYVTGEVLRVNGAHHT
Protein
Acetoacetyl-CoA reductase: phaB